Quantitative Neuroendocrinology, Volume 28

1st Edition

Editor-in-Chiefs: P. Michael Conn
Serial Volume Editors: Michael Johnson Johannes Veldhuis
Hardcover ISBN: 9780121852986
eBook ISBN: 9780080536477
Imprint: Academic Press
Published Date: 20th September 1995
Page Count: 433
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Table of Contents

Evolution of Deconvolution Analysis as a Hormone Pulse Detection Method, M.L. Johnson and J.D. Veldhuis. Specific Methodological Approaches to Selected Contemporary Issues in Deconvolution Analysis of Pulsatile Neuroendocrine Data, J.D. Veldhuis and M.L. Johnson. Physiological within subject Variability and Test-Retest Reliability of Deconvolution Analysis of Luteinizing Hormone Release, T. Mulligan, M.L. Johnson, and J.D. Veldhuis. Methods for Validating Deconvolution Analysis of Pulsatile Hormone Release: Luteinizing Hormone as a Paradigm, T. Mulligan, M.L. Johnson, and J.D. Veldhuis. Complicating Effects of Highly Correlated Model Variables on Nonlinear Least-Squares Estimates of Unique Parameter Values and Their Statistical Confidence Intervals: Estimating Basal Secretion and Neurohormone Half-Life by Deconvolution Analysis, J.D. Veldhuis, W.S. Evans, and M.L. Johnson. Techniques for Assessing Ultradian Rhythms in Hormonal Secretion, J. Sturis and E. Van Cauter. Frequency Domain Analysis of High-Frequency Ultradian Plasma Adrenocorticotripic Hormone and Glucocorticoid Fluctuations, M. Carnes and B. Goodman. Monitoring Dynamic Responses of Perifused Neuroendocrine Tissues to Stimuli in Real Time, A.R. Midgley, R.M. Brand, P.A. Favreau, B.G. Boving, M.N. Ghazzi, V. Padmanabhan, E.Y. Young, and H.C. Cantor. Realistic Emulation of Highly Irregular Temporal Patterns of Hormone Release: A Computer-Based Pulse Simulator, M. Staume, M.L. Johnson, and J.D. Veldhuis. Simulation of Peptide Prohormone Processing and Peptidergic Granule Transport and Release in Neurosecretory Cells, D.K. Hartline, R.W. Newcomb, and R.W. Newcomb. Systems-Level Analysis of Physiological Regulatory Interactions Controlling Complex Secretory Dynamics of the Growth Hormone Axis: A


In this volume contemporary methods designed to provide insights into, mathematical structure for, and predictive inferences about neuroendocrine control mechanisms are presented.

Key Features

@introbul:Key Features @bul:* Collates an array of contemporary techniques for analysis of neuroendocrine data

  • Discusses current problems in and solutions to neurohormone pulse analysis
  • Identifies relevant software available


No. of pages:
© Academic Press 1995
Academic Press
eBook ISBN:
Hardcover ISBN:

About the Editor-in-Chiefs

P. Michael Conn Editor-in-Chief

P. Michael Conn is the Senior Vice President for Research and Associate Provost, Texas Tech Health Sciences Center. He is The Robert C. Kimbrough, Professor of Internal Medicine and Cell Biology/Biochemistry. He was previously Director of Research Advocacy and Professor of Physiology and Pharmacology, Cell Biology and Development and Obstetrics and Gynecology at Oregon Health and Science University and Senior Scientist of the Oregon National Primate Research Center (ONPRC). He served for twelve years as Special Assistant to the President and Associate Director of the ONPRC. After receiving a B.S. degree and teaching certification from the University of Michigan (1971), a M.S. from North Carolina State University (1973), and a Ph.D. degree from Baylor College of Medicine (1976), Conn did a fellowship at the NIH, then joined the faculty in the Department of Pharmacology, Duke University Medical Center where he was promoted to Associate Professor in 1982. In 1984, he became Professor and Head of Pharmacology at the University of Iowa College of Medicine, a position he held for eleven years. Conn is known for his research in the area of the cellular and molecular basis of action of gonadotropin releasing hormone action in the pituitary and therapeutic approaches that restore misfolded proteins to function. His work has led to drugs that have benefitted humans and animals. Most recently, he has identified a new class of drugs, pharmacoperones, which act by regulating the intracellular trafficking of receptors, enzymes and ion channels. He has authored or co-authored over 350 publications in this area and written or edited over 200 books, including texts in neurosciences, molecular biology and endocrinology. Conn has served as the editor of many professional journals and book series (Endocrinology, Journal of Clinical Endocrinology and Metabolism, Endocrine, Methods, Progress in Molecular Biology and Translational Science and Contemporary Endocrinology). Conn serve

Affiliations and Expertise

Texas Tech University Health Sciences Center, Lubbock, USA

About the Serial Volume Editors

Michael Johnson Serial Volume Editor

Affiliations and Expertise

University of Virginia Health Sciences Center, Charlottesville, USA

Johannes Veldhuis Serial Volume Editor

Affiliations and Expertise

University of Virginia Health Sciences Center, Charlottesville, U.S.A.