Obesity Hypoventilation Syndrome

Obesity Hypoventilation Syndrome: From Physiologic Principles to Clinical Practice summarizes the current state of knowledge regarding the epidemiology, physiology and treatment of obesity hypoventilation syndrome (OHS). Currently, the identification and management of OHS is suboptimal, especially in the acute setting, hence the misdiagnosis or mislabeling of the problem has a significant impact on patient outcomes. This volume brings together all aspects of assessment and management into a main resource for understanding the complex physiological and clinical consequences of this condition.

• Provides one page chapter summaries that cover epidemiology, physiology and treatment options
• Presents an easy to use reference on obesity hypoventilation syndrome, including symptoms
• Contains chapters with detailed discussions of topics, including color images, graphs and tables that summarize current research

Research scientists as well as respiratory and sleep medicine specialists

I. Historical and social introduction
1. Obesity: A social and public policy perspective
2. History of obesity hypoventilation

II. The burden of obesity on respiratory health
3. Effect of obesity on the respiratory system
4. The burden of obesity hypoventilation syndrome

III. Pathophysiology of obesity hypoventilation syndrome
5. Neural control of breathing in sleep
6. Pathogenesis of sleep apnea
7. The pathophysiology of obesity hypoventilation syndrome
8. Evolution of obesity hypoventilation syndrome
9. Cardiovascular, neurological, and inflammatory complications of obesity hypoventilation syndrome

IV. Clinical assessment of a patient with obesity hypoventilation
10. Assessment of patients with obesity hypoventilation syndrome
11. Detection of hypoventilation
12. Diagnosis of sleep-disordered breathing

V. Management of obesity hypoventilation
13. Positive airway pressure I: Equipment
14. Positive airway pressure II: Settings and outcomes
15. The effects of weight loss, tracheostomy, and medication on obesity hypoventilation syndrome
16. Weight loss: Lifestyle interventions and pharmacotherapy
17. Surgical weight loss
18. Tracheostomy in morbidly obese patients
19. Obesity hypoventilation in the intensive care unit
20. Perioperative considerations and management in patients with obesity hypoventilation syndrome