Polyphenols: Prevention and Treatment of Human Disease

Polyphenols in Prevention and Treatment of Human Disease, Second Edition, authoritatively covers the evidence of the powerful health benefits of polyphenols, ranging from protection against cardiovascular disease, cancer, obesity, diabetes, and osteoporosis. This collection represents an international group of experts in polyphenol research and the coverage is appropriately broad, drawing in endocrinology, public health, cardiology, pharmacology, agriculture, and veterinary science. Researchers from diverse backgrounds will gain insight into how clinical observations and practices can feed back into the research cycle and will, therefore, be able to develop more targeted insights into the mechanisms of disease. For decades, conventional therapies have proven unsuccessful or have many side effects in the prevention of disease. This reference fills a void in the research field which nutritionists and alternative therapies may be applicable. Advancing research in the understanding and treatment of disease will be widely accepted.

• Provides diseases in one volume and expands coverage to neurology
• Describes polyphenol modulation of blood flow and oxygenation, being a potential mechanism of protection to prevent vascular atherosclerosis
• Describes how polyphenols and antioxidants frequently change immune defenses and actions
• Focuses on most important areas of research and provides insights into their relationships and translational opportunities

Biochemists, endocrinologists, nutritionists, dieticians, and clinical researchers interested in how the mechanisms of polyphenols contribute to the prevention and treatment of disease

1. Vascular Protective Effects of Fruit Polyphenols
2. Atherosclerosis and Mediterranean Diet Polyphenols
3. Polyphenol Modulation of Blood Flow and Oxygenation
4. Flax Lignan in the Prevention of Atherosclerotic Cardiovascular Diseases
5. Anthocyanins in Vascular Diseases

CARDIAC HEALTH AND POLYPHENOLS
6. Pharmacology of Polyphenols in Cardiac Remodeling
7. Cacao Polyphenols Influence the Regulation of Apolipoproteins
8. Polyphenol Consumption and Blood Pressure
9. Cardiovascular Effects of Hesperidin
10. Wine Polyphenols in the Management of Cardiovascular Risk Factors
11. Cocoa, Flavonoids and Cardiovascular Protection
12. Emerging Applications of Metabolomics to Polyphenols and CVD Biomarker Discovery
13. Role of Gallic Acid in Cardiovascular Disorders
14. Cranberry Polyphenols: Effects on Cardiovascular Risk Factors
15. Polyphenols and Cardiometabolic Syndrome
16. Cocoa Polyphenols and Cardiovascular Health
17. The Use of Bergamot-Derived Polyphenol Fraction in Cardiometabolic Risk Prevention and its Possible Mechanisms of Action
18. Fruit Polyphenols and Postprandial Inflammatory Stress

CANCER PREVENTION AND TREATMENT OF POLYPHENOLS
19. Modulation of Drug-Metabolizing Enzymes and Transporters by Polyphenols as an Anticarcinogenic Effect
20. Cancer Chemoprevention by Dietary Polyphenols: Role for Epigenetics and Inflammation
21. Polyphenol-Mediated In Vivo Cellular Responses during Carcinogenesis
22. Preventive Effects of Plant Polyphenols in the Promotion of Mammary Cancer and Testicular Damage Induced by Alcohol Drinking
23. Antioxidant and Pro-Oxidant Activities of Green Tea Polyphenols in Cancer Prevention
24. Polyphenols in Prostate Cancer
25. Modifying Effects of Polyphenols on Acute Colitis and Inflammation-Associated Colon Carcinogenesis
26. Bioavailability of Soy-Derived Isoflavones and Human Breast Cancer
27. Biologi