Protein Modules and Protein-Protein Interactions - 1st Edition - ISBN: 9780120342617, 9780080493756

Protein Modules and Protein-Protein Interactions, Volume 61

1st Edition

Serial Volume Editors: Joël Janin
Hardcover ISBN: 9780120342617
eBook ISBN: 9780080493756
Imprint: Academic Press
Published Date: 12th November 2002
Page Count: 333
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Table of Contents

Protein Modules and Protein-Protein Interaction: Toward a Global View Structural Basis for Affinity and Specificity in Macromolecular Recognition Sequence Analysis of Multidomain Proteins: Past Perspectives and Future Directions Identification of Transiently Interacting Proteins and of Stable Protein Complexes Molecular Recognition in Antibody-Antigen Complexes Molecular Recognition by SH2 Domains How SH3 Domains Recognize Proline Structural Biology of eIF4F: mRNA Recognition and Preparation in Eukaryotic Translation Initiation


Protein modules engage in a multitude of interactions with one another and with other cellular components, notably with DNA. These interactions are a central aspect of protein function of great relevance in the post-genomic era. This volume describes a panel of approaches for analyzing protein modules and their interactions, ranging from bioinformatics to physical chemistry, to biochemistry, with an emphasis on the structure-function relationship in protein-protein complexes involved in cellular processes including signal transduction.

Key Features

Key Features

  • Comprehensive overview of different facets of macromolecule interactions
  • Computational and bioinformatics aspects of analyzing protein modules and their interactions
  • Emphasis on structure-function relationship in protein-protein complexes involved in cellular processes


Biochemists, biophysicists, molecular biologists, immunologists


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© Academic Press 2003
Academic Press
eBook ISBN:
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@from:PRAISE FOR THE SERIES @qu:"The authority, originality, and editing of the reviews are first class." @source:—NATURE @qu:"The Advances in Protein Chemistry series has been a major factor in the education of protein chemists." @source:—JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

About the Serial Volume Editors

Joël Janin Serial Volume Editor

Affiliations and Expertise

Laboratoire d'Enzymologie et Biochemie Structurales, France