Quantification of Brain Function Using PET - 1st Edition - ISBN: 9780123897602, 9780080540108

Quantification of Brain Function Using PET

1st Edition

Serial Editors: Ralph Myers Vin Cunningham Dale Bailey
eBook ISBN: 9780080540108
Imprint: Academic Press
Published Date: 9th July 1996
Page Count: 443
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Description

Functional imaging of the brain is one of the most rapidly advancing areas of neuroscience and Positron Emission Tomography (PET) plays a major role in this progress. This book provides a comprehensive overview of the current status of PET and state-of-the-art neuroimaging. It is comprised of summaries of the presentations by experts in the field. Topics covered include radiotracer selection, advances in instrumentation, image reconstruction and data analysis, and statistical mapping of brain activity. This book focuses on the accuracy of the functional image and the strategies for addressing clinical, scientific, and diagnostic questions.

Key Features

Covers the PET imaging process from tracer selection to analysis and interpretation Contains 79 concise reports with abundant illustrations The definitive state-of-the-art book for functional neuroscience with PET

Readership

Ideal for researchers and students in neuroscience, neurology, neuropsychology, and biophysics.

Table of Contents

Tracer Selection: M.R. Kilbourn,<$> In Vivo-In Vitro<$> Correlations: An Example from Vesicular Monoamine Transporters. W.D. Brown, O.T. DeJesus, S.E. Shelton, H. Uno, D. Houser, R.J. Nickles, S.J. Swerdloff, A. Roberts, E. Baker, and J.E. Holden,<$> The Noncatechol Tracer 6-flouro-m-tyrosine: Extrastriatal Distribution of Dopaminergic Function. R. Myers, S.P. Hume, S. Ashworth, A.A. Lammertsma, P.M. Bloomfield, S. Rajeswaran, and T. Jones,<$> Quantification of Dopamine Receptors and Transporter in Rat Striatum Using a Small Animal PET Scanner. W.-D. Heiss, K. Wienhard, R. Graf, J. Lottgen, U. Pietrzyk, and R. Wagner, <$>Applicability of Experimental PET in Animal Models for the Interpretation of Incidental Findings in Human Stroke. A. Malizia, G. Forse, R.N. Gunn, A. Haida, L. Schnorr, S. Rajeswaran, K. Poole, D. Nutt, and T. Jones,<$> The MOC Counter--A Pharmacological Tool for the in Vivo<$> Measurement of Ligand Occupancy Indices in the Human Brain. A. Biegon, C. Mathis, and W. Jagust,<$> Autoradiography As a Tool for PET/SPECT Tracer Selection and Assessment. S. Osman, J.A. McCarron, S.P. Hume, S. Ashworth, V.W. Pike, S.K. Luthra, A.A. Lammertsma, C. Bench, P. Grasby, I.A. Cliffe, and A.Fletcher, <$>Radioactive Metabolites of the 5-HT<->1A<$> Receptor Radioligand, [O-methyl<$>-<+>11<$>C]WAY-100635, in Humans. D.F. Smith, R. Glaser, A. Gee, and A. Gjedde,<$> <+>11<$>C-Nefopam as a Potential PET Tracer of Serotonin Reuptake Sites: Initial Findings in Living Pig Brain. A.D. Gee, N. Gillings, D. Smith, O. Inoue, K. Kobayashi, and A. Gjedde,<$> The Effect of Amine pKa on the Transport and Binding of Amphetamine Analogues in Pig Brain: An in Vivo<$> Comparison of B, B-Difluoro[N-methyl<+>11C]methamphetamine Using PET. M.R. Kilbourn,<$> Tacer Selection Summary. Data Acquisition:<$> S.R. Meikle, S. Eberl, B.F. Hutton, P.K. Hooper, and M.J. Fulham,<$> Application of Simultaneous Emission and Transmission Scanningto Quantitative Cerebral PET. H. Iida, S. Miura, I. Kanno, T. Ogawa, and K. Uemura,<$> A New PET Camera for Noninvasive Quantitation of Physiological Functional Parametric Images: HEADTOME-V-DUAL. S. Ashworth, A. Ranicar, P.M. Bloomfield, T. Jones,and A.A. Lammertsma,<$> Development of an On-Line Blood Detector System for PET Studies in Small Animals. M. Itoh, H. Watabe, M. Miyake, S. Hagisawa, T. Fujiwara, R. Iwata, T. Ido, and T. Nakamura,<$> Noninvasive Determination of Arterial Input of <+>15<$>O Tracers Using a