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Proteins in Biology and Medicine contains the proceedings of the 1981 U.S.-China Conference on Proteins in Biology and Medicine, held in Shanghai, China. The papers explore the structure-function relationships of proteins, including their regulatory properties. Topics range from the regulation of biological processes to the structure-function relationships of enzymes and blood proteins, along with protein-protein interactions. Organized into four sections encompassing 23 chapters, this book begins with an overview of structure-function relationships in phospholipase A2, including the enzyme found in snake venom. It then discusses the suicide substrates for specific target enzymes, the conformation of proteins and peptides in solution, the serum lipoproteins and their relationship to atherosclerosis, the abnormal hemoglobin in the Chinese population, and the mung bean trypsin inhibitor. Moreover, the book explains the streptokinase-plasminogen interaction and the molecular localization of protein-protein interaction sites in the lactose synthase system. The final chapter analyzes the structure and biological activities of plant lectins. This book will be of interest to biochemists, microbiologists, molecular biologists, and biophysicists.
1. Regulation of Biological Processes
Structure, Function, and Evolution of Insulin-Related Polypeptides
The Semisynthesis of Insulin and Its Analogs
Studies on the Three-Dimensional Structure of Insulin and Its Analogs
Role of Cell Surface Components and Receptors in Thrombin-Stimulated Cell Division
A Cancer Suppressive Factor in Biological Fluids
Isolation and Characterization of Human Lymphokines
Bioactive Factors of the Blood Complement System
Modulation of Primary Structure in Control and Secretion of Proteins
2. Structure and Function Relationships of Enzymes
Structure-Function Relationships in Phospholipases A2
Studies of Snake Venom Enzymes: Phospholipase A2 and a Fibrinolytic Enzyme
Suicide Substrates for Specific Target Enzymes
Properties, Function, and Localization of Two Cytochromes P-450 from Liver and Kidney
Studies on Glucoamylase from Monascus rubiginosus Sato
Role of Cys-149 in Ligand Binding and the Formation of a Fluorescent Derivative at the Active Site of D-Glyceraldehyde-3-phosphate Dehydrogenase
Recent Studies on the Conformation of Proteins and Peptides in Solution
X-Ray Crystallographic Studies of the Structure, Function, and Evolution of Proteins
3. Structure and Function Relationships of Blood Proteins
Studies on Serum Lipoproteins: Structure, Function, Metabolism, and Their Relationship to Atherosclerosis
The Biosynthesis of Fibrinogen and the Cloning of Its cDNA
Structural Analyses of Abnormal Hemoglobins in Chinese
4. Protein-Protein Interactions
Studies on the Mung Bean Trypsin Inhibitor
The Streptokinase-Plasminogen Interaction: A Model of Binding Activation of Serine-Protease Zymogens
Studies of the Molecular Localization of Protein-Protein Interaction Sites in the Lactose Synthase System
The Structure and Biological Activities of Plant Lectins
- No. of pages:
- © Academic Press 1982
- 28th January 1982
- Academic Press
- eBook ISBN:
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