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Protein Modules and Protein-Protein Interaction: Toward a Global View Structural Basis for Affinity and Specificity in Macromolecular Recognition Sequence Analysis of Multidomain Proteins: Past Perspectives and Future Directions Identification of Transiently Interacting Proteins and of Stable Protein Complexes Molecular Recognition in Antibody-Antigen Complexes Molecular Recognition by SH2 Domains How SH3 Domains Recognize Proline Structural Biology of eIF4F: mRNA Recognition and Preparation in Eukaryotic Translation Initiation
Protein modules engage in a multitude of interactions with one another and with other cellular components, notably with DNA. These interactions are a central aspect of protein function of great relevance in the post-genomic era. This volume describes a panel of approaches for analyzing protein modules and their interactions, ranging from bioinformatics to physical chemistry, to biochemistry, with an emphasis on the structure-function relationship in protein-protein complexes involved in cellular processes including signal transduction.
- Comprehensive overview of different facets of macromolecule interactions
- Computational and bioinformatics aspects of analyzing protein modules and their interactions
- Emphasis on structure-function relationship in protein-protein complexes involved in cellular processes
Biochemists, biophysicists, molecular biologists, immunologists
- No. of pages:
- © Academic Press 2003
- 12th November 2002
- Academic Press
- Hardcover ISBN:
- eBook ISBN:
PRAISE FOR THE SERIES:
"The authority, originality, and editing of the reviews are first class." --NATURE
"The Advances in Protein Chemistry series has been a major factor in the education of protein chemists." --JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Laboratoire d'Enzymologie et Biochemie Structurales, France