Description

Nucleic acids are the fundamental building blocks of DNA and RNA and are found in virtually every living cell. Molecular biology is a branch of science that studies the physicochemical properties of molecules in a cell, including nucleic acids, proteins, and enzymes. Increased understanding of nucleic acids and their role in molecular biology will further many of the biological sciences, including genetics, biochemistry, and cell biology. Progress in Nucleic Acid Research and Molecular Biology is intended to bring to light the most recent advances in these overlapping disciplines with a timely compilation of reviews comprising each volume.

Key Features

* This series provides a forum for discussion of new discoveries, approaches, and ideas * Contributions from leading scholars and industry experts * Reference guide for researchers involved in molecular biology and related fields

Readership

Researchers in molecular biology, biochemistry, cell biology, and genetics

Table of Contents

Table of Contents Progress in Nucleic Acid Research and Molecular Biology Molecular Biology of Protein Folding, Part A Chapter 1 Fly orthologs of human diseases Lawrence T. Reiter Chapter 2 FCS-FRET in nucleic acid conformation Marica Levitus Chapter 3 Intron modeling Dinggeng Chai Chapter 4 Visualization of translocation Stephen Kowalszykowski Chapter 5 The role of DNA polymerase epsilon Thomas A. Kunkel Chapter 6 Conformational switching Maumita Mandal Chapter 7 Site-directed spin labeling Peter Z. Qin Chapter 8 DNA computing and robotics Milan Stojanovic Chapter 9 Membrane targeting of translating ribosomes Wolfgang Wintermeyer Chapter 10 VS ribozyme David Lilley Chapter 11 RNA polymerase II complexes Guillermo Calero Chapter 12 Epigenic Features of Promoters Paul A. Wade Chapter 13 Molecular colony technique: a new tool for biomedical research and clinical practice Alexander B. Chetverin

Details

No. of pages:
272
Language:
English
Copyright:
© 2008
Published:
Imprint:
Academic Press
Print ISBN:
9780123745491
Electronic ISBN:
9780080923277

About the editor

P. Michael Conn

P. Michael Conn is the Senior Vice President for Research and Associate Provost, Texas Tech Health Sciences Center. He is The Robert C. Kimbrough, Professor of Internal Medicine and Cell Biology/Biochemistry. He was previously Director of Research Advocacy and Professor of Physiology and Pharmacology, Cell Biology and Development and Obstetrics and Gynecology at Oregon Health and Science University and Senior Scientist of the Oregon National Primate Research Center (ONPRC). He served for twelve years as Special Assistant to the President and Associate Director of the ONPRC. After receiving a B.S. degree and teaching certification from the University of Michigan (1971), a M.S. from North Carolina State University (1973), and a Ph.D. degree from Baylor College of Medicine (1976), Conn did a fellowship at the NIH, then joined the faculty in the Department of Pharmacology, Duke University Medical Center where he was promoted to Associate Professor in 1982. In 1984, he became Professor and Head of Pharmacology at the University of Iowa College of Medicine, a position he held for eleven years. Conn is known for his research in the area of the cellular and molecular basis of action of gonadotropin releasing hormone action in the pituitary and therapeutic approaches that restore misfolded proteins to function. His work has led to drugs that have benefitted humans and animals. Most recently, he has identified a new class of drugs, pharmacoperones, which act by regulating the intracellular trafficking of receptors, enzymes and ion channels. He has authored or co-authored over 350 publications in this area and written or edited over 200 books, including texts in neurosciences, molecular biology and endocrinology. Conn has served as the editor of many professional journals and book series (Endocrinology, Journal of Clinical Endocrinology and Metabolism, Endocrine, Methods, Progress in Molecular Biology and Translational Science and Contemporary Endocrinology). Conn serve

Reviews

PRAISE FOR THE SERIES "Full of interest not only for the molecular biologist-for whom the numerous references will be invaluable-but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell."-British Medical Journal