Progress in Heterocyclic Chemistry

Progress in Heterocyclic Chemistry

1st Edition - October 2, 2012

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  • Editors: Gordon Gribble, John Joule
  • eBook ISBN: 9780080968087

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Description

"Progress in Heterocyclic Chemistry" (PHC) an ongoing reference work on heterocyclic chemistry is published with the active involvement of The International Society of Heterocyclic Chemistry (ISHC) whose aim is to promote heterocyclic chemistry, in particular by serving as the primary sponsoring agency for the ISHC-Congress, a large biannual meeting attracting up to a thousand participants.

Key Features

  • Recognized as the premiere review of heterocyclic chemistry
  • Contributions from leading researchers in the field
  • Systematic survey of the important 2011 heterocyclic chemistry literature

Readership

Academic and industrial chemists and advanced students interested in heterocyclic chemistry

Table of Contents

  • Series Page

    Foreword

    Editorial Advisory Board Members Progress in Heterocyclic Chemistry

    Chapter 1 Heterocycles and Medicine

    1.1 Introduction

    1.2 Furan and Benzofuran

    1.3 Thiophene

    1.4 Pyrrole

    1.5 Thiazole

    1.6 Imidazole and Fused Imidazole

    1.7 Triazole

    1.8 Pyrazole

    1.9 Oxadizole and Thiadiazole

    1.10 Pyridine

    1.11 Pyrimidine and Pyrimidinone

    1.12 Pyrazine

    1.13 Piperazine

    1.14 Morpholine

    1.15 Indole

    1.16 Indazole

    1.17 Oxindole

    1.18 Quinoline and Dihydroquinoline

    1.19 Benzoazepines and Oxepine

    1.20 Pyrrolopyrimidine and Pyrrolopyridine

    1.21 Benzoisoxazoles and Benzoisothiazole

    1.22 Quinazoline

    1.23 Quinoxaline

    1.24 Pteridine

    1.25 Conclusion

    Chapter 2 Progress in Quinoxaline Synthesis (Part 1)

    2.1 Introduction

    2.2 Condensation of 1,2-Diaminobenzenes (1,2-DABs; ortho-Phenylenediamines) and Derivatives with Various Two-Carbon Unit Suppliers

