Pharmacology of 5-HT6 receptors, Part I

Pharmacology of 5-HT6 receptors, Part I

1st Edition - November 29, 2010

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  • Editor: Franco Borsini
  • eBook ISBN: 9780123849779

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The serotonin 5-HT6 receptor represents a novel pharmacological target whose impact on physiopathology of CNS functions remains undetermined. Some receptor antagonists have been synthesized and they show a modulatory role in learning and memory processes and food intake. The pharmacology of 5-HT6 receptor agonists is still under evaluation. However, both 5-HT6 antagonists and agonists seem to exert potential antidepressant activity. Recently, a second messenger system has been discovered. 5-HT6 receptor function is becoming more and more intriguing. Thus, the aim of the present book is to try to clarify the pharmacology of 5-HT6 receptors.

Key Features

  • Written by expert researchers
  • Covers all published literature to date in the field of 5-HT6 receptors


Neuroscientists, neurologists, psychologists, psychiatrists, pharmacologists

Table of Contents

    1. 5-HT6 Medicinal Chemistry
    2. Kevin G. Liu and Albert J. Robichaud

    3. Patents
    4. Nicolas Vincent Ruiz and Gloria Oranias

    5. 5-HT6 Receptor Charactertization
    6. Teresa Riccioni

    7. 5-HT6 receptor signal transduction. Second Messenger Systems
    8. Xavier Codony, Javier Burgueño, Maria Javier Ramírez, José Miguel Vela

    9. Electrophysiology of 5-HT6 Receptors
    10. Annalisa Tassone, Graziella Madeo, Giuseppe Sciamanna, Antonio Pisani, and Paola Bonsi

    11. Genetic Variations and Association
    12. Massimo Gennarelli and Annamaria Cattaneo

    13. Pharmacokinetics of 5-HT6 Receptors Ligands

    Angelo Mancinelli

Product details

  • No. of pages: 224
  • Language: English
  • Copyright: © Academic Press 2010
  • Published: November 29, 2010
  • Imprint: Academic Press
  • eBook ISBN: 9780123849779

About the Serial Volume Editor

Franco Borsini

Franco Borsini, Head, Central & Peripheral Nervous System and General Pharmacology Area - R&D Department, sigma-tau SpA, Pomezia (Rome), Italy

Affiliations and Expertise

Head, Central & Peripheral Nervous System and General Pharmacology Area - R&D Department, sigma-tau SpA, Pomezia (Rome), Italy

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