Progress in Chemical Toxicology - 1st Edition - ISBN: 9780125365048, 9781483219233

Progress in Chemical Toxicology

1st Edition

Volume 4

Editors: Abraham Stolman
eBook ISBN: 9781483219233
Imprint: Academic Press
Published Date: 1st January 1967
Page Count: 440
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Progress in Chemical Toxicology, Volume 4 covers the capabilities of paper and thin-layer chromatography to separate closely resembling drugs and some of their metabolites. The book discusses the use of interfering compounds and artifacts in the identification of drugs in autopsy material; paper and thin layer chromatographic techniques for separation and identification of barbiturates and related hypnotics; and the forensic chemical detection of digitalis glycosides. The text also describes the applications of atomic absorption spectrometry to trace metal analyses of toxicological materials; and the toxicology of insecticides, rodenticides, herbicides, and phytopharmaceutical compounds. The combined action of drugs with toxicological implications is also considered. Chemists, toxicologists, biochemists, and forensics will find the book invaluable.

Table of Contents

Contents Contributors Preface Contents of Other Volumes Interfering Compounds and Artifacts in the Identification of Drugs in Autopsy Material I. Introduction II. Origin and Occurrence of Interfering Compounds III. Interfering Compounds (a) Extractable by Organic Solvents from Aqueous Acid Solution IV. Interfering Substances (c) Extractable by Organic Solvents from Aqueous Solution at pH 9 V. Interfering Compounds (b) Extractable by Organic Solvents from Aqueous, Strongly Alkaline Solution VI. Incidence of Interfering Endogenous Compounds References Paper and Thin Layer Chromatographic Techniques for Separation and Identification of Barbiturates and Related Hypnotics I. Introduction II. Facing the Problem III. Isolation and Preliminary Tests IV. Paper Chromatography V. Thin Layer Chromatography References Forensic Chemical Detection of Digitalis Glycosides I. Introduction II. Isolation and Identification Techniques for Digitalis Glycosides III. Detection and Determination of Digitalis Glycosides References Applications of Atomic Absorption Spectrometry to Trace Metal Analyses of Toxicological Materials I. Introduction II. Instrumentation for Atomic Absorption III. General Atomic Absorption Procedures IV. Specific Applications to Toxicological Analyses References Toxicology of Insecticides, Rodenticides, Herbicides, and Phytopharmaceutical Compounds I. Introduction II. Insecticides and Insect Repellents III. Rodenticides IV. Herbicides V. Phytopharmaceutical Compounds References Combined Action of Drugs with Toxicological Implications—Part II I. Introduction II. Increased Duration of Combined Drug Action References Author Index Subject Index


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© Academic Press 1969
Academic Press
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About the Editor

Abraham Stolman

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