    2.3 Condensation of o-Benzoquinone Diimines and Diimides with Various Two-Carbon Unit Suppliers

    Chapter 3 Three-Membered Ring Systems

    3.1 Introduction

    3.2 Epoxides

    3.3 Aziridines

    Chapter 4 Four-Membered Ring Systems

    4.1 Introduction

    4.2 Azetidines, Azetines, and Related Systems

    4.3 Monocyclic 2-Azetidinones (β-Lactams)

    4.4 Fused and Spirocyclic β-Lactams

    4.5 Oxetanes, Dioxetanes, and 2-Oxetanones (β-Lactones)

    4.6 Thietanes and Related Systems

    4.7 Silicon and Phosphorus Heterocycles. Miscellaneous

    Chapter 5.1 Five-Membered Ring Systems

    5.1.1 Introduction

    5.1.2 Reviews, Accounts, and Books on Thiophene, Selenophene, and Tellurophene Chemistry

    5.1.3 Synthesis of Thiophenes

    5.1.4 Elaboration of Thiophenes and Benzothiophenes

    5.1.5 Synthesis of Thiophenes, Se/Te for Use in Material Science

    5.1.6 Thiophene, Se/Te Derivatives in Medicinal Chemistry

    5.1.7 Selenophenes and Tellurophenes

    Chapter 5.2 Five-Membered Ring Systems

    5.2.1 Introduction

    5.2.2 Synthesis of Pyrroles

    5.2.3 Reactions of Pyrroles

    5.2.4 Synthesis of Indoles

    5.2.5 Reactions of Indoles

    5.2.6 Isatins, Oxindoles, Indoxyls, and Spirooxindoles

    5.2.7 Carbazoles

    5.2.8 Carboline Analogs and Azaindoles

    5.2.9 Isoindoles

    Chapter 5.3 Five-Membered Ring Systems: Furans and Benzofurans

    5.3.1 Introduction

    5.3.2 Reactions

    5.3.3 Synthesis

    Chapter 5.4 Five-Membered Ring Systems: With More than One N Atom

    5.4.1 Introduction

    5.4.2 Pyrazoles and Ring-Fused Derivatives

    5.4.3 Imidazoles and Ring-Fused Derivatives

    5.4.4 1,2,3-Triazoles and Ring-Fused Derivatives

    5.4.5 1,2,4-Triazoles and Ring-Fused Derivatives

    5.4.6 Tetrazoles and Ring-Fused Derivatives

    Chapter 5.5 Five-Membered Ring Systems: With N and S (Se) Atoms

    5.5.1 Introduction

    5.5.2 Thiazoles

    5.5.3 Isothiazoles

    5.5.4 Thiadiazoles

    5.5.5 Selenazoles

    Chapter 5.6 Five-Membered Ring Systems: With O and S (Se, Te) Atoms

    5.6.1 1,3-Dioxoles and Dioxolanes

    5.6.2 1,3-Dithioles and Dithiolanes

    5.6.3 1,3-Oxathioles and Oxathiolanes

    5.6.4 1,2-Dioxolanes

    5.6.5 1,2-Dithioles and Dithiolanes

    5.6.6 1,2-Oxathioles and Oxathiolanes

    5.6.7 Three Heteroatoms

    Chapter 5.7 Five-Membered Ring Systems with O and N Atoms

    5.7.1 Isoxazoles

    5.7.2 Isoxazolines

    5.7.3 Isoxazolidines

    5.7.4 Oxazoles

    5.7.5 Oxazolines

    5.7.6 Oxazolidines

    5.7.7 Oxadiazoles

    Chapter 6.1 Six-Membered Ring Systems: Pyridine and Benzo Derivatives

    6.1.1 Introduction

    6.1.2 Pyridines

    6.1.3 Synthesis of Pyridine N-Oxides

    6.1.4 Reactions of Pyridine N-Oxides

    6.1.5 Isoquinolines and Quinolines

    Chapter 6.2 Six-Membered Ring Systems

    6.2.1 Introduction

    6.2.2 Pyridazines and Benzo Derivatives

    6.2.3 Pyrimidines and Benzo Derivatives

    6.2.4 Pyrazines and Benzo Derivatives

    Chapter 6.3 Triazines, Tetrazines, and Fused Ring Polyaza Systems

    6.3.1 Triazines

    6.3.2 Tetrazines

    6.3.3 Fused [6] + [5] Polyaza Systems

    Chapter 6.4 Six-Membered Ring Systems: With O and/or S Atoms

    6.4.1 Introduction

    6.4.2 Heterocycles Containing One Oxygen Atom

    6.4.3 Heterocycles Containing One Sulfur Atom

    6.4.4 Heterocycles Containing Two or More Oxygen Atoms

    6.4.5 Heterocycles Containing Both Oxygen and Sulfur in the Same Ring

    Chapter 7 Seven-Membered Rings

    7.1 Introduction

    7.2 Seven-Membered Systems Containing One Heteroatom

    7.3 Seven-Membered Systems Containing Two Heteroatoms

    7.4 Seven-Membered Systems Containing Three or More Heteroatoms

    7.5 Future Directions

    Chapter 8 Eight-Membered and Larger Rings

    8.1 Introduction

    8.2 Carbon–Oxygen Rings

    8.3 Carbon–Nitrogen Rings

    8.4 Carbon–Sulfur Rings

    8.5 Carbon–Phosphorus Rings

    8.6 Carbon–Selenium Rings

    8.7 Carbon–Nitrogen–Oxygen Rings

    8.8 Carbon–Nitrogen–Sulfur Rings

    8.9 Carbon–Oxygen–Sulfur Rings

    8.10 Carbon–Oxygen/Nitrogen–Phosphorus Rings

    8.11 Carbon–Sulfur–Arsenic Rings

    8.12 Carbon–Nitrogen–Oxygen–Sulfur Rings

    8.13 Carbon–Nitrogen–Oxygen–Phosphorus Rings

    Index

Product details

  • No. of pages: 540
  • Language: English
  • Copyright: © Elsevier 2012
  • Published: October 2, 2012
  • Imprint: Elsevier
  • eBook ISBN: 9780080968087

About the Editors

Gordon Gribble

Gordon Gribble is Emeritus Professor and Research Professor of Chemistry at Dartmouth College, Hanover, USA, where he has been since 1968. His research interests cover several areas of organic chemistry, most of which involve synthesis, including novel indole chemistry, triterpenoid synthesis, and new synthetic methodology. Prof Gribble also has a deep interest in naturally occurring organohalogen compounds, and in the chemistry of wine and wine making.

Affiliations and Expertise

Dartmouth Professor, Chemistry, Dartmouth College, Hanover, USA

John Joule

John Arthur Joule did his BSc, MSc, and PhD degrees at The University of Manchester, obtaining his PhD in 1961. He then undertook post-doctoral work at Princeton University and Stanford University, before joining the academic staff of the Chemistry Department at The University of Manchester in 1963, where he is currently a Professor. In 1996 he received an RSC Medal for Heterocyclic Chemistry.

Affiliations and Expertise

Emeritus Professor, The University of Manchester, UK

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