COVID-19 Update: We are currently shipping orders daily. However, due to transit disruptions in some geographies, deliveries may be delayed. To provide all customers with timely access to content, we are offering 50% off Science and Technology Print & eBook bundle options. Terms & conditions.
Nuclear Particles - 1st Edition - ISBN: 9780121476083, 9781483216805

Nuclear Particles

1st Edition

The Cell Nucleus, Vol. 8

Editor: Harris Busch
eBook ISBN: 9781483216805
Imprint: Academic Press
Published Date: 28th January 1981
Page Count: 424
Sales tax will be calculated at check-out Price includes VAT/GST
Price includes VAT/GST

Institutional Subscription

Secure Checkout

Personal information is secured with SSL technology.

Free Shipping

Free global shipping
No minimum order.


The Cell Nucleus, Volume III: Nuclear Particles, Part A covers topics on "splicing" and "processing" and on the controls of transcriptional and transport events that must be essential to cells that are either growing and/or are phenotypically differentiated. The book discusses the immunolocalization and structural organization of nascent RNP; the in situ localization of RNA structures; and the morphogenesis, cytochemistry, and putative role of perichromatin granules. The text describes transcription in the isolated nuclei; the isolation and structure of the ribonucleoprotein fibrils containing heterogeneous nuclear RNA; and low-molecular-weight nuclear ribonucleoprotein particles. The sequence, function, and role of U snRNAs of nuclear snRNPs; the maturation of low-molecular-weight RNA species; and the properties of the heterogeneous nuclear RNA-protein complexes and nuclear matrix are also encompassed. The book further tackles human antibodies to RNA-containing particles. Cellular biologists, microbiologists, pharmacologists, geneticists, and students taking related courses will find the book useful.

Table of Contents



Contents of Other Volumes

Chapter 1 Immunolocalization and Structural Organization of Nascent RNP

I. Introduction

II. Transcriptional Activities

III. Interaction of Nascent RNA Transcripts with Proteins

IV Immunological Studies on Nascent RNP Transcripts

V Ultrastructural Analysis of Nascent RNP Transcripts

VI. Functional Activities of Nascent RNP Transcripts


Chapter 2 In Situ Localization of RNA Structures

I. Introduction

II. Methods in Ultrastructural Detection of RNA

III. General Organization of Nuclear RNA Structures

IV The Border of Condensed Chromatin

V. RNA Structures Present in the Interchromatin Space

VI. The Nucleolus

VII. Conclusions


Chapter 3 Perichromatin Granules

I. Introduction

II. Morphogenesis and Fine Structure of the PCG's

III. Variations in the Number of PCG's

IV. Cytochemistry of PCG's in Situ

V. Isolation of the PCG's

VI. Putative Role of the PCG's


Chapter 4 Transcription in Isolated Nuclei

I. Introduction

II. Techniques for Isolating Nuclei

III. Transcription in Isolated Nuclei

IV. Modification of Transcriptional Activity

V. Conclusions


Chapter 5 Isolation and Structure of the Ribonucleoprotein Fibrils Containing Heterogeneous Nuclear RNA

I. Introduction

II. Isolation of hnRNP

III. The Two Classes of Units of hnRNP

IV. The Constituents of hnRNP

V. Conclusions


Chapter 6 Low-Molecular-Weight Nuclear Ribonucleoprotein Particles

I. Introduction

II. Isolation and Characterization of Low-Molecular-Weight Nuclear RNP's Containing snRNA Species (snRNP's)

III. The Presence of snRNA in hnRNP Complexes

IV. Relation of the 10 S snRNP Particles to 30-50 S Structures

V. Poly(A)-Containing Low-Molecular-Weight Nuclear RNP Particles

VI. Biological Role of snRNP's

VII. Conclusions


Chapter 7 U snRNA's of Nuclear snRNP's

I. Introduction

II. Primary Sequence of snRNA's

III. Other Studies on snRNA's

IV. Functions of snRNA's

V. Structural Homologies of snRNA's


Chapter 8 Maturation of Low-Molecular-Weight RNA Species

I. Introduction

II. Maturation


Chapter 9 Heterogeneous Nuclear RNA- Protein Complexes and Nuclear Matrix

I. Introduction

II. Properties of hnRNA-Protein Complexes

III. Heterogeneous Nuclear RNA and Small-Molecular-Weight RNA

IV. Proteins in nRNP Complexes

V. nRNP Complexes and Nuclear Matrix

VI. Models

VII. Conclusion and Prospects


Chapter 10 Human Antibodies to RNA-Containing Particles

I. Introduction

II. Ribosomes

III. Nucleoli

IV. Nuclear RNP Particles




No. of pages:
© Academic Press 1981
28th January 1981
Academic Press
eBook ISBN:

About the Editor

Harris Busch

Ratings and Reviews