This newly revised and updated edition of Radiation Biophysics provides an in-depth description of the physics and chemistry of radiation and its effects on biological systems. Coverage begins with fundamental concepts of the physics of radiation and radioactivity, then progresses through the chemistry and biology of the interaction of radiation with living systems. The Second Edition of this highly praised text includes major revisions which reflect the rapid advances in the field. New material covers recent developments in the fields of carcinogenesis, DNA repair, molecular genetics, and the molecular biology of oncogenes and tumor suppressor genes. The book also includes extensive discussion of the practical impact of radiation on everyday life.

Key Features

@introbul:Key Features @bul:* Covers the fundamentals of radiation physics in a manner that is understandable to students and professionals with a limited physics background * Includes problem sets and exercises to aid both teachers and students * Discusses radioactivity, internally deposited radionuclides, and dosimetry * Analyzes the risks for occupational and non-occupational workers exposed to radiation sources


AUDIENCE:Upper-level undergraduate and graduate students in radiological science, biophysics, and nuclear engineering departments; students in DOE courses, and health physics or medical physics courses that require certification training; medical residents in radiology, radiation oncology, and nuclear medicine departments; researchers and professionals working in these fields.

Table of Contents

Introduction: A Historical Perspective. Quantities and Units and Definitions. Electromagnetic Radiation. Radioactivity. Interaction of Radiation with Matter. Energy Transfer Processes. Radiation Chemistry. Theories and Models, Cell Survival. Survival Curve and Its Significance. Modification of Radiation Response. Radiation Biology of Normal and Neoplastic Tissue Systems. Late Effects of Radiation on Normal Tissues--Non Stochastic Effects. Stochastic Effects--Radiation Carcinogenesis. Stochastic Effects, Genetic Effects of Ionizing Radiation. High LET Radiation Effects. Metabolism and Biological Effects of Deposited Radionuclides. Radiation Exposure from Natural Background and other Sources. Appendix. Author Index. Subject Index.


No. of pages:
© 1998
Academic Press
Print ISBN:
Electronic ISBN:

About the author

Edward Alpen

Edward L. Alpen is the recipient of many awards, including the Distinguished Service Medal of the Department of Defense and the Navy Science Medal for Distinguished Achievement in Science. Dr. Alpen has been listed in Leaders in American Science, Marquis' Who's Who in the World of Science, and Marquis' Who's Who in the World. Alpen has also been a member of numerous professional societies,including the Bioelectromagnetic Society, the Royal Society of Medicine, the California Academy of Sciences, the Radiation Research Society, and the British Institute of Radiology. Highlights of Alpen's professional career includes positions as ExecutiveVice President and Chief Technical Officer, Neutron Technology Corporation (1990–1992), Director of the United Kingdom and Ireland Study, Centre of the University of California, London (1988–1990), Chair of the Technical Electronic Products Radiation Safety Standards Commission of the Food and Drug Administration (1977–1980), Director of the Washington State Board of International Trade (1974–1976), Associate Director of the Pacific Northwest Laboratory (1969–1971), and Directorof the Biological and Medical Sciences Division at the Naval Radiological Defense Laboratory (1958–1969). Dr. Alpen currently holds concurrent faculty appointments at the University of California at Berkeley and the University of California School of Medicine, San Francisco.

Affiliations and Expertise

University of California, Berkeley and San Francisco, California, U.S.A.


@from:Praise for the Second Edition @qu:"...the book is well written. One of the attractive parts of the book is that as a single authored volume it is coherent from beginning to end... The book is highly recommended as a text in radiation biophysics and as a reference source for those who are working in closely related areas." @source:--RADIATION RESEARCH @from:Praise for the First Edition @qu:"Radiation Biophysics is a comprehensive textbook that bridges the gap between radiation physics and radiation biology by integrating these fields rather than focusing on one or the other... Radiation Biophysics brings together diverse subject matter in a cogent yet highly readable manner, reflecting the extensive experience of the author as a teacher of this material. The book should also, however, find utility beyond the classroom." @source:--SCIENCE @qu:"I reviewed the first edition of the text for a journal in the discipline of radiation biophysics, and I have referred to the text many times over the past six years... The book is very nicely laid out. It is easy to read and contains extensive author and subject indexes. The illustrations, principally line drawings, are uniformly good... This second edition is improved over the first edition in both appearance and completeness." @source:--William R. Hendee, PhD, Medical College of Wisconsin, for DOODY'S PUBLISHING REVIEWS