Pyruvate and Fatty Acid Metabolism

Pyruvate and Fatty Acid Metabolism

1st Edition - January 1, 1971

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  • Editors: Marcel Florkin, Elmer H. Stotz
  • eBook ISBN: 9781483193168

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Comprehensive Biochemistry, Volume 18S: Pyruvate and Fatty Acid Metabolism focuses on the processes, methodologies, principles, and reactions involved in pyruvate and fatty acid metabolism, including broad outlines of the metabolism of amino acids, proteins, carbohydrates, lipids, and their derived products. The selection first ponders on pyruvate dehydrogenase complex and citric acid cycle. Numerical analyses of the various reaction sequences are presented. The text also takes a look at fatty acid metabolism. Discussions focus on fatty acid oxidation and biosynthesis, elongation and desaturation of fatty acids, and control of fatty acid oxidation and biosynthesis. The book is a valuable reference for researchers interested in pyruvate and fatty acid metabolism.

Table of Contents

  • General Preface

    Preface to Section IV

    Chapter I. The Pyruvate Dehydrogenase Complex and the Citric Acid Cycle

    1. Pyruvate Dehydrogenase

    a. Mechanism

    b. Control of Pyruvate Oxidation

    2. Citric Acid Cycle

    a. Introduction

    b. Intracellular Compartmentation of Enzymes of the Citric Acid Cycle

    c. Compartmentation of some Enzymes Ancillary to the Citric Acid Cycle

    d. Permeability of Mitochondria to Substrates of the Citric Acid Cycle


    Chapter II. Fatty Acid Metabolism

    1. Introduction

    2. Fatty Acid Oxidation

    a. β-Oxidation of Saturated Acids

    b. β-Oxidation of Unsaturated Fatty Acids

    c. The Oxidation of Odd-Chain Fatty acids

    3. Fatty Acid Biosynthesis

    a. Acetyl-CoA Carboxylase

    b. Fatty Acid Synthetases

    c. Acyl Carrier Protein

    d. The Enzymes of Fatty Acid Synthesis

    e. Multienzyme Complex of Fatty Acid Synthetase

    4. Elongation of Fatty Acids

    a. Microsomal System for Elongation

    b. Mitochondrial System for Elongation

    5. Desaturation of Fatty Acids

    6. α-Oxidation of Fatty Acids

    7. ω-Oxidation of Fatty Acids

    8. Ketone Body Formation

    9. Control of Fatty Acid Biosynthesis

    a. Regulation of Fatty Acid Synthesis by Metabolites

    b. Regulation of Fatty Acid Synthesis by Enzyme Synthesis

    10. Control of Fatty Acid Oxidation


    Subject Index

Product details

  • No. of pages: 126
  • Language: English
  • Copyright: © Elsevier 1971
  • Published: January 1, 1971
  • Imprint: Elsevier
  • eBook ISBN: 9781483193168

About the Editors

Marcel Florkin

Elmer H. Stotz

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