Progress in Nucleic Acid Research and Molecular Biology

Progress in Nucleic Acid Research and Molecular Biology

1st Edition - October 17, 2008

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  • Editor: P. Michael Conn
  • eBook ISBN: 9780080923277
  • Hardcover ISBN: 9780123745491

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Description

Nucleic acids are the fundamental building blocks of DNA and RNA and are found in virtually every living cell. Molecular biology is a branch of science that studies the physicochemical properties of molecules in a cell, including nucleic acids, proteins, and enzymes. Increased understanding of nucleic acids and their role in molecular biology will further many of the biological sciences, including genetics, biochemistry, and cell biology. Progress in Nucleic Acid Research and Molecular Biology is intended to bring to light the most recent advances in these overlapping disciplines with a timely compilation of reviews comprising each volume.

Key Features

* This series provides a forum for discussion of new discoveries, approaches, and ideas
* Contributions from leading scholars and industry experts
* Reference guide for researchers involved in molecular biology and related fields

Readership

Researchers in molecular biology, biochemistry, cell biology, and genetics

Table of Contents

  • Table of Contents
    Progress in Nucleic Acid Research and Molecular Biology
    Molecular Biology of Protein Folding, Part A
    Chapter 1
    Fly orthologs of human diseases
    Lawrence T. Reiter
    Chapter 2
    FCS-FRET in nucleic acid conformation
    Marica Levitus
    Chapter 3
    Intron modeling
    Dinggeng Chai
    Chapter 4
    Visualization of translocation
    Stephen Kowalszykowski
    Chapter 5
    The role of DNA polymerase epsilon
    Thomas A. Kunkel
    Chapter 6
    Conformational switching
    Maumita Mandal
    Chapter 7
    Site-directed spin labeling
    Peter Z. Qin
    Chapter 8
    DNA computing and robotics
    Milan Stojanovic
    Chapter 9
    Membrane targeting of translating ribosomes
    Wolfgang Wintermeyer
    Chapter 10
    VS ribozyme
    David Lilley
    Chapter 11
    RNA polymerase II complexes
    Guillermo Calero
    Chapter 12
    Epigenic Features of Promoters
    Paul A. Wade
    Chapter 13
    Molecular colony technique: a new tool
    for biomedical research and clinical practice
    Alexander B. Chetverin

Product details

  • No. of pages: 272
  • Language: English
  • Copyright: © Academic Press 2008
  • Published: October 17, 2008
  • Imprint: Academic Press
  • eBook ISBN: 9780080923277
  • Hardcover ISBN: 9780123745491

About the Editor

P. Michael Conn

P. Michael Conn is the Senior Vice President for Research and Associate Provost, Texas Tech Health Sciences Center. He is The Robert C. Kimbrough, Professor of Internal Medicine and Cell Biology/Biochemistry. He was previously Director of Research Advocacy and Professor of Physiology and Pharmacology, Cell Biology and Development and Obstetrics and Gynecology at Oregon Health and Science University and Senior Scientist of the Oregon National Primate Research Center (ONPRC). He served for twelve years as Special Assistant to the President and Associate Director of the ONPRC. After receiving a B.S. degree and teaching certification from the University of Michigan (1971), a M.S. from North Carolina State University (1973), and a Ph.D. degree from Baylor College of Medicine (1976), Conn did a fellowship at the NIH, then joined the faculty in the Department of Pharmacology, Duke University Medical Center where he was promoted to Associate Professor in 1982. In 1984, he became Professor and Head of Pharmacology at the University of Iowa College of Medicine, a position he held for eleven years. Conn is known for his research in the area of the cellular and molecular basis of action of gonadotropin releasing hormone action in the pituitary and therapeutic approaches that restore misfolded proteins to function. His work has led to drugs that have benefitted humans and animals. Most recently, he has identified a new class of drugs, pharmacoperones, which act by regulating the intracellular trafficking of receptors, enzymes and ion channels. He has authored or co-authored over 350 publications in this area and written or edited over 200 books, including texts in neurosciences, molecular biology and endocrinology. Conn has served as the editor of many professional journals and book series (Endocrinology, Journal of Clinical Endocrinology and Metabolism, Endocrine, Methods, Progress in Molecular Biology and Translational Science and Contemporary Endocrinology). Conn served on the National Board of Medical Examiners, including two years as chairman of the reproduction and endocrinology committee. The work of his laboratory has been recognized with a MERIT award from the NIH, the J.J. Abel Award of the American Society for Pharmacology and Experimental Therapeutics, the Weitzman, Oppenheimer and Ingbar Awards of the Endocrine Society, the National Science Medal of Mexico (the Miguel Aleman Prize) and the Stevenson Award of Canada. He is the recipient of the Oregon State Award for Discovery, the Media Award of the American College of Neuropsychopharmacology and was named a distinguished Alumnus of Baylor College of Medicine in 2012. Conn is a previous member of Council for the American Society for Cell Biology and the Endocrine Society and is a prior President of the Endocrine Society, during which time he founded the Hormone Foundation and worked with political leadership to heighten the public’s awareness of diabetes. Conn’s students and fellows have gone on to become leaders in industry and academia. He is an elected member of the Mexican Institute of Medicine and a fellow of the American Association for the Advancement of Science. He is the co-author of The Animal Research War (2008) and many articles for the public and academic community on the value of animal research and the dangers posed by animal extremism. His op/eds have appeared in The Washington Post, The LA Times, The Wall Street Journal, the Des Moines Register, and elsewhere. Conn consults with organizations that are influenced by animal extremism and with universities and companies facing challenges from these groups.

Affiliations and Expertise

Texas Tech University Health Sciences Center, Lubbock, USA

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