Organogenesis in Development
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Understanding organogenesis is central to current efforts to direct stem cell differentiation and function in the context of a complex organ. Defects in organogenesis are often the major manifestations of human genetic disease syndromes. This volume describes the development of 10 major organ systems, reviewed by experts in each, to provide an up-to-date overview for researchers within and outside the field, students, teachers and clinicians.
Key Features
- Summarizes the key morphological and cellular events
- Emphasizes up-to-date research relating to molecular control mechanisms
- Draws on a range of model vertebrates and contemporary experimental approaches, including lessons learnt from human developmental disease
- Distils common themes and differences for comparative studies
- Highlights key remaining questions and sets the agenda for future research
Readership
Researchers in cell, developmental, and molecular biology; genetics
Table of Contents
- 1. How to Make a Heart: The Origin and Regulation of Cardiac Progenitor Cells
Ste´phane D. Vincent and Margaret E. Buckingham
2. Vascular Development—Genetic Mechanisms and Links to Vascular Disease
John C. Chappell and Victoria L. Bautch
3. Lung Organogenesis
David Warburton, Ahmed El-Hashash, Gianni Carraro, Caterina Tiozzo, Frederic Sala, Orquidea Rogers, Stijn De Langhe, Paul J. Kemp, Daniela Riccardi, John Torday, Saverio Bellusci, Wei Shi, Sharon R Lubkin, and Edwin Jesudason
4. Transcriptional Networks and Signaling Pathways that Govern Vertebrate Intestinal Development
Joan K. Heath
5. Kidney Development: Two Tales of Tubulogenesis
Melissa Little, Kylie Georgas, David Pennisi, and Lorine Wilkinson
6. The Game Plan: Cellular and Molecular Mechanisms of Mammalian Testis Development
Elanor N. Wainwright and Dagmar Wilhelm
7. Building Pathways for Ovary Organogenesis in the Mouse Embryo
Chia-Feng Liu, Chang Liu, and Humphrey H-C Yao
8. Vertebrate Skeletogenesis
Ve´ronique Lefebvre and Pallavi Bhattaram
9. The Molecular Regulation of Vertebrate Limb Patterning
Natalie C. Butterfield, Edwina McGlinn, and Carol Wicking
10. Eye Development
Jochen Graw
Product details
- No. of pages: 456
- Language: English
- Copyright: © Academic Press 2010
- Published: August 4, 2010
- Imprint: Academic Press
- eBook ISBN: 9780123809131
- Hardcover ISBN: 9780123809124