Post-Genomic Cardiology

Post-Genomic Cardiology

1st Edition - February 26, 2007

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  • Editor: José Marín-García
  • eBook ISBN: 9780080554549

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Description

Recent advances in molecular and cellular biology have markedly changed our understanding of the heart, and this is having tremendous ramifications for the clinician. This unique reference offers a comprehensive and critical evaluation of this contribution in the field of cardiovascular molecular medicine providing the reader with a sense of new directions in which molecular medicine might be applied. It begins with a detailed primer that makes readily accessible recent molecular, genetic and cellular techniques. Rounding out the coverage of this exciting field are critical and comprenhesive discussions on the use of molecular, genetic and cellular techniques used to identify the etiology and pathophysiology of specific cardiac diseases.

Key Features

* Discusses diagnostic and therapeutic options available not only in the adult and aging individuals but also in infants/children
* Numerous illustrations and flow-charts
* Explans cutting-edge molecular techniques, including analysis of mitochondria, their role in cardiac dysfunction and updated analysis of Cardioprotection and Metabolic Syndrome
* Presentation of recent translational studies for the treatment of cardiovascular diseases is included (e.g., gene therapy, pharmacological treatments and stem cell transplantation)

Readership

Cardiologists, Internists, Pathophysiologists, Pediatricians, Gerontologists, Basic Researchers, Medical and Graduate Students

Table of Contents

  • BIOCHEMICAL, CELLULAR AND MOLECULAR FUNCTIONING OF THE HEART
    Introduction to Post-Genomic Cardiology
    Molecular and Biochemical Methodology in the Post-Genomic Era
    Cardiovascular Gene Expression
    Cellular Techniques
    Cardiovascular Signaling Pathways
    PEDIATRIC CARDIOLOGY IN THE POST-GENOMIC ERA
    Cardiac Development: Molecular and Genetic Analysis
    Congenital and Adquired Heart Disease
    POST-GENOMIC ANALYSIS OF CORONARY ARTERY DISEASE, ANGIOGENESIS AND HYPERTENSION
    Molecular Basis of Lipoproteins Disorders, Atherogenesis and Thrombosis
    Ischemia and Myocardial Infarction: A Post-Genomic Appraisal
    Cellular Pathways and Molecular Events in Cardioprotection
    Cardiac Neovascularization: Angiogenesis, Arteriogenesis and Vasculogenesis
    Systemic and Pulmonary Hypertension
    POSTGENOMIC ANALYSIS OF THE MYOCARDIUM
    Cardiomyopathies
    Heart Response to Inflammation and Infection
    THE FAILING HEART
    Molecular analysis of heart failure and remodeling
    MOLECULAR AND GENETIC ANALYSIS OF METABOLIC DISORDERS
    Fatty Acid and Glucose Metabolism in Cardiac Disease
    MOLECULAR GENETIC OF DYSRHYTHMIAS
    Dysrhythmias and Sudden Death
    GENES, GENDER AND ENVIRONMENT
    Gender and Cardiovascular Disease
    AGING AND THE CARDIOVASCULAR SYSTEM
    The Aging Heart: A Post-Genomic Appraisal
    LOOKING TO THE FUTURE
    Future of Post-Genomic Cardiology
    GLOSSARY
    INDEX

Product details

  • No. of pages: 688
  • Language: English
  • Copyright: © Academic Press 2007
  • Published: February 26, 2007
  • Imprint: Academic Press
  • eBook ISBN: 9780080554549

About the Editor

José Marín-García

Dr.José Marín-García, highly respected cardiologist, is the current Director of Molecular Cardiology and Neuromuscular Institute in Highland Park, NJ. He has 189 listed publications and an H-index of 30. He has written and edited Mitochondria and the heart (2005), Aging and the Heart (2008), Signaling in the Heart (2008). Heart Failure (2010), Post-Genomic Cardiology (2007), and Mitochondria and Their Role in Cardiovascular Disease (2012).

Affiliations and Expertise

Director, The Molecular Cardiology and Neuromuscular Institute, Highland Park, NJ, USA

About the Author

José Marín-García

Dr.José Marín-García, highly respected cardiologist, is the current Director of Molecular Cardiology and Neuromuscular Institute in Highland Park, NJ. He has 189 listed publications and an H-index of 30. He has written and edited Mitochondria and the heart (2005), Aging and the Heart (2008), Signaling in the Heart (2008). Heart Failure (2010), Post-Genomic Cardiology (2007), and Mitochondria and Their Role in Cardiovascular Disease (2012).

Affiliations and Expertise

Director, The Molecular Cardiology and Neuromuscular Institute, Highland Park, NJ, USA

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