Description

Protein-lipid interactions as a field of study is now a mature area, and this volume of New Comprehensive Biochemistry has been published with two objectives in mind. Firstly, to look to the future, and try to envisage how the subject may develop in the near to medium future. Secondly, to present contrasting or complementary views on the same system. For example, the acetylcholine receptor is discussed from a predominantly structural aspect by Barrantes, and from the kinetic standpoint by Rankin, et al.

The volume not only gives an update on specific aspects of the field, but also shows the way in which the phenomenon of protein-lipid interactions is now seemingly infiltrating many areas of biomembrane research, from recombinant DNA studies, protein insertion and assembly and reconstitution considerations to structural studies of membrane proteins.

Table of Contents

(a full list of contents is available from the Publisher on request). Preface. List of Contributors. Chapter 1. Protein-lipid interactions and membrane heterogeneity (O.G. Moutitsen, R.L. Biltonen). 2. The nature of the lipid-protein interface and the influence of protein structure on protein-lipid interactions (D. Marsh). 3. Cooperative regulation of membrane enzymes by lipids (H. Sandermann Jr., T.M. Duncan, J.O. McIntyre, S. Fleischer). 4. Lipid-protein interaction in a biological membrane: Effect of cholesterol and acyl chain degree of unsaturation (C.E. Castuma, M.T. Lamy-Freund, R.R. Brenner, S. Schreier). 5. Lipid-peptide interactions in model systems: Membrane insertion and translocation of peptides (A.I.P.M. de Kroon, J. de Gier, B. de Kruijff). 6. Protein-lipid interactions with peripheral membrane proteins (M.B. Sankaram, D. Marsh). 7. Genetic studies on the functions of membrane-forming phospholipids (T.P. McGee, M.K.Y. Fung, V.A. Bankaitis). 8. Lipid-protein interactions involved in bacteriophage M13 infection (M.A. Hemminga, J.C. Sanders, C.J.A.M. Wolfs, R.B. Spruijt). 9. Functional aspects of acetylcholine receptor-lipid interactions (S.E. Rankin, D.E. Raines, L.A. Dalton, K.W. Miller). 10. The lipid annulus of the nicotinic acetylcholine receptor as a locus of structural-functional interactions (F.J. Barrantes). 11. The (Ca2+-Mg2+)-ATPase and other membrane proteins: what reconstitution tells us about the biological membrane (A.G. Lee, J.M. East). 12. The functional effects of protein and lipid dynamics in sarcoplasmic reticulum (D.D. Thomas, J.E. Mahaney). 13. Infrared spectroscopic studies of lipid-protein interactions in membranes (J.L.R. Arrondo, F.M. Goñi). 14. Lipid-protein interactions in controlled membrane protein array and crys

Details

No. of pages:
378
Language:
English
Copyright:
© 1993
Published:
Imprint:
Elsevier Science
Print ISBN:
9780444815750
Electronic ISBN:
9780080860855

About the editor

Anthony Watts

Affiliations and Expertise

University of Oxford, UK