COVID-19 Update: We are currently shipping orders daily. However, due to transit disruptions in some geographies, deliveries may be delayed. To provide all customers with timely access to content, we are offering 50% off Science and Technology Print & eBook bundle options. Terms & conditions.
Oral Delivery of Therapeutic Peptides and Proteins - 1st Edition - ISBN: 9780128210611

Oral Delivery of Therapeutic Peptides and Proteins

1st Edition

Editors: Puneet Tyagi Anand Subramony
Paperback ISBN: 9780128210611
Imprint: Academic Press
Published Date: 1st January 2022
Page Count: 420
Sales tax will be calculated at check-out Price includes VAT/GST

Institutional Subscription

Secure Checkout

Personal information is secured with SSL technology.

Free Shipping

Free global shipping
No minimum order.

Description

Oral Delivery of Therapeutic Peptides and Proteins provides a complete overview of the journey scientists pursue to attain protein and peptide oral delivery. The book highlights the physiological challenges that must be accounted for in addition to overcoming protease inhibition and acid stability issues that are commonly mentioned in this area of research. Primary topics include formulation technologies being adopted for oral delivery of proteins and peptides, modification of actives to make them more suited for oral delivery, animal models and their shortcomings in assessing oral bioavailability, and in vitro models to simulate drug absorption and transport.

Academics and industry researchers working in formulation development and researchers and advanced students in biotechnology and pharmacy will find this a useful resource.

Key Features

  • Demonstrates how proteins and peptides transport throughout the gastrointestinal tract and how to evaluate their biological fate when encapsulated into certain delivery systems
  • Examines developing technologies to improve future oral bioavailability
  • Includes the in vitro and preclinical techniques needed for development

Readership

Academics and industry researchers working in formulation development. Researchers and advanced students in biotechnology and pharmacy

Table of Contents

  1. Formulation technologies being adopted for oral delivery of proteins and peptides
    2. Modification of actives to make them more suited for oral delivery
    3. Animal models and their shortcomings in assessing oral bioavailability
    4. In vitro models to simulate drug absorption and transport
    5. Futuristic technologies to improve oral bioavailability

Details

No. of pages:
420
Language:
English
Copyright:
© Academic Press 2022
Published:
1st January 2022
Imprint:
Academic Press
Paperback ISBN:
9780128210611

About the Editors

Puneet Tyagi

Senior Formulation Scientist, MedImmune, AstraZeneca

Affiliations and Expertise

He specializes in design and characterization of drug delivery systems such as microparticles, nanoparticles, hydrogels, micelles; formulation development, optimization, scale up and technology transfer of small molecule oral and sterile formulations in GMP/ GLP environment; design of pre-clinical efficacy and toxicology studies; development of in vivo/ in vitro models to assess efficacy of formulations, and ocular formulation design and development.

Anand Subramony

Affiliations and Expertise

Vice President, R&D, AstraZeneca

Ratings and Reviews