Description

Quinones are members of a class of aromatic compounds with two oxygen atoms bonded to the ring as carbonyl groups. This volume covers the role of quinines enzymes in cellular signalling and modulation of gene expression.

Key Features

*Coenzyme Q: Detection and Quinone Reductases *Plasma Membrane Quinone Reductases *Quinones, Cellular Signaling, and Modulation of Gene Expression

Readership

Biochemists, cell biologists, molecular biologists, geneticists, biophysicists

Table of Contents

Coenzyme Q: Detection and Quinone Reductases; Plasma Membrane Quinone Reductases; Quinones, Cellular Signaling, and Modulation of Gene Expression

Details

No. of pages:
421
Language:
English
Copyright:
© 2004
Published:
Imprint:
Academic Press
Print ISBN:
9780121827823
Electronic ISBN:
9780080497167

About the editors

Lester Packer

Lester Packer received a PhD in Microbiology and Biochemistry in 1956 from Yale University. In 1961, he joined the University of California at Berkeley serving as Professor of Cell and Molecular Biology until 2000, and then was appointed Adjunct Professor, Pharmacology and Pharmaceutical Sciences, School of Pharmacy at the University of Southern California. Dr Packer received numerous distinctions including three honorary doctoral degrees, several distinguished Professor appointments. He was awarded Chevalier de l’Ordre National du Merite (Knight of the French National Order of Merit) and later promoted to the rank of Officier. He served as President of the Society for Free Radical Research International (SFRRI), founder and Honorary President of the Oxygen Club of California. He has edited numerous books and published research; some of the most cited articles have become classics in the field of free radical biology: Dr Packer is a member of many professional societies and editorial boards. His research elucidated - the Antioxidant Network concept. Exogenous lipoic acid was discovered to be one of the most potent natural antioxidants and placed as the ultimate reductant or in the pecking order of the “Antioxidant Network” regenerating vitamins C and E and stimulating glutathione synthesis, thereby improving the overall cellular antioxidant defense. The Antioxidant Network is a concept addressing the cell’s redox status. He established a world-wide network of research programs by supporting and co-organizing conferences on free radical research and redox biology in Asia, Europe, and America.