Description

The serotonin 5-HT6 receptor represents a novel pharmacological target whose impact on physiopathology of CNS functions remains undetermined. Some receptor antagonists have been synthesized and they show a modulatory role in learning and memory processes and food intake. The pharmacology of 5-HT6 receptor agonists is still under evaluation. However, both 5-HT6 antagonists and agonists seem to exert potential antidepressant activity. Recently, a second messenger system has been discovered. 5-HT6 receptor function is becoming more and more intriguing. Thus, the aim of the present book is to try to clarify the pharmacology of 5-HT6 receptors.

Key Features

  • Written by expert researchers
  • Covers all published literature to date in the field of 5-HT6 receptors

Readership

Neuroscientists, neurologists, psychologists, psychiatrists, pharmacologists

Table of Contents

  1. 5-HT6 Medicinal Chemistry
  2. Kevin G. Liu and Albert J. Robichaud

  3. Patents
  4. Nicolas Vincent Ruiz and Gloria Oranias

  5. 5-HT6 Receptor Charactertization
  6. Teresa Riccioni

  7. 5-HT6 receptor signal transduction. Second Messenger Systems
  8. Xavier Codony, Javier Burgueño, Maria Javier Ramírez, José Miguel Vela

  9. Electrophysiology of 5-HT6 Receptors
  10. Annalisa Tassone, Graziella Madeo, Giuseppe Sciamanna, Antonio Pisani, and Paola Bonsi

  11. Genetic Variations and Association
  12. Massimo Gennarelli and Annamaria Cattaneo

  13. Pharmacokinetics of 5-HT6 Receptors Ligands

Angelo Mancinelli

Details

No. of pages:
224
Language:
English
Copyright:
© 2010
Published:
Imprint:
Academic Press
Print ISBN:
9780123849762
Electronic ISBN:
9780123849779