Volumes in this widely revered series present comprehensive reviews of drug substances and additional materials, with critical review chapters that summarize information related to the characterization of drug substances and excipients. This organizational structure meets the needs of the pharmaceutical community and allows for the development of a timely vehicle for publishing review materials on this topic.

The scope of the Profiles series encompasses review articles and database compilations that fall within one of the following six broad categories: Physical profiles of drug substances and excipients; Analytical profiles of drug substances and excipients; Drug metabolism and pharmacokinetic profiles of drug substances and excipients; Methodology related to the characterization of drug substances and excipients; Methods of chemical synthesis; and Reviews of the uses and applications for individual drug substances, classes of drug substances, or excipients.

Key Features

  • Contributions from leading authorities
  • Informs and updates on all the latest developments in the field


Medicinal, pharmaceutical, and analytical chemists; pharmacologists

Table of Contents

  1. Alendronate Sodium
  2. Gennady Ananchenko, Jasmina Novakovic, and Anna Tikhomirova

  3. Aripiprazole
  4. Febry Ardiana, Maria L.A.D. Lestari, and Gunawan Indrayanto

  5. Butyl Methoxy Dibenzoylmethane
  6. Jutta Kockler, Sherryl Robertson, Michael Oelgemöller, Murray Davies, Bruce Bowden, Harry G. Brittain, and Beverley D. Glass

  7. Carvedilol
  8. Kevin Beattie, Geeta Phadke, and Jasmina Novakovic

  9. Melatonin
  10. Fatmah A.M. Al-Omary

  11. Menadione
  12. Ghada S. Hassan

  13. Analytical Profile of Moxidectin
  14. Atul Awasthi, Majid Razzak, Raida Al-Kassas, Joanne Harvey, and Sanjay Garg

  15. Paroxetine Hydrochloride
  16. David Germann, George Ma, Feixue Han, and Anna Tikhomirova

  17. Paroxetine Hydrochloride: Polymorphs and Solvatomorphs
  18. Harry G. Brittain

  19. Sucralose
  20. Omar A.A. AlDeeb, Hoda Mahgoub, and Nagwa H. Foda

  21. Tramadol Hydrochloride

    Robert Smyj, Xiao-Ping Wang, and Feixue Han


No. of pages:
© 2013
Academic Press
Electronic ISBN:
Print ISBN:

About the editor

Harry Brittain

Center for Pharmaceutical Physics, Milford, NJ, USA