Physiological and Biotechnological Aspects of Extremophiles

Physiological and Biotechnological Aspects of Extremophiles

1st Edition - June 4, 2020

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  • Editors: Richa Salwan, Vivek Sharma
  • Paperback ISBN: 9780128183229
  • eBook ISBN: 9780128183236

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Physiological and Biotechnological Aspects of Extremophiles highlights the current and topical areas of research in this rapidly growing field. Expert authors from around the world provide the latest insights into the mechanisms of these fascinating organisms use to survive.The vast majority of extremophiles are microbes which include archaea, bacteria and some eukaryotes. These microbes live under chemical and physical extremes that are usually lethal to cellular molecules, yet they manage to survive and even thrive. Extremophiles have important practical uses. They are a valuable source of industrially important enzymes and recent research has revealed novel mechanisms and biomolecular structures with a broad range of potential applications in biotechnology, biomining, and bioremediation.Aimed at research scientists, students, microbiologists, and biotechnologists, this book is an essential reading for scientists working with extremophiles and a recommended reference text for anyone interested in the microbiology, bioprospecting, biomining, biofuels, and extremozymes of these organisms.

Key Features

  • Shows the implications of the physiological adaptations of microbes from extreme habitats that are largely contributed by their biomolecules from basic to applied research
  • Provides in-depth knowledge of genomic plasticity and proteome of different extremophiles
  • Gives detailed and comprehensive insight about use of genetic engineering as well as genome editing for industrial applications


Research scientists, students, microbiologists and biotechnologists. This book is essential reading for scientists working with extremophiles and a recommended reference text for anyone interested in the microbiology of these organisms, as well as bioprospecting, biomining, biofuels and extremozymes

Table of Contents

  • Preface & Intro & Acknowledgements
    Richa Salwan
    Physiological aspects
    1. Overview of extremophiles
    Richa Salwan and Vivek Sharma
    2. Physiology of Extremophiles
    Richa Salwan and Vivek Sharma
    3. Mechanism of resistance focusing on copper, mercury and arsenic in extremophilic organisms, how acidophiles and thermophiles cope with these metals
    Javiera Alejrandra Norambuena
    4. Halotolerant microbes and their applications in sustainable agriculture
    Suprasanna Penna, Jayant Kulkarni, Sandeep Sharma and Ashish Kumar Srivastava
    5. Halophilic microorganisms: interesting group of extremophiles with important applications in biotechnology and environment
    Lobna Daoud and Mamdouh Ben Ali
    6. Overview of extremophiles and their food and medical applications
    Jane Ann Irwin
    7. Applications of extremophiles in Astrobiology
    Rebecca S. Thombre, Parag A. Vaishampayan and Felipe Gomez
    8. High-pressureAdaptation ofExtremophiles and Biotechnological Applications
    Philippe Oger, Judith Peters and Marta Salvador-Castell
    9. Fructanogenic Halophiles: A new Perspective on Extremophiles
    Ebru Toksoy Oner, Gülbahar Abaramak and Onur Kirtel
    10. Applications of sulfur-oxidizing bacteria
    Kavita Rana, Neerja Rana and Birbal Singh
    11. Physiological and genomic perspective of extremophiles in high salt concentrations
    Preeti Mehta, Ashish Verma and Sachin Kumar Biotechnological aspects
    12. Genome editing in extremophiles using CRISPR/Cas9 technology
    Vivek Sharma and Richa Salwan
    13. Lipases/esterases from extremophiles: main features and potential biotechnological applications
    Luigi Mandrich and Valentina De Luca
    14. Thermostable ThermoanaerobacterAlcohol Dehydrogenases And Their Use In Organic Synthesis
    Sean Michael Scully and Johann Orlygsson Sr.
    15. Biotechnological platforms of the moderate thermophiles, Geobacillus species: notable properties and genetic tools
    Hirokazu Suzuki and Keisuke Wada
    16. Thermophiles and Thermophilic Hydrolases
    Shilpi Ghosh and Khusboo Lepcha
    17. Effects of single nucleotide mutations in the genomes of multi-drug resistant 19biofilm producing Pseudomonas aeruginosa
    Babu Ramanathan, Sanjay Gunabalan and Chew Jactty
    18. Understanding the structural basis of adaptation in enzymes from psychrophiles
    Mahejibin Khan
    19. Molecular and functional characterization of major compatible solute in Deep Sea halophilic actinobacteria of active volcanic Barren Island, Andaman and Nicobar Islands, India
    Balakrishnan Meena, Lawrance Anburajan and Ramalingam Kirubagaran
    20. Antarctic microorganisms as a source of biotechnological products
    Fernanda Abreu and Tarcisio Correa
    21. The Secretomes of Extremophiles
    Mazen Saleh and Eyad Kinkar
    22. Carbonic anhydrase from extremophiles and their potential use in biotechnological applications
    Clemente Capasso and Claudiu Supuran
    23. Understanding the Protein Sequence and Structural Adaptation in Extremophilic Organisms through Machine Learning Techniques
    Abhigyan Nath
    24. Exploration of extremophiles genomes through metagenomics for hidden Biotechnological and future potential
    Pijush Basak, Arpita Biswas and Maitree Bhattacharyya
    25. The Ecophysiology, Genetics, Adaptive Significance, and Biotechnology of Nickel Hyperaccumulation in Plants
    Anthony Logan Ferrero, Peter R. Walsh and Nishanta Rajakaruna

Product details

  • No. of pages: 386
  • Language: English
  • Copyright: © Academic Press 2020
  • Published: June 4, 2020
  • Imprint: Academic Press
  • Paperback ISBN: 9780128183229
  • eBook ISBN: 9780128183236

About the Editors

Richa Salwan

Dr. Salwan is presently working as Young Scientist under DST funded project at Chandigarh University as Principal Scientist. She has published more than twenty research papers in journals of international reputations. She has also published 6 book chapters and presented her research in international conferences. She has been awarded National post doc fellowship (Npdf- SERB) in 2015 and 2017. She has completed her PhD in Biological Sciences from AcSIR – Academy of Scientific & Innovative Research, New Delhi India. She is working on the exploration of extremophiles for industrial relevant enzymes and agricultural benefits.

Affiliations and Expertise

DST Young Scientist, University Centre For Research and Development, Chandigarh University, Punjab, India

Vivek Sharma

Dr. Sharma’s work focuses on molecular aspects of plant beneficial microbes. He has published several research papers in journals including International Journal of Biological macromolecules, Frontiers in Microbiology, European Journal of Plant Pathology, Current Microbiology, Pesticide Biochemistry and Physiology. He is a reviewer in journals of international reputation such as MDPI Pathogens, Molecular Biotechnology, Folia Microbiology, Physiological and Molecular Plant Pathology, Archive of Microbiology etc. Dr. Vivek Sharma did his PhD from CSIR-Institute of Himalyan Bioresource Technology, Palampur Himachal Pradesh, India. Dr. Sharma has qualified CSIR-UGC junior Research Fellowship and awarded DST Young Scientist award under Fast Track Scheme. Dr. Sharma was selected for ARO post doc fellowship at Israel in 2017-18. He is presently working as Assistant Professor in University Centre For Research and Development at Chandigarh University, Punjab. He is having research experience of more than 12 years in exploring molecular attributes of Trichoderma involved in different plant benefits.

Affiliations and Expertise

Professor, University Centre For Research and Development, Chandigarh University Punjab, India

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