Nucleic Acid Research

Nucleic Acid Research

Future Development

1st Edition - November 1, 1983

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  • Editor: Kiyoshi Mizobuchi
  • eBook ISBN: 9780323144841

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Nucleic Acid Research: Future Development reflects the exchange of ideas and information among the participants of ""The Future of Nucleic Acid Research"" symposium held at Kyoto on December 1981. This publication aims to extend the ideas presented in the symposium and to provide facts that can answer various scientific questions, particularly, in molecular biology. The book is divided into five parts. It explains the structure of DNA and chromosome and the interaction of nucleic acids with proteins. It also discusses the gene organization of prokaryotes as well as the gene expressions in eukaryotes and prokaryotes. Moreover, it talks about the DNA replication and recombination prokaryotes. This publication is a masterful reference for genetics and molecular biology researchers and lecturers. It will also be an excellent learning material for students taking different courses in biology, including genetics, cell and molecular biology, molecular biophysics, and biochemistry.

Table of Contents

  • Contributors



    Part I Structure of DNA and Chromosome and Interactions of Nucleic Acids with Proteins

    Chemistry and Biology of Left-Handed Z DNA

    The Geometry of A, B, and Z DNA

    Conformational Flexibility and Its Role in the Structure of DNA

    Crystal Structure Studies on DNA Oligomers

    Nucleosome Structure and Chromatin Superstructure

    Chromatin Fine Structure Analysis of the Histone Genes of Drosophila melanogaster

    Transposons as a Means to Clone the White Locus of Drosophila

    Poly(ADP-ribosyl)ation of Nuclear Proteins

    Structural Models for DNA-Protein Recognition

    One Model for Protein Recognition of B-DNA Sequences Suggested by the Structure of Catabolite Gene Activator Protein

    Part II Gene Organization of Eukaryotes

    Genetic Origins of B and T Cell Antibodies

    Immunoglobulin Genes Move during Differentiation as Well as Evolution

    Solid-Phase Synthesis of Polydeoxyribonucleotides for Biological Applications

    Structure and Regulation of the Corticotropin β-Lipotropin Precursor Gene

    Structure and Expression of the Cloned Genes for Human Interferon-β

    Serine Proteases: A Tissue-Specific Multi-Gene Family

    Part III Gene Expression of Eukaryotes

    The SV40 72 Base Pair Repeat: An Amazing Enhancer of Eukaryotic Gene Expression

    Structure and Function of Small Ribonucleoproteins from Eukaryotic Cells

    The Structure and Regulation of Early Region 2 Encoding the DNA Replication Functions of Human Adenoviruses

    Expression of SV40 Large T Antigen in Bacteria

    Transforming Genes of RNA Tumor Viruses

    Identification, Isolation, and Characterization of Human Transforming Genes

    Part IV Gene Expression of Prokaryotes

    Flagellar Phase Variation in Salmonella: A Model System Regulated by Flip-Flop DNA Inversions

    The Molecular Basis of Spontaneous Deletions

    Versatile Expression Cloning Vehicles Using the Lipoprotein Gene of the Escherichia coli and Their Application

    Structure, Function, and Biosynthesis of E. coli Elongation Factor Tu

    A Model for the Coordinate Regulation of Ribosomal Protein Synthesis

    Part V DNA Replication and Recombination in Prokaryotes

    Regulation of ColE1 DNA Replication

    Enzyme Studies of ϕX174 DNA Replication: Structure and Function of dnaB Protein, an Essential Replication Protein in the Primosome

    RNA Priming for Discontinuous DNA Chain Elongation and for Replication Origin of Escherichia coli

    Recombination Activities of Escherichia coli RecA Protein: Synapsis and Strand Exchange

    DNA Supercoiling and DNA Topoisomerases



Product details

  • No. of pages: 602
  • Language: English
  • Copyright: © Academic Press 1983
  • Published: November 1, 1983
  • Imprint: Academic Press
  • eBook ISBN: 9780323144841

About the Editor

Kiyoshi Mizobuchi

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