Research Surgery and Care of the Research Animal

Research Surgery and Care of the Research Animal

Patient Care, Vascular Access, and Telemetry

1st Edition - August 12, 1986

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  • Editors: William I. Gay, James E. Heavner
  • eBook ISBN: 9781483259536

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Methods of Animal Experimentation, Volume VII: Research Surgery and Care of the Research Animal, Part A is a collection of papers that deals with methods used in animal experiments involving patient care, vascular access, and telemetry. This book concerns technologies in experimental surgery — complicated procedures requiring longer observation time of the test animal, and an increase in the spectrum of animals that can be used. One paper describes the anesthesia, analgesia, and kinds of restraints that are suited for the test animal. A wide array of choices of inhalational agents, injectable, local anesthesia (lidocaine), analgesics (opioids and aspirin), and restraint (nonanesthesia and neuromuscular-blocking agents) is available for the researcher to choose from. Several authors also describe the use of telemetry devices that are implantable in test animals to achieve minimal interference from the investigator. These devices include sensors such as flow transducers and probes to use in pulse or continuous wave-applications; electromagnetic flowmeters for blood monitoring; and integrated circuits for various applications. One paper discusses postoperative care including a patient care checklist, treatment of common postoperative complications, as well as venous catheters for fluid administration. This text will be appreciated by veterinarians, technicians dealing with laboratory animals, and researchers designing animal and medical experiments.

Table of Contents

  • Foreword


    Chapter 1 Anesthesia, Analgesia, and Restraint

    I. Introduction

    II. General Anesthesia: Inhalation Agents

    III. General Anesthesia: Agents Given by Other Than the Inhalational Route

    IV. Local Anesthesia

    V. Analgesia

    VI. Restraint

    VII. Application Notes

    VIII. Concluding Comments

    Appendix I: Sources of Equipment, Supplies, and Drugs

    Appendix II: Drug Schedules per Controlled Substance Act of 1970 (U.S.A.)


    Chapter 2 Implantable Telemetry

    I. Introduction

    II. Applications

    III. Sensors

    IV. Systems

    V. Integrated Circuits

    VI. Implant Technology

    VII. External Electronics Used with Implantable Telemetry


    Chapter 3 Postoperative Care

    I. Introduction

    II. Postoperative Patient Care Checklist

    III. Causes and Treatments of Common Postoperative Complications

    IV. Introduction and Maintenance of Indwelling Venous Catheters for Fluid Administration


    Chapter 4 Indwelling Vascular Cannulas for Remote Blood Sampling, Infusion, and Long-Term Instrumentation of Small Laboratory Animals

    I. Introduction

    II. Selection of Materials for Intravascular Catheters

    III. Design of Experiments Requiring Blood Sampling and Intravascular Access

    IV. Physiological Constraints Imposed by Small Body Mass

    V. Blood Sampling and Injection of Animals without Cannulas

    VI. Surgical Techniques for Intravascular Cannulation

    VII. Blood Sampling and Infusion from Intravascular Cannulas

    VIII. Remote Access Intravascular Cannulas

    IX. Implantable Infusion Pumps

    X. Overview and Conclusions


    Chapter 5 Vascular Access in Large Laboratory Animals

    I. Introduction

    II. General Considerations

    III. Methods of Blood Access

    IV. Factors Influencing Animal Selection

    V. Conclusion



Product details

  • No. of pages: 266
  • Language: English
  • Copyright: © Academic Press 1986
  • Published: August 12, 1986
  • Imprint: Academic Press
  • eBook ISBN: 9781483259536

About the Editors

William I. Gay

James E. Heavner

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