Description

Here is an invaluable new book on quantitative gas chromatography which explains how the method can - or should - be used for accurate and precise analysis. Gas chromatography is firmly established as one of the few major methods for the quantitative analysis of complex mixtures. It is fast, accurate and inexpensive, with a broad range of applications. It has however become very complex and involved: over 200 stationary phases, more than 10 detector principles and several very different column types are available from among the catalogs of over 100 manufacturers and major retailers. The progressive changes in the nature of gas chromatography have created new needs for information which are not satisfied by the literature presently available. This book provides a complete discussion of all the problems involved in the achievement of quantitative analysis by gas chromatography, whether in the research laboratory, in the routine analysis laboratory or in process control. For this reason the presentation of theoretical concepts has been limited to the essential, while extensive explanations have been devoted to the various steps involved in the derivation of precise and accurate data. This starts with the selection of the instrumentation and column, continues with the choice of optimum experimental conditions, then calibration and ends with the use of correct procedures for data acquisition and calculations. Finally, there is almost always a way to reduce errors and an entire chapter deals with this single issue. Numerous relevant examples are presented. The first part of the book presents the theoretical background, simple enough to be understood by all analytical chemists, but still complete and up-to-date. It discusses the problems of flow dynamics, retention and band broadening. The changes in band profile associated with column overloading are explained without much recourse to mathematics. The second part describes

Table of Contents

1. Introduction and Definitions. 2. Fundamentals of the Chromatographic Process. Flow of Gases through Chromatographic Columns. 3. Fundamentals of the Chromatographic Process. The Thermodynamics of Retention in Gas Chromatography. 4. Fundamentals of the Chromatographic Process. Chromatographic Band Broadening. 5. Fundamentals of the Chromatographic Process. Column Overloading. 6. Methodology. Optimization of the experimental conditions of a chromatographic separation using packed columns. 7. Methodology. Advanced Packed Columns. 8. Methodology. Open Tubular Columns. 9. Methodology. Gas Chromatographic Instrumentation. 10. Detectors for Gas Chromatography. 11. Qualitative Analysis by Gas Chromatography. 12. Qualitative analysis. Hyphenated Techniques. 13. Quantitative Analysis by Gas Chromatography. Basic Problems, Fundamental Relationships, Measurement of the Sample Size. 14. Quantitative Analysis by Gas Chromatography. 15. Quantitative analysis by Gas Chromatography. Measurement of Peak Area and Derivation of Sample Composition. 16. Quantitative Analysis by Gas Chromatography. Source of Errors, Accuracy and Precision of Chromatographic Measurements. 17. Applications to Process Control Analysis. Appendix: Chromatography Lexicon. Subject Index.

Details

No. of pages:
796
Language:
English
Copyright:
© 1988
Published:
Imprint:
Elsevier Science
eBook ISBN:
9780080858470
Print ISBN:
9780444428578

About the authors