This is the first compilation of protein lipidation enzymes. This volume summarizes recent dramatic developments regarding enzymes responsible for protein lipidation, a process critical for a number of physiological functions, including cell proliferation and morphology. Inhibitors of protein lipidation have recently been shown to be useful as anticancer drugs. Enzymatic mechanisms, mutational analysis, and structural studies are presented.
@introbul:Key Features @bul:* The enzymatic mechanisms of protein lipidation
- Three-dimensional structures of protein farnesytransferase, protein geranylgeranytransferase II, and n-myristoryltransferase
Biochemists, molecular biologists, biotechnologists, researchers in biomedical and in pharmaceutical research, physiologists.
- No. of pages:
- © Academic Press 2001
- 17th October 2000
- Academic Press
- eBook ISBN:
- Hardcover ISBN:
Professor Fuyu Tamanoi works at the Dept. of Microbiology, Immunology and Molecular Genetics at the University of California.
University of California, Los Angeles, USA
University of California School of Medicine, Los Angeles, California, U.S.A.