Nucleic Acid Sensing and Immunity - PART B - 1st Edition - ISBN: 9780128159811, 9780128159828

Nucleic Acid Sensing and Immunity - PART B, Volume 345

1st Edition

Serial Volume Editors: Claire Vanpouille-Box Lorenzo Galluzzi
Hardcover ISBN: 9780128159811
eBook ISBN: 9780128159828
Imprint: Academic Press
Published Date: 21st March 2019
Page Count: 374
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Table of Contents

Claire Vanpouille-Box
1. Nucleic acids sensing in allergic disorders
James Gerard Martin
2. Nucleic acids sensing in autoimmune disorders
Alan G. Goodman
3. Nucleic acid sensing in inflammatory disorders
Hasan Zaki
4. Viral nucleic acid sensing inflammasomes in intestinal host defence
Andy Wullaert
5. Genome damage sensing leads to tissue homeostasis in Drosophila
BJ Rao
6. Nucleic acids sensing in plants
Martin Heil
7. Nucleic Acid sensing in invertebrates
Wang Pei-Hui


Nucleic Acid Sensing and Immunity - PART B, Volume 345 gives a comprehensive overview of the nucleic acid machinery, from plants to mammalians, along with their regulation. Chapters in this updated volume include Nucleic acids sensing in allergic disorders, Nucleic acids sensing in autoimmune disorders, Nucleic acid sensing in inflammatory disorders, Viral nucleic acid sensing inflammasomes in intestinal host defense, Genome damage sensing leads to tissue homeostasis in Drosophila, Nucleic acids sensing in plants, Nucleic Acid sensing in invertebrates, amongst other topics.

Key Features

  • Provides an accurate, state-of-the-art resource on RNA sensing
  • Includes the work of a well-known tumor immunologist
  • Links intestinal host defense and viral nucleic acid sensing
  • Presents a chapter on the negative regulation of DNA sensing, a timely topic


Immunologists to tumor immunologists and DNA damage biologists.


No. of pages:
© Academic Press 2019
21st March 2019
Academic Press
Hardcover ISBN:
eBook ISBN:

Ratings and Reviews

About the Serial Volume Editors

Claire Vanpouille-Box

Claire Vanpouille-Box Serial Volume Editor

Claire Vanpouille-Box received her Ph.D. in Experimental Pharmacology in 2011 from the University of Angers, France. Determined to pursue an academic career and intrigued by the emerging role of radiation in cancer immunotherapy, she decided to join the lab of Dr. Demaria in 2011 to conduct her postdoctoral training. Claire is currently holding a junior faculty position as an instructor in radiation oncology at Weill Cornell Medicine where she is focusing her research to study the mechanisms whereby radiation therapy can convert a tumor into an in situ individualized vaccine. In particular, Claire is leveraging her multidisciplinary background to better understand how radiation should be administered to induce anti-tumor immunity. She has published 28 articles in peer-reviewed scientific journals and have received many prestigious awards among which the 2014-Marie Curie Award from the Radiation Research Society (RRS), the 2015-AACR Susan G Komen Scholar-in-training award from the American Association for Cancer Research (AACR) and the 2017-AAI Early Career Faculty travel grant from the American Association of Immunologists (AAI).

Affiliations and Expertise

Weill Cornell Medicine Radiation Oncology

Lorenzo Galluzzi

Lorenzo Galluzzi Serial Volume Editor

Lorenzo Galluzzi (born 1980) is currently Assistant Professor of Cell Biology in Radiation Oncology at the Department of Radiation Oncology of the Weill Cornell Medical College (New York, USA), and Honorary Associate Professor at the Faculty of Medicine of the Paris Descartes University (Paris, France). Prior to joining Weill Cornell Medical College (2017), Lorenzo Galluzzi was a Junior Scientist of the Research Team “Apoptosis, Cancer and Immunity” at the Cordeliers Research Center (Paris, France; 2012-2016). Lorenzo Galluzzi did his post-doctoral training at the Gustave Roussy Cancer Center (Villejuif, France; 2009-2011), after receiving his PhD from the Paris Sud University (Le Kremlin-Bicetre, France; 2005-2008). He is also Associate Director of the European Academy for Tumor Immunology (EATI), and Founding Member of the European Research Institute for Integrated Cellular Pathology (ERI-ICP). Lorenzo Galluzzi is best known for major experimental and conceptual contributions to the fields of cell death, autophagy, tumor metabolism and tumor immunology. In particular, he provided profound insights into the links between adaptive stress responses in cancer cells and the activation of a clinically relevant tumor-targeting immune response in the context of chemotherapy and radiation therapy. Lorenzo Galluzzi has published more than 350 scientific articles in international peer-reviewed journals. According to a survey published by Lab Times, he is currently the 6th and the youngest of the 30 most-cited European cell biologists (relative to the period 2007–2013). Lorenzo Galluzzi currently operates as Editor-in-Chief of three journals: OncoImmunology (which he co-founded in 2011), International Review of Cell and Molecular Biology, and Molecular and Cellular Oncology (which he co-founded in 2013). In addition, Lorenzo Galluzzi currently serves as Founding Editor for Microbial Cell and Cell Stress, and Associate Editor for Cell Death and Disease.

Affiliations and Expertise

Weill Cornell Medical College, USA