Description

Principles of Bacterial Pathogenesis presents a molecular perspective on a select group of bacterial pathogens by having the leaders of the field present their perspective in a clear and authoritative manner. Each chapter contains a comprehensive review devoted to a single pathogen. Several chapters include work from authors outside the pathogenesis field, providing general perspectives on the evolution, regulation, and secretion of virulence and determinants.

Key Features

Key Features * Explains the basic principles of bacterial pathogenesis * Covers diverse aspects integrating regulation, cellular microbiology and evolution of microbial disease of humans * Discusses current strategies for the identification of virulence determinants and the methods used by microbes to deliver virulence factors * Presents authoritative treatises of the major disease microorganisms

Readership

Graduates and researchers in microbiology, molecular biology, cell biology, immunology, and infectious diseases.

Table of Contents

Contributors. E.A. Groisman, Preface. H. Ochman, Evolution of Bacterial Pathogenesis. J.R. Harper and T.J. Silhavy, Germ Warfare: The Mechanisms of Virulence Factor Delivery. C. J. Dorman and S.G.J. Smith, Regulation of Virulence Gene Expression in Bacterial Pathogens. A. Camilli, D.S. Merrell, and J.J. Mekalanos, Strategies to Identify Bacterial Pathogenicity Factors. J.R. Alfano and A. Collmer, Mechanisms of Bacterial Pathogenesis in Plants: Familiar Foes in a Foreign Kingdom. A.P. Boyd & G.R. Cornelis, Yersinia. C.A. Scherer and S.I. Miller, Molecular Pathogenesis of Salmonellae. P.J. Sansonetti, C. Egile, and C. Wennerås, Shigellosis: From Disease Symptoms to Molecular and Cellular Pathogenesis. J.L. Puente and B.B. Finlay, Pathogenic Escherichia coli. V.J. DiRita, Molecular Basis of Vibrio cholerae Pathogenesis. T.L. Cover, D.E. Berg, M.J. Blaser, and H.L.T. Mobley, H. Pylori, Pathogenesis. S.D. Gray-Owen, C. Dehio, T. Rudel, M. Naumann, and T.F. Meyer, Neisseria. P.A. Cotter and J.F. Miller, Bordetella. C.M. Tang, D.W. Hood, and E.R. Moxon, Pathogenesis of Haemophilus Influenzae Infections. M. Caparon, Pathogenic Mechanisms in Streptococcal Diseases. H. Fsihi, P. Steffen, and P. Cosart, Listeria Monocytogenes. Index.

Details

No. of pages:
826
Language:
English
Copyright:
© 2001
Published:
Imprint:
Academic Press
Print ISBN:
9780123042200
Electronic ISBN:
9780080539584

About the author

Eduardo Groisman

Dr. Eduardo A. Groisman is a Professor of Molecular Microbiology at the Washington University School of Medicine and an Associate Investigator of the Howard Hughes Medical Institute. He is an accomplished microbiologist with an interest in bacterial pathogenesis investigating the regulation and function of virulence determinants and the evolution of bacterial pathogens.