Pandemic of Diabetes and Prediabetes: Prevention and Control, An Issue of Endocrinology and Metabolism Clinics of North America

1st Edition, Volume 50-3 - August 17, 2021
Editor: K M Venkat Narayan
Language: English
Hardback ISBN:
9 7 8 - 0 - 3 2 3 - 8 0 9 0 5 - 4
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 8 0 9 0 6 - 1

Provides in-depth, clinical reviews on diabetes and prediabetes prevention and control, providing actionable insights for clinical practice. Presents the latest inform… Read more

Pandemic of Diabetes and Prediabetes: Prevention and Control, An Issue of Endocrinology and Metabolism Clinics of North America

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Provides in-depth, clinical reviews on diabetes and prediabetes prevention and control, providing actionable insights for clinical practice.

Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.

Cover image
Title page
Table of Contents
Copyright
Contributors
Forthcoming Issues
Dedication
Foreword
Preface
Definition and Classification of Diabetes and Prediabetes and Emerging Data on Phenotypes
Key points
Diagnosis of diabetes
Intermediate hyperglycemia/prediabetes
Impaired glucose tolerance
Intermediate glycated hemoglobin
Congruence of intermediate hyperglycemia definitions
Clinics care points
An Update on the Epidemiology of Type 2 Diabetes: A Global Perspective
Key points
Introduction
Risk factors
Type 2 Diabetes Prevention Policies
Summary
Disclosure
Clinics care points
The Changing Nature of Mortality and Morbidity in Patients with Diabetes
Key points
Background
Discussion
Dynamics and diversification in diabetes-related complications
Diabetes-related multimorbidity
Clinics care points
Screening for Diabetes and Prediabetes
Key points
Introduction
Rationale for screening
Testing for hyperglycemia
Benefits of screening for hyperglycemia
Treatment of screen-detected diabetes or prediabetes
Current screening recommendations in the United States
Summary
Clinics care points
Prevention of Type 2 Diabetes
Key points
Introduction
Current evidence
Discussion
Summary
Clinics care points
Disclosures
Population-Level Approaches to Preventing Type 2 Diabetes Globally
Key points
Introduction
Population-level approaches to preventing type 2 diabetes
Cost-effectiveness of population-level approaches to preventing type 2 diabetes
Importance of natural experiments in evaluating population-based approaches
Summary
Disclaimer
Prevention of Diabetes Macrovascular Complications and Heart Failure
Key points
Introduction
Summary
Clinics care points
Disclosure
Prevention of Microvascular Complications of Diabetes
Key points
Introduction
Diabetes retinopathy
Risk factors for diabetes retinopathy
Diagnosis and classification of diabetic retinopathy
Risk factor control—evidence from clinical trials
Role of glucose-lowering drugs in diabetic retinopathy
Diabetic kidney disease
Risk factors for diabetic kidney disease
Diagnosis
Glycemic control: evidence from clinical trials
Role of glucose-lowering agents in diabetic kidney disease
Diabetic neuropathy
Risk factors for diabetic peripheral neuropathy
Glycemic control
Other considerations in diabetic neuropathy
Prevention of microvascular complications of diabetes
Clinical considerations
Special situations
Tertiary prevention
Criteria for specialist referral
Discussion
Summary
Clinical pearls in the prevention of microvascular complications of diabetes
Conflict of interest
Advances in Pharmacotherapeutics, Metabolic Surgery, and Technology for Diabetes
Key points
Introduction
Advances in pharmacotherapy for diabetes management
Advances in metabolic surgery
Advances in diabetes technology
Opportunities for change
Clinics care points
Disclosure
Ethnic Disparities in Diabetes
Key points
Introduction
Disparities in diabetes prevalence
Disparities and trends in diabetes incidence
Prevalence of prediabetes
Disparities in prevalence of gestational diabetes
Disparities in glycemic control
Trends and disparities in diabetes care in the United States
Disparities in diabetes-related complications
Disparities in diabetes-related mortality
Causes of racial/ethnic diabetes disparities
Prevention of diabetes among minority groups
Management of diabetes among racial/ethnic minorities
Summary and current needs
Clinics care points
Diabetes in Youth: A Global Perspective
Key points
Introduction
Presentation and classifications of diabetes in youth
Epidemiology
Etiology and risk factors
Management of diabetes in youth
Outcomes and complications of diabetes
Challenges and opportunities
Summary
Clinics care points
Disclosure
Emerging and Public Health Challenges Existing in Gestational Diabetes Mellitus and Diabetes in Pregnancy
Key points
Introduction
Challenges to screening
Challenges in self-management
Challenges in provider management
Challenges in the prevention of gestational diabetes mellitus and diabetes in pregnancy and treatment
Challenges in the treatment of gestational diabetes mellitus and diabetes in pregnancy
Intermediate- and long-term complications of gestational diabetes mellitus
Tackling the challenges necessitates adapting a life-course perspective
Summary
Clinics care points
Characterizing Multimorbidity from Type 2 Diabetes: Insights from Clustering Approaches
Key points
Introduction
Methods
Results
Discussion
Summary
Clinics care points
Disclosure
Anticipation of Precision Diabetes and Promise of Integrative Multi-Omics
Key points
Introduction
Heterogeneity and subgroups of type 2 diabetes mellitus
Genetic susceptibility of type 2 diabetes mellitus
Epigenetic, metabolomics, and multiomic markers of type 2 diabetes mellitus
Analytical implementation challenges in precision type 2 diabetes mellitus
Summary
Clinics care points

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K M Venkat Narayan