Recent Progress in Hormone Research - 1st Edition - ISBN: 9781483198262, 9781483223292

Recent Progress in Hormone Research

1st Edition

Proceedings of the 1966 Laurentian Hormone Conference

Editors: Gregory Pincus
eBook ISBN: 9781483223292
Imprint: Academic Press
Published Date: 1st January 1967
Page Count: 702
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Recent Progress in Hormone Research, Volume 23 is a collection of papers presented at the 1966 Laurentian Hormone Conference, held at Mont Tremblant, Quebec, Canada. This conference explores four major areas of research, including thyroid physiology, thyroid hormones, contemporary developments in peptide hormone chemistry and biochemistry, and special studies of insulin, particularly in man. This book is organized into four parts encompassing 14 chapters. Part I deal with the factors controlling thyroid stimulation and special studies of the mode of action of thyroid hormones, including antithyroid drugs. Part II describes the mode of action of steroid hormones and hormonal steroids based on the effects on normal and neoplastic tissues. This part also looks into a definitive segment of research in endocrinology with the metabolism of the steroid hormones in vivo and in vitro. The discussion of an important clinical condition involving adrenocortical steroid production is given in the chapter concerned with congenital adrenal hyperplasia. Parts III and IV explore the synthesis of peptide hormones and insulin. These parts also tackle the gastrointestinal hormone biochemistry, the detection of at least two insulin-like activities in human serum, and the particular control of insulin activity in man. This book is directed primarily toward endocrinologists.

Table of Contents

Preface I. Thyroid Physiology

1. The Long-Acting Thyroid Stimulator: Its Role in Graves' Disease Discussion 2. Studies of Thyrotropin Physiology by Means of Radioimmunoassay Discussion 3. Extrathyroid Effects of Some Antithyroid Drugs and Their Metabolic Consequences Discussion 4. Thyroid Hormones and the Biochemistry of Amphibian Metamorphosis Discussion

II. Steroid Hormones

5. Studies of the Mode of Action of Adrenal Steroids on Lymphocytes Discussion 6. Biochemical and Morphological Responses of Normal and Neoplastic Mammary Tissue to Hormonal Treatment Discussion 7. Formation and Metabolism of Steroids in the Fetus and Placenta Discussion 8. Studies with the 3α-Hydroxysteroid Dehydrogenase from Pseudomonas testosteroni—Enzyme-Substrate Complementarity as the Basis of Selectivity and Steric Specificity Discussion 9. Disorders of Adrenal Steroid Biogenesis Discussion

III. Peptide Hormones

10. New Approaches to the Chemical Synthesis of Peptides Discussion 11. Contemporary Developments in the Biochemistry of the Gastrointestinal Hormones Discussion

IV. Insulin and the Pancreas

12. Synthetic Insulins Discussion 13. Nonsuppressible Insulinlike Activity of Human Serum: Purification, Physicochemical and Biological Properties and Its Relation to Total Serum ILA Discussion 14. Effect of Amino Acids and Proteins on Insulin Secretion in Man Discussion

Author Index Subject Index


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© Academic Press 1967
Academic Press
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About the Editor

Gregory Pincus

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