Programmed Cell Death Part B, Volume 446

1st Edition

Editors: Roya Khosravi-Far Zahra Zakeri Richard Lockshin Mauro Piacentini
Hardcover ISBN: 9780123744647
eBook ISBN: 9780080888132
Imprint: Academic Press
Published Date: 29th July 2008
Page Count: 504
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Description

One of the major goals of researchers in the field of apoptosis is to identify targets for novel therapies in cancer, AIDS, and Alzheimer’s disease. Understanding the molecular mechanisms of the various components of the apoptotic pathways is the first step to reaching this goal.

The 2002 Nobel Prize in Physiology or Medicine was awarded to Sydney Brenner (United Kingdom), H. Robert Horvitz (US) and John E. Sulston (UK) "for their discoveries concerning genetic regulation of organ development and programmed cell death." Cell death is a fundamental aspect of embryonic development, normal cellular turnover and maintenance of homeostasis (maintaining a stable, constant environment) on the one hand, and aging and disease on the other. This volume addresses the significant advances with the techniques that are being used to analyze cell death.

Key Features

  • This volume provides the necessary, trusted methods to carry out this research on these latest therapeutic techniques. Once researchers understand the molecular mechanisms of the apoptotic pathways, they can begin to develop new therapies.

  • Presents key methods on studying tumors and how these cancer cells evade cell death.

  • Eliminates searching through many different sources to avoid pitfalls so the same mistakes are not made over and over.

Readership

Biochemists, molecular biologists, cell biologists, physiologists, and developmental biologists.


Details

No. of pages:
504
Language:
English
Copyright:
© Academic Press 2008
Published:
Imprint:
Academic Press
eBook ISBN:
9780080888132
Hardcover ISBN:
9780123744647

About the Editors

Roya Khosravi-Far Editor

Affiliations and Expertise

Harvard Medical School, Boston, MA, USA

Zahra Zakeri Editor

Affiliations and Expertise

Queens College of City University of New York, Flushing, USA

Richard Lockshin Editor

Affiliations and Expertise

St John's University, Jamaica, NY, USA

Mauro Piacentini Editor

Affiliations and Expertise

University of Rome, Italy