Opioid Hormones

Opioid Hormones

1st Edition - August 1, 2019

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  • Editor: Gerald Litwack
  • Hardcover ISBN: 9780128188583
  • eBook ISBN: 9780128188590

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Vassopressin, Volume 111, the latest release in the Vitamins and Hormones series, first published in 1943, covers the field of hormone action, vitamin action, X-ray crystal structure, physiology and enzyme mechanisms, with this release focusing on topics relating to hepcidin, bacterial infection, and iron overload, the role of heparan sulfates in hepcidin regulation, hepcidin CDNA and human gene sex hormones, growth factors and hepcidin, HFE gene polymorphisms and hereditary hemochromatosis, hepcidin and il-1beta, hepcidin-ferroportin axis, cardiomyocyte hepcidin, adipocyte iron, leptin and hepcidin, regulators of hepcidin expression, and much more.

Key Features

  • Focuses on the newest aspects of hormone action in connection with diseases
  • Lays the groundwork for the focus of new chemotherapeutic targets
  • Represents reviews on emerging areas in hormone action, cellular regulators and signaling pathways


Intense basic science to the molecular and physiological aspects of a particular disease state. The audience includes all basic scientists and clinicians interested in the focus of a given volume

Table of Contents

  • 1. Evolution of proopiomelanocortin
    Ana Rocha, Alejandra Godino-Gimeno and José Miguel Cerdá-Reverter
    2. Structure and dynamics of dynorphin peptide and its receptor
    Guillaume Ferré, Georges Czaplicki, Pascal Demange and Alain Milon
    3. Molecular aspects of delta opioid receptors
    Louis Gendron, Karim Nagi, Manel Zeghal, Patrick M. Giguère and Graciela Pineyro
    4. The role of heat shock protein 90 in regulating pain, opioid signaling, and opioid antinociception
    John M. Streicher
    5. Enkephalinase regulation
    M. Ramírez-Sánchez, I. Prieto, A.B. Segarra, M. Martínez-Cañamero, I. Banegas and M. de Gasparo
    6. Limbic circuit connectivity and the stress response: New insights into the mammalian nociceptin peptide system
    Allison Jane Fulford and Sarah Keskes
    7. Enkephalins and ACTH in the mammalian nervous system
    Ewing Duque-Díaz, Olga Alvarez-Ojeda and Rafael Coveñas
    8. Opioids and the hormone oxytocin
    Leda Kovatsi and Kakia Nikolaou
    9. Estrogens as arbiters of sex-specific and reproductive cycle-dependent opioid mechanisms
    Alan R Gintzler, Emiliya M. Storman and Nai-Jiang Liu
    10. Opioids and reproduction
    Beata Seeber, Bettina Böttcher, Elisabeth D´Costa and Ludwig Wildt
    11. Kappa opioid receptor and oligodendrocyte remyelination
    Fei Wang and Feng Mei
    12. Inhibitory role of Gi-coupled receptors on cAMP-driven cancers with focus on opioid receptors in lung adenocarcinoma and its stem cells
    Hildegard M. Schuller
    13. Prenatal ethanol exposure and enkephalinergic neurotransmission
    Milagros Méndez, Karla Hernández-Fonseca and Paula Abate

Product details

  • No. of pages: 355
  • Language: English
  • Copyright: © Academic Press 2019
  • Published: August 1, 2019
  • Imprint: Academic Press
  • Hardcover ISBN: 9780128188583
  • eBook ISBN: 9780128188590

About the Editor

Gerald Litwack

Gerald Litwack
Dr. Gerald Litwack obtained M.S. and PhD degrees from the University of Wisconsin Department of Biochemistry and remained there for a brief time as a Lecturer on Enzymes. Then he entered the Biochemical Institute of the Sorbonne as a Fellow of the National Foundation for Infantile Paralysis. He next moved to Rutgers University as an Assistant Professor of Biochemistry and later as Associate Professor of biochemistry at the University of Pennsylvania Graduate School of Medicine. After four years he moved to the Temple University School of Medicine as Professor of Biochemistry and Deputy Director of the Fels Institute for Cancer Research and Molecular Biology, soon after, becoming the Laura H. Carnell Professor. Subsequently he was appointed chair of Biochemistry and Molecular Pharmacology at the Jefferson Medical College as well as Vice Dean for Research and Deputy Director of the Jefferson Cancer Institute and Director of the Institute for Apoptosis. Following the move of his family, he became a Visiting Scholar at the Department of Biological Chemistry of the Geffen School of Medicine at UCLA and then became the Founding Chair of the Department of Basic Sciences at the Geisinger Commonwealth School of Medicine, becoming Professor of Molecular and Cellular Medicine and Associate Director of the Institute for Regenerative Medicine at the Texas A&M Health Science Center as his final position. During his career he was a visiting scientist at the University of California, San Francisco and Berkeley, Courtauld Institute of Biochemistry, London and the Wistar Institute. He was appointed Emeritus Professor and/or Chair at Rutgers University, Thomas Jefferson University and the Geisinger Commonwealth School of Medicine. He has published more than 300 scientific papers, authored three textbooks and edited more than sixty-five books. Currently he lives with his family and continues his authorship and editorial work in Los Angeles.

Affiliations and Expertise

Emeritus Professor and/or Chair at Rutgers University, Thomas Jefferson University and the Geisinger Commonwealth School of Medicine, USA; Toluca Lake, North Hollywood, California, USA

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