Organophosphates Chemistry, Fate, and Effects

1st Edition

Chemistry, Fate, and Effects

Authors:

  • Patricia Levi
  • Janice Chambers
  • Organophosphates Chemistry, Fate, and Effects

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    Description

    This volume pulls together a wealth of up-to-date information on the toxicology of this diverse and ubiquitous class of insecticides. Leading experts review the reactivity of organophosphorus compounds with cholinesterase, as well as their metabolism and biological effects on humans and other nontarget organisms. The book not only covers the anticholinesterase actions of organophosphates, but also other, presumably independent, effects, such as teratogenicity, delayed neuropathy, immunotoxicity, and behavioral toxicity.

    Key Features

    @introbul:Key Features @bul:* Offers crucial overviews of chemical and biochemical reactivity and biological responsiveness of mainly nontarget organisms * Reviews new developments in assessment of metabolism and disposition of organophosphorus compounds * Examines organophosphorus compound-induced toxicity mediated by mechanisms other than inhibition of acetylcholinesterase * Covers new research on differences in toxicity induced by the variety of organophosphorus * Analyzes current controversies on the relevance of certain biochemical parameters in actual organophosphate toxicity in vivo

    Readership

    Toxicologists, pesticide chemists, environmental scientists, public health specialists, and pharmacologists.

    Table of Contents

    (Section Headings): Introduction. Metabolic Fate. Toxic Effects--Noncholinergic Biochemical. Toxic Effects--Organismal. Summary and Conclusions.

    Details

    No. of pages:
    440
    Language:
    English
    Copyright:
    © 1992
    Published:
    Imprint:
    Academic Press
    Print ISBN:
    9780121673451
    Electronic ISBN:
    9780080917269