Pan-genomics: Applications, Challenges, and Future Prospects covers current approaches, challenges and future prospects of pan-genomics. The book discusses bioinformatics tools and their applications and focuses on bacterial comparative genomics in order to leverage the development of precise drugs and treatments for specific organisms. The book is divided into three sections: the first, an "overview of pan-genomics and common approaches,” brings the main concepts and current approaches on pan-genomics research; the second, “case studies in pan-genomics,” thoroughly discusses twelve case, and the last, “current approaches and future prospects in pan-multiomics”, encompasses the developments on omics studies to be applied on bacteria related studies. This book is a valuable source for bioinformaticians, genomics researchers and several members of biomedical field interested in understanding further bacterial organisms and their relationship to human health.
Key Features
Covers the entire spectrum of pangenomics, highlighting the use of specific approaches, case studies and future perspectives
Discusses current bioinformatics tools and strategies for exploiting pangenomics data
Presents twelve case studies with different organisms in order to provide the audience with real examples of pangenomics applicability
Readership
Bioinformaticians, genomics scientists, microbiologists, graduate students in diverse related fields
Table of Contents
1. Overview, applications, and future perspectives of Pan-genomics Siomar de Castro Soares 2. Bioinformatics approaches applied in Pan-genomics and their challenges Rommel Thiago Juca Ramos Sr. 3. Evolutionary pan-genomics and applications Basant K. Tiwary 4. Insights into old and new enemies: Pan-genomics of Corynebacterium diphtheriae and Corynebacterium ulcerans Andreas Burkovski 5. Pan-genomics of Veterinary pathogens: Corynebacterium psedotuberculosis Vasco Ariston de Carvalho Azevedo 6. Pan-genomics of Plant pathogens and its applications Rabia Amir 7. Pan-genomics food pathogens and its applications Ulisses de Padua Pereira II 8. Pan-genomics of aquatic animal pathogens and its applications Nguyen Thanh Luan and Pham Thi Hai Ha 9. Pan-genomics of model bacteria and their outcomes Amjad Ali 10. Pan-genomics of multi drug-resistant human pathogenic bacteria and their resistome Mauricio Corredor Sr. 11. Pan-genomics of Virus and its applications Luiz Alcantara 12. Pan-genomics of Fungi and its applications Aristóteles Góes-Neto 13. Pan-genomics of Algae and applications Jaspreet Kaur 14. Pan-genomics of Plants and its applications Rabia Amir 15. Pan-cancer analysis and applications Dipali Dhawan 16. Reverse vaccinology and drug target identification through Pan-genomics Amjad Ali 17. Pan-metagenomics and its applications Ranjith Kumavath Sr. 18. Pan-transcriptomics and its applications Attya Bhatti 19. Pan-proteomics and its applications Wanderson Marques 20. Pan-metabolomics and its applications Li Bao and Xiaofeng Liu 21. Pan-interactomics and its applications Dinesh Kumar Yadav
Debmalya Barh, PhD, holds Master’s and PhD’s degree on Biotechnology and Post-Doc on Bioinformatics. He is honorary Principal Scientist at Centre for Genomics and Applied Gene Technology, Institute of Integrative Omics and Applied Biotechnology, a global platform of multidisciplinary research and advocacy. He has experience with both academic and industrial research and has more than 12 years on bioinformatics and personalized diagnostic/medicine industry experience, with focus on translating academic research into high value commercial products. He has published more than 150 articles in reputed international journals and has edited 15 cutting-edge biotechnology related reference books. He has also co-authored 30+ book chapters. Due to his significant contribution in the field, he has been recognized by Who's Who in the World and Limca Book of Records.
Affiliations and Expertise
Principal Scientist, Centre for Genomics and Applied Gene Technology, Institute of Integrative Omics and Applied Biotechnology, Nonakuri, Purba Medinipur, West Bengal, India
Siomar Soares
Dr Soares holds a degree in Biomedicine, with special training in Bioinformatics, Master's Degree and PhD in Genetics by Federal University of Minas Gerais – UFMG, the latter with one year of study at the Center for Biotechnology (CeBiTec), Universität Bielefeld. He holds a Post-doctorate in Bioinformatics by UFMG. He was Senior Researcher Bioinformatics at the Central Official Laboratory of the Brazilian Ministry of Fisheries and Aquaculture (2014-2015). He is currently Professor at Federal University of the Triângulo Mineiro (UFTM) since 2015, Secretary of the Southeastern regional of the Brazilian Society of Genetics (2017-current), Substitute Coordinator of the undergraduate course in Biomedicine at UFTM (2017-current) and Substitute Research and Technology Development Coordinator of UFTM (2017-current). His research interests are molecular genetics, genomic sequencing and comparative genomics of microorganisms, focusing on pan-genomics, genomic plasticity in the identification of islands of pathogenicity and virulence factors, phylogenomics, molecular epidemiology, reverse vaccination and software development.
Affiliations and Expertise
Professor, Department of Immunology, Microbiology and Parasitology, Institute of Biological Sciences and Natural Sciences, Federal University of Triangulo Mineiro (UFTM), Brazil
Sandeep Tiwari
Dr. Tiwari obtained his BSc from Deen Dayal Upadhyaya Gorakhpur University, MSc in Bioinformatics from Devi Ahilya University, and PhD in Bioinformatics from Department of Genetics, Ecology and Evolution, Federal University of Minas Gerais, Brazil. He is Guest Associate Editorial Board of Frontier in Genetics and frequently serves as an external reviewer for PeerJ and Frontiers. His main areas of expertise are molecular genetics, genomic sequencing and comparative genomics of microorganisms, with a focus on pan-genomics, genomic plasticity in the identification of pathogenicity islands and virulence factors for drug discovery, phylogenomic, molecular epidemiology, reverse vaccinology, and immunoinformatic.
Affiliations and Expertise
Post-doctoral Research Fellow, Department of Genetics, Ecology and Evolution, Federal University of Minas Gerais
Vasco Azevedo
Vasco Azevedo is a full professor, CNPq researcher 1A, member of the Brazilian Academy of Sciences, Commander of the Order of Scientific Merit of the MCTI, of the Genetics advisory committee and the public policy working group on Biotechnology and Genetic resources of COBRG / CNPq, coordinator of the Associated International Laboratory Bact-infl from INRA and UFMG, and vice-president of the Brazilian Association of Bioinformatics and Computational Biology (AB3C). He holds a degree in Veterinary Medicine from the School of Veterinary Medicine of the Federal University of Bahia (1986), a master's degree (1989), and a doctorate (1993) in Genetics of Microorganisms from the Institut National Agronomique Paris Grignon. Post-doctorate from the Department of Microbiology, School of Medicine, University of Pennsylvania (the USA, 1994). Professor at the Institute of Biomedical Sciences of the University of São Paulo (2004) and Ph.D. in Bioinformatics at UFMG (2017). He has experience in Genetics and Bioinformatics, emphasizing Molecular and Microorganism Genetics, acting mainly on the following topics: Genomics; transcriptomics; proteomics, metabolomics; Functional analysis of genes; Virulence and pathogenicity study, Molecular Biotechnology and Biosafety. He works on vaccine development, diagnostics, and the development of next-generation probiotics.
Affiliations and Expertise
Professor, Institute of Biological Sciences, Federal University of Minas Gerais (UFMG), Brazil
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