Dual Cutaneous B-Detector Set above the Radial Artery. M. Vafaee, K. Murase, A. Gjedde, and E. Meyer, <$>Dispersion Correction for Automatic Sampling of O-15 Labeled H<->2<$>O and Red Blood Cells. D.W. Townsend, J.C. Price, B.J. Lopresti, M.A. Mintun, P.E. Kinahan, F. Jadali, S. Sashin, N.R. Simpson, and C. A. Mathis, <$>Scatter Correction for Brain Receptor Quantitation in 3D PET. J.S. Rakshi, D.L. Bailey, P.K. Morrish, and D.J. Brooks,<$> Implementation of 3D Acquisition,Reconstruction and Analysis of Dynamic <+>18<$>F Fluorodopa Studies. R. Trebossen, B. Bendriem, A. Fontaine, V. Frouin, and P. Remy,<$> Quantitation of the [<+>18<$>F]Fluorodopa Uptake in the Human Striata in 3D PET with the ETM Scatter Correction. S. Holm, I. Law, and O.B. Paulson,<$> 3D PET Activation Studies with H<->2<$><+>15<$>O Bolus Injection: Count Rate Performance and Dose Optimization. N. Sadato, R.E. Carson, M.E. Daube-Witherspoon, G. Campbell, M. Hallett, and P. Herscovitch,<$> Optimization of Noninvasive Activation Studies with O-15-Water and 3D PET. L. Eriksson,<$>Data Acquisition Summary. Data Processing:<$> J.T. Yap, C.-M. Kao, M. Cooper, C.-T. Chen, and M. Wernick,<$> Sinogram Recovery of Dynamic PET Using Principal Component Analysis and Projections onto Convex Sets. B.A. Ardekani, M. Braun, B.F. Hutton, and I. Kanno,<$> Minimum Cross Entropy Reconstruction of PET Images Using Prior Anatomical Information Obtained from MR. B. Lipinski, H. Herzog, E.R. Kops, W. Oberschelp, H.W. Muller-Gartner,<$> MR Guided PET Reconstruction and Problems with Anatomical Misinformation. A.C. Evans, D.L. Collins, and C.J. Holmes,<$> Automatic 3D Regional MRI Segmentation and Statistical Probability Anatomy Maps. A.Z. Snyder,<$> Difference Image vs Ratio Image Error Function Forms in PET-PET Realignment. W.D. Brown, R. Pyzalski, M. Crossnoe, S.J. Swerdloff, and J.E. Holden,<$> Tailored Coregistration of Striata for Dopaminergic PET. D. Berdichevsky, Z. Levin, E.D. Morris,and N.M. Alpert, <$>Optimization of PET_MRI Image Registration. S.-C. Huang, J. Yang, M. Dahlbom, C. Hoh, J. Czernin, Y. Zhou, and D.C. Yu,<$> Feature-Matching Axial Averaging Method for Enhancing Signal-to-Noise Ratio of Images Generated by New Generation PET Scanners. J.J. Frost, C.C. Meltzer, J.K. Zubieta, J.M. Links, P. Brakeman, M.J. Stumpf, and M. Kruger,<$> MR-Based Correction of Partial Volume Effects in Brain PET Imaging. O.G. Rousset, Y. Ma, S. Marenco, D.F. Wong, and A.C. Evans,<$> In Vivo<$> Correction Method for Partial Volume Effects in Positron Emission Tomography: Accuracy and Precision. Y. Kosugi, M. Sase, Y. Suganami, T. Momose, and J. Nishikawa,<$> Dissolution of Partial Volume Effect in PET by An Inversion Technique with the MR-Embedded Neural Network Model. G. Blomqvist, L.Eriksson, and G. Rosenqvist,<$> The Effect of Spatial Correlation on the Quantification in Positron Emission Tomography. K. Herholz, S. Dickhoven, H. Karbe, M. Halber, U. Pietrzyk, and W.-D.Heiss,<$> Integrated Quantitative Analysis of Functional and Morphological 3D Data by Volumes of Interest. S.C. Strother,<$> Data Processing Summary. Part IV: Kinetic Analysis:<$> R.E. Carson, Y. Yan, and R. Shrager,<$> Absolute Cerebral Blood Flow with <+>15<$>O-Water and PET: Determination without a Measured Input Function.

Details

No. of pages:
443
Language:
English
Copyright:
© Academic Press 1996
Published:
Imprint:
Academic Press
eBook ISBN:
9780080540108

About the Serial Editor

Ralph Myers

Affiliations and Expertise

MRC Medical Sciences Center, Royal Postgraduate Medical School, Hammersmith Hospital

Vin Cunningham

Affiliations and Expertise

MRC Medical Sciences Center, Royal Postgraduate Medical School, Hammersmith Hospital

Dale Bailey

Affiliations and Expertise

MRC Medical Sciences Center, Royal Postgraduate Medical School, Hammersmith Hospital