This volume is a comprehensive guide to the methodologies used in the study of structural domains of cell nuclei. The text covers chromatin, the karyoskeleton, the soluble domain, and the nucleolus. It details methods that are used to isolate components from these domains and techniques used to assemble and disassemble nuclear elements. There is also coverage of three-dimensional mapping and localization of nuclear processes.
@introbul:Key Features @bul:* Provides a practical laboratory guide for studying cell nuclei
- Includes comprehensive and easy-to-follow protocols
Graduate students, technicians, postdoctoral, and experienced researchers. Cell, developmental, and molecular biologists, geneticists, human genome researchers, and others studying nuclear structure and organization.
- No. of pages:
- © Academic Press 1997
- 13th October 1997
- Academic Press
- eBook ISBN:
- Hardcover ISBN:
@qu:"Nuclear Structure and Function is remarkably up to date, and all of the authors have produced clear and very useful contributions. This handbook is highly recommended and will be essential for researchers investigating all aspects of the nucleus, from the biochemistry of specific processes through to nuclear architecture. It will also be very helpful to all those who want to use some of these techniques as part of their research, perhaps to investigate the function of a particular gene product or the control of its expression." @source:--TIBS
State University of New York, School of Medicine, University Medical Center, Stony Brook, U.S.A.