Rare-Earth Element Biochemistry: Characterization and Applications of Lanthanide-Binding Biomolecules

Rare-Earth Element Biochemistry: Characterization and Applications of Lanthanide-Binding Biomolecules

1st Edition - April 20, 2021
This is the Latest Edition
  • Editor: Joseph Cotruvo
  • eBook ISBN: 9780323910866
  • Hardcover ISBN: 9780323910859

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Description

Rare-Earth Element Biochemistry: Characterization and Applications of Lanthanide-Binding Biomolecules, Volume 651 in the Methods in Enzymology series, continues the  legacy of this premier serial with quality chapters authored by leaders in the field. Chapters in this new release include Spectrophotometric methods to probe the solution chemistry of lanthanide complexes with macromolecules, Determination of affinities of lanthanide-binding proteins using chelator-buffered titrations, Electron Paramagnetic Resonance of Lanthanides, Characterization of lanthanoid binding proteins using NMR spectroscopy, Macromolecular crystallography for f-element complex characterization, Infrared spectroscopy probes ion binding geometries, Predicting lanthanide coordination structures in solution with molecular simulation, and much more. Additional sections cover the Characteristics of Gd(III) spin labels for the study of protein conformations, Lanthanide-based resonance energy transfer biosensors for live-cell applications, Yttrium-86 PET imaging, Aqueous Chemistry of the Smallest Rare Earth: Comprehensive Characterization of Radioactive and Non-radioactive Scandium Complexes for Biological Applications, and In vitro selection and application of lanthanide-dependent DNAzymes.

Key Features

  • Provides the authority and expertise of leading contributors from an international board of authors
  • Presents the latest release in the Methods in Enzymology series

Readership

Biochemists, biophysicists, molecular biologists, analytical chemists, and physiologists

Table of Contents

  • 1. Spectrophotometric methods to probe the solution chemistry of lanthanide complexes with macromolecules
    Gauthier Deblonde
    2. Determination of affinities of lanthanide-binding proteins using chelator-buffered titrations
    Joseph A. Cotruvo Jr.
    3. Electron Paramagnetic Resonance of Lanthanides
    Gareth R. Eaton
    4. Characterization of lanthanoid binding proteins using NMR spectroscopy
    Claudio Luchinat and Giacomo Parigi
    5. Macromolecular crystallography for f-element complex characterization
    Rebecca Abergel
    6. Infrared spectroscopy probes ion binding geometries
    Carlos R. Baiz
    7. Predicting lanthanide coordination structures in solution with molecular simulation
    David Cantu
    8. Characteristics of Gd(III) spin labels for the study of protein conformations
    Daniella Goldfarb
    9. Lanthanide-based resonance energy transfer biosensors for live-cell applications
    Lawrence W. Miller
    10. Yttrium-86 PET imaging
    Peter Caravan and Mariane Le Fur
    11. Aqueous Chemistry of the Smallest Rare Earth: Comprehensive Characterization of Radioactive and Non-radioactive Scandium Complexes for Biological Applications
    Eszter Boros
    12. In vitro selection and application of lanthanide-dependent DNAzymes
    Juewen Liu

Product details

  • No. of pages: 412
  • Language: English
  • Copyright: © Academic Press 2021
  • Published: April 20, 2021
  • Imprint: Academic Press
  • eBook ISBN: 9780323910866
  • Hardcover ISBN: 9780323910859

About the Serial Volume Editor

Joseph Cotruvo

Joseph A. Cotruvo, Jr. is Assistant Professor, Louis Martarano Career Development Professor, Department of Chemistry Pennsylvania State University, PA, USA

Affiliations and Expertise

Assistant Professor, Pennsylvania State University, PA, USA