Pharmacognosy

Pharmacognosy

Fundamentals, Applications and Strategies

2nd Edition - August 1, 2023

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  • Editors: Simone Badal Mccreath, Yuri Clement
  • Paperback ISBN: 9780443186578

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Description

Pharmacognosy: Fundamentals, Applications and Strategies, Second Edition represents a comprehensive compilation of the philosophical, scientific and technological aspects of contemporary pharmacognosy. The book examines the impact of the advanced techniques of pharmacognosy on improving the quality, safety and effectiveness of traditional medicines, and how pharmacokinetics and pharmacodynamics have a crucial role to play in discerning the relationships of active metabolites to bioavailability and function at the active sites, as well as the metabolism of plant constituents. Structured in seven parts, the book covers the foundational aspects of Pharmacognosy, the chemistry of plant metabolites, their effects, other sources of metabolites, crude drugs from animals, basic animal anatomy and physiology, technological applications and biotechnology, and the current trends in research. New to this edition is a chapter on plant metabolites and SARS-Cov-2, extensive updates on existing chapters and the development of a Laboratory Guide to support instructors execute practical activities on the laboratory setting.

Key Features

  • Covers the main sources of natural bioactive substances
  • Contains practice questions and laboratory exercises at the end of every chapter to test learning and retention
  • Describes how pharmacokinetics and pharmacodynamics play a crucial role in discerning the relationships of active metabolites to bioavailability and function at active sites
  • Includes a dedicated chapter on the effect of plant metabolites on SARS-CoV-2

Readership

Student of pharmacology, and pharmaceutical sciences, Professionals in natural products in pharma and cosmetics industry

Table of Contents

  • Part I - Pharmacognosy 101
    1. Background to Pharmacognosy
    2. Traditional Medicine
    3. Plant Anatomy and Physiology
    4. Plant Constituents: Carbohydrates, Oils, Resins, Balsams, and Plant Hormones
    5. Plant Crude Drugs

    Part II - Plant Metabolites: Their Chemistry
    6. Evolutionary Perspectives on the Role of Plant Secondary Metabolites
    7. Glycosides
    8. Alkaloids
    9. Tannins
    10. Terpenoids
    11. Other Plant Metabolites
    12. Vitamins

    Part III - Plant Metabolites: Their Effects
    13. Chemotherapeutics
    14. Bioactive Plant Molecules, Sources and Mechanism of Action in the Treatment of Cardiovascular Disease
    15. Plant Metabolites and More Treating Various Ailments: Natural Products Treating Diseases
    16. Psychoactive Drugs
    17. Plant metabolites and SARS-Cov-2

    Part IV Metabolites from Other Sources
    18. Marine Metabolites: Oceans of Opportunity
    19. Animal Metabolites: From Amphibians, Reptiles, Aves/Birds, and Invertebrates
    20. Fungal Metabolites

    Part V - Crude Drugs From Animals
    21. Fats
    22. Waxes

    Part VI - Basic Animal Anatomy and Physiology
    23. Form and Function of the Animal Cell
    24. Proteins
    25. Pharmacokinetics
    26. Pharmacodynamics—A Pharmacognosy Perspective
    27. Drug Metabolism

    Part VII - Technological Applications Using Biological Systems
    28. Biotechnology

    Part VIII - Current Trends in Pharmacognosy Research
    29. Natural Product Structure Elucidation by NMR Spectroscopy
    30. Metabolomics Approach in Pharmacognosy
    31. Novel Targets in Drug Discovery
    32. Nanotechnology: Building and Observing at the Nanometer Scale
    33. Ethical Aspects of Working With Local Communities and Their Biological Resources
    34. Factors to Consider in Development of Nutraceutical and Dietary Supplements
    35. The Global Regulatory Framework for Medicinal Plants
    36. The Potential Role of Bioscience Industries in Small Developing Economies

Product details

  • No. of pages: 738
  • Language: English
  • Copyright: © Academic Press 2023
  • Published: August 1, 2023
  • Imprint: Academic Press
  • Paperback ISBN: 9780443186578

About the Editors

Simone Badal Mccreath

Simone Badal Mccreath

Dr. Badal McCreath is a distinguished young scientist who holds the 2014 Elsevier Early Career Woman Scientist award in Chemical Sciences for the Latin America and Caribbean region. She has over 10 years’ experience in natural products research and holds a patent pending for the anticancer potential of natural products using cancer and normal cell lines.

Dr. Badal McCreath holds a number of national and international awards and distinctions. At the University of the West Indies (UWI), Mona, she was the 2010 Inaugural Luther Speare Scholar in addition to being the Young Scientist/Technologist awardee at the biennial 23rd Science and Technology Conference and Expo hosted by the Scientific Research Council and the Jamaica Public Service Co. She along with collaborators was also the recipient of the 2013-2014 Principal’s award for best work in anticancer research, UWI, Mona. She is a current member of various editorial boards including: The Journal of Cancer Science & Clinical Research and American International Journal of Biology. She is also an advisory board member and reviewer affiliated with Open Access Biochemistry, London.

Dr. Badal McCreath is currently a Lecturer in the Department of Basic Medical Sciences at the UWI, Mona, Jamaica. In addition to having taught Pharmacognosy for 3 years at the University of Technology, Jamaica, her current work involves pioneering the development of novel Jamaican prostate cancer (PCa) cell lines - a project that received national funding totaling approximately 100,000 USD. As PCa incidence and mortality rates are highest among men of African descent, the development of these tools representative of PCa tumors will be available to the global scientific community in order to delineate reasons for the reduced survivorship among this group. These novel cell lines can be used to screen potentially derived natural drug leads for anticancer efficacy utilizing a personalized framework.

Dr. Badal McCreath is a well published author who is currently penning her first book, “A woman’s journey to success.” She is a dynamic scientific orator who has presented at many scientific meetings and conferences. She continues to share her expertise by training and supervising students at the undergraduate and postgraduate levels while volunteering on various nonprofit organizational boards including the Society for Scientific Advancement. She is passionate about implementing a framework that can elevate the nature of biomedical research in Jamaica and the Caribbean with a specific focus on anticancer research. Such a framework that will utilize the country's own natural resources can contribute to improving Jamaica's and the Caribbean's economic standing as they obtain a global competitive edge. She is also deeply committed to improving science awareness and interest at the primary and secondary levels.

Affiliations and Expertise

Lecturer and Anticancer Researcher, Biochemistry, Department of Basic Medical Sciences, Faculty of Medical Sciences Teaching and Research Complex University of the West Indies, Mona Campus, Kingston, Jamaica

Yuri Clement

Dr. Yuri N. Clement received his B.Sc. in Chemistry and Ph.D in Pharmacology from the University of the West Indies. He was appointed Professor of Pharmacology in February 2017. Dr. Clement has supervised PhD and MPhil students and was chair of the COVID-19 Therapeutics Review Committee in March 2020. He has written several book chapters, research articles in international and local scientific journals. Dr. Clement is a member of the Caribbean Academy of Sciences since 2012, and from the Traditional Medicine in the Islands since 2006.

Affiliations and Expertise

Faculty of Medical Sciences, University of the West Indies, St. Augustine, Trinidad and Tobago

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