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Pedigree Analysis in R - 1st Edition - ISBN: 9780128244302, 9780128245606

Pedigree Analysis in R

1st Edition

Author: Magnus Dehli Vigeland
Paperback ISBN: 9780128244302
eBook ISBN: 9780128245606
Imprint: Academic Press
Published Date: 1st November 2020
Page Count: 184
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Description

Pedigree Analysis in R gives an introduction to the theory of relatedness and covers a range of applications in forensic and medical genetics. The book's material was developed through teaching courses on genetic relatedness, pedigree analysis and R, and offers insights from a decade of research activities in forensic and medical genetics. The R code in the book uses the ped suite, a unified collection of packages for pedigree analysis, developed by the author. All code examples are given in full, allowing accurate reproduction of figures and results. At the end of each chapter, a selection of exercises encourages the reader to explore further and perform their own analyses.

Key Features

  • Introduction to the theory of genetic relatedness, richly illustrated with classic and novel examples
  • In-depth case studies including kinship testing, pedigree reconstruction, linkage analysis and clinical segregation analysis
  • Easy-to-follow R code with explanations
  • Based on the ped suite packages for pedigree analysis in R
  • Suitable for R users at all levels, including complete beginners
  • Exercises after each chapter

Readership

Researchers and practitioners of forensic genetics / medical genetics. Students in graduate level forensic / medical genetic courses

Table of Contents

1. Prerequisites
2. Pedigrees and Marker Data
3. Coefficients of Relatedness
4. Realised Relatedness
5. Probabilities on Pedigrees
6. Kinship Testing
7. Inference of Pairwise Relatedness
8. Pedigree Reconstruction
9. Linkage Analysis
10. Segregation Analysis for Variant Interpretation

Details

No. of pages:
184
Language:
English
Copyright:
© Academic Press 2021
Published:
1st November 2020
Imprint:
Academic Press
Paperback ISBN:
9780128244302
eBook ISBN:
9780128245606

About the Author

Magnus Dehli Vigeland

Magnus Dehli Vigeland works in the Department of Medical Genetics at Oslo University Hospital, University of Oslo, Oslo, Norway.

Affiliations and Expertise

Department of Medical Genetics, Oslo University Hospital, University of Oslo, Oslo, Norway

Ratings and Reviews