Pediatric Rheumatology Comes of Age: Part I, An Issue of Rheumatic Disease Clinics of North America

1st Edition, Volume 47-4 - October 13, 2021
Editors: Laura E. Schanberg︎, Yukiko Kimura
Language: English
Hardback ISBN:
9 7 8 - 0 - 3 2 3 - 8 9 6 8 0 - 1
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 8 9 6 8 1 - 8

This issue of Rheumatic Disease Clinics, guest edited by Drs. Laura Schanberg and Yukiko Kimura, will focus on Pediatric Rheumatology. This issue is one of four selected each year… Read more

Pediatric Rheumatology Comes of Age: Part I, An Issue of Rheumatic Disease Clinics of North America

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This issue of Rheumatic Disease Clinics, guest edited by Drs. Laura Schanberg and Yukiko Kimura, will focus on Pediatric Rheumatology. This issue is one of four selected each year by our series Consulting Editor, Dr. Michael Weisman. Part II, also edited by Drs. Kimura and Schanberg, will publish subsequently and cover additional topics relevant for pediatric rheumatologists. Topics discussed in this issue include but are not limited to: TMJ, CNO (CRMO), Update JIA treatment, Pharmacology of biologics in kids, Juvenile Spondylitis, Juvenile fibro update, JDM update, Pediatric Sjogrens, Localized scleroderma, Systemic Sclerosis, Uveitis, COVID-19 in pediatrics, Recent advances in pediatric vasculitis, and Autoinflammatory diseases.

Cover image
Title page
Table of Contents
Copyright
Contributors
Forthcoming Issues
Foreword
Preface
CARRA: The Childhood Arthritis and Rheumatology Research Alliance
Key points
The Childhood Arthritis & Rheumatology Research Alliance: The beginning (2000–2007)
The early growth years: 2006 to 2012
Carra, Inc., and the new Carra (2015–present)
Evolution and challenges
The future of the Childhood Arthritis & Rheumatology Research Alliance
Clinics care points
Juvenile Idiopathic Arthritis Treatment Updates
Key points
Introduction
Juvenile idiopathic arthritis: Oligoarthritis and polyarthritis
Enthesitis-related arthritis and juvenile psoriatic arthritis
Systemic juvenile idiopathic arthritis
Clinics care points
Recent Updates in Juvenile Spondyloarthritis
Key points
Introduction
Classification
Clinical features
Genetic susceptibility and pathogenesis
Diagnostic imaging
Disease activity measures
Treatment
Summary
Clinics care points
Disclosure
Pathogenesis and Treatment of Refractory Disease Courses in Systemic Juvenile Idiopathic Arthritis: Refractory Arthritis, Recurrent Macrophage Activation Syndrome and Chronic Lung Disease
Key points
Introduction
The need for defining refractory disease courses in systemic juvenile idiopathic arthritis
Refractory systemic juvenile idiopathic arthritis course I: refractory arthritis
Therapeutic strategies for refractory arthritis in systemic juvenile idiopathic arthritis
Refractory systemic juvenile idiopathic arthritis course II: recurrent macrophage activation syndrome
Refractory systemic juvenile idiopathic arthritis course III: systemic juvenile idiopathic arthritis–associated lung disease
Summary and future directions
Clinics care points
The Temporomandibular Joint in Juvenile Idiopathic Arthritis
Key points
Introduction
Juvenile idiopathic arthritis-associated temporomandibular joint terminology
Repercussions of temporomandibular joint involvement in juvenile idiopathic arthritis
Clinical signs and symptoms of temporomandibular joint arthritis
Imaging of temporomandibular joint arthritis
Local and systemic treatment
Orthopedic devices and surgery
Summary
Clinics care points
Uveitis in Children and Adolescents
Key points
Overview
Common uveitis syndromes
Ocular complications
Ophthalmic work-up
Therapeutic options
Treatment withdrawal
Summary
Clinics care points
Pharmacosurveillance in Juvenile Idiopathic Arthritis
Key points
Introduction
Pharmacosurveillance
Spontaneous reporting systems
Big data
Electronic health records
Administrative claims data
Registries
Drug-specific registries
Multidrug registries
Disease-specific registries
Assessing medication safety in juvenile idiopathic arthritis
Infections
Malignancies
Future challenges
Outcome Measures in Pediatric Rheumatic Disease
Key points
Outcome measures in pediatric rheumatic disease
Outcome measures in juvenile idiopathic arthritis
Outcome measures in juvenile dermatomyositis
Outcome measures in childhood-onset lupus
Outcome measures in vasculitis
Future directions
Clinics care points
Updates on Juvenile Dermatomyositis from the Last Decade: Classification to Outcomes
Key points
Introduction
Classification
Serologic classification of juvenile dermatomyositis
Assessment
Pathogenesis
Treatment
Long-term outcomes
Summary
Clinics care points
Disclosure
Chronic Nonbacterial Osteomyelitis: Insights into Pathogenesis, Assessment, and Treatment
Key points
Overview
Epidemiology
Etiology and pathogenesis
Clinical manifestations
Laboratory studies
Diagnostic imaging
Monitoring disease activity
Bone biopsy
Diagnostic criteria
Treatment
Outcome and prognosis
Summary
Clinics care points
Unique Aspects of Pediatric Sjögren Disease
Key points
Introduction
Epidemiology
History, controversy, and terminology
Pathophysiology
Clinical features
Laboratory and diagnostic testing
Evolution of disease features over time
Differential diagnosis
Diagnosis and classification
Treatment
Outcomes
Summary
Disclosure
Juvenile Fibromyalgia
Key points
Introduction
Prevalence and clinical features of juvenile fibromyalgia
Etiology and pathogenesis
Prognosis for juvenile fibromyalgia
Evaluation of juvenile fibromyalgia in a rheumatology clinic
Diagnostic criteria for juvenile fibromyalgia
Treatment of juvenile fibromyalgia
Future research
Summary
Clinics care points
Juvenile Localized Scleroderma: Updates and Differences from Adult-Onset Disease
Key points
Introduction
Epidemiology
Pathogenesis
Patient evaluation overview: manifestations
Disease monitoring
Treatment
Summary
Clinics care points
Updates in Systemic Sclerosis Treatment and Applicability to Pediatric Scleroderma
Key points
Introduction
Medical treatment options and adjunct care
Organ system management
Vasculopathy
Summary of juvenile-onset systemic sclerosis treatment
Clinics care points
Disclosure
Recent Advances in Pediatric Vasculitis
Key points
Introduction
Large vessel vasculitis: Takayasu Arteritis
Medium vessel vasculitis
Small vessel vasculitis
Summary
Clinics care points
Disclosure
COVID-19 in Pediatrics
Key points
Coronavirus disease 2019 in children and adolescents
Multisystem Inflammatory Syndrome in Children
Future directions
Summary and Discussion
Clinics care points
Disclosure

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Laura E. Schanberg︎

Yukiko Kimura