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Physiological and Biotechnological Aspects of Extremophiles - 1st Edition - ISBN: 9780128183229, 9780128183236

Physiological and Biotechnological Aspects of Extremophiles

1st Edition

Editors: Richa Salwan Vivek Sharma
Paperback ISBN: 9780128183229
eBook ISBN: 9780128183236
Imprint: Academic Press
Published Date: 5th June 2020
Page Count: 386
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Physiological and Biotechnological Aspects of Extremophiles highlights the current and topical areas of research in this rapidly growing field. Expert authors from around the world provide the latest insights into the mechanisms of these fascinating organisms use to survive.

The vast majority of extremophiles are microbes which include archaea, bacteria and some eukaryotes. These microbes live under chemical and physical extremes that are usually lethal to cellular molecules, yet they manage to survive and even thrive. Extremophiles have important practical uses. They are a valuable source of industrially important enzymes and recent research has revealed novel mechanisms and biomolecular structures with a broad range of potential applications in biotechnology, biomining, and bioremediation.

Aimed at research scientists, students, microbiologists, and biotechnologists, this book is an essential reading for scientists working with extremophiles and a recommended reference text for anyone interested in the microbiology, bioprospecting, biomining, biofuels, and extremozymes of these organisms.

Key Features

  • Shows the implications of the physiological adaptations of microbes from extreme habitats that are largely contributed by their biomolecules from basic to applied research

  • Provides in-depth knowledge of genomic plasticity and proteome of different extremophiles

  • Gives detailed and comprehensive insight about use of genetic engineering as well as genome editing for industrial applications


Research scientists, students, microbiologists and biotechnologists. This book is essential reading for scientists working with extremophiles and a recommended reference text for anyone interested in the microbiology of these organisms, as well as bioprospecting, biomining, biofuels and extremozymes

Table of Contents

Preface & Intro & Acknowledgements

Richa Salwan

Physiological aspects

1. Overview of extremophiles

Richa Salwan and Vivek Sharma

2. Physiology of Extremophiles

Richa Salwan and Vivek Sharma

3. Mechanism of resistance focusing on copper, mercury and arsenic in extremophilic organisms, how acidophiles and thermophiles cope with these metals.

Javiera Alejrandra Norambuena

4. Halotolerant microbes and their applications in sustainable agriculture

Suprasanna Penna, Jayant Kulkarni, Sandeep Sharma and Ashish Kumar Srivastava

5. Halophilic microorganisms: interesting group of extremophiles with important applications in biotechnology and environment

Lobna Daoud and Mamdouh Ben Ali

6. Overview of extremophiles and their food and medical applications

Jane Ann Irwin

7. Applications of extremophiles in Astrobiology

Rebecca S. Thombre, Parag A. Vaishampayan and Felipe Gomez

8. High-pressureAdaptation ofExtremophiles and Biotechnological Applications

Philippe Oger, Judith Peters and Marta Salvador-Castell

9. Fructanogenic Halophiles: A new Perspective on Extremophiles

Ebru Toksoy Oner, Gülbahar Abaramak and Onur Kirtel

10. Applications of sulfur-oxidizing bacteria

Kavita Rana, Neerja Rana and Birbal Singh

11. Physiological and genomic perspective of extremophiles in high salt concentrations

Preeti Mehta, Ashish Verma and Sachin Kumar

Biotechnological aspects

12. Genome editing in extremophiles using CRISPR/Cas9 technology

Vivek Sharma and Richa Salwan

13. Lipases/esterases from extremophiles: main features and potential biotechnological applications

Luigi Mandrich and Valentina De Luca

14. Thermostable ThermoanaerobacterAlcohol Dehydrogenases And Their Use In Organic Synthesis

Sean Michael Scully and Johann Orlygsson Sr.

15. Biotechnological platforms of the moderate thermophiles, Geobacillus species: notable properties and genetic tools

Hirokazu Suzuki and Keisuke Wada

16. Thermophiles and Thermophilic Hydrolases

Shilpi Ghosh and Khusboo Lepcha

17. Effects of single nucleotide mutations in the genomes of multi-drug resistant 19biofilm producing Pseudomonas aeruginosa

Babu Ramanathan, Sanjay Gunabalan and Chew Jactty

18. Understanding the structural basis of adaptation in enzymes from psychrophiles

Mahejibin Khan

19. Molecular and functional characterization of major compatible solute in Deep Sea halophilic actinobacteria of active volcanic Barren Island, Andaman and Nicobar Islands, India

Balakrishnan Meena, Lawrance Anburajan and Ramalingam Kirubagaran

20. Antarctic microorganisms as a source of biotechnological products

Fernanda Abreu and Tarcisio Correa

21. The Secretomes of Extremophiles

Mazen Saleh and Eyad Kinkar

22. Carbonic anhydrase from extremophiles and their potential use in biotechnological applications

Clemente Capasso and Claudiu Supuran

23. Understanding the Protein Sequence and Structural Adaptation in Extremophilic Organisms through Machine Learning Techniques

Abhigyan Nath

24. Exploration of extremophiles genomes through metagenomics for hidden Biotechnological and future potential

Pijush Basak, Arpita Biswas and Maitree Bhattacharyya

25. The Ecophysiology, Genetics, Adaptive Significance, and Biotechnology of Nickel Hyperaccumulation in Plants

Anthony Logan Ferrero, Peter R. Walsh and Nishanta Rajakaruna


No. of pages:
© Academic Press 2020
5th June 2020
Academic Press
Paperback ISBN:
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About the Editors

Richa Salwan

Dr. Salwan is presently working as Young Scientist under DST funded project at Chandigarh University as Principal Scientist. She has published more than twenty research papers in journals of international reputations. She has also published 6 book chapters and presented her research in international conferences. She has been awarded National post doc fellowship (Npdf- SERB) in 2015 and 2017. She has completed her PhD in Biological Sciences from AcSIR – Academy of Scientific & Innovative Research, New Delhi India. She is working on the exploration of extremophiles for industrial relevant enzymes and agricultural benefits.

Affiliations and Expertise

DST Young Scientist, University Centre For Research and Development, Chandigarh University, Punjab, India

Vivek Sharma

Dr. Sharma’s work focuses on molecular aspects of plant beneficial microbes. He has published several research papers in journals including International Journal of Biological macromolecules, Frontiers in Microbiology, European Journal of Plant Pathology, Current Microbiology, Pesticide Biochemistry and Physiology. He is a reviewer in journals of international reputation such as MDPI Pathogens, Molecular Biotechnology, Folia Microbiology, Physiological and Molecular Plant Pathology, Archive of Microbiology etc. Dr. Vivek Sharma did his PhD from CSIR-Institute of Himalyan Bioresource Technology, Palampur Himachal Pradesh, India. Dr. Sharma has qualified CSIR-UGC junior Research Fellowship and awarded DST Young Scientist award under Fast Track Scheme. Dr. Sharma was selected for ARO post doc fellowship at Israel in 2017-18. He is presently working as Assistant Professor in University Centre For Research and Development at Chandigarh University, Punjab. He is having research experience of more than 12 years in exploring molecular attributes of Trichoderma involved in different plant benefits.

Affiliations and Expertise

Professor, University Centre For Research and Development, Chandigarh University Punjab, India

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