Noonan Syndrome

New Insights in Noonan Syndrome provides an in-depth analysis of this disorder for pediatric endocrinologists as well as primary care providers to provide affected patients with an updated model of care and appropriate treatment. This resource examines in detail the recent advances in understanding and treating short stature in in Noonan Syndrome, as well as the latest progress in growth hormone-dependent signaling pathways involved in short stature, one of the most frequent clinical manifestations. Chapters also address how patients with Noonan Syndrome undergo more than average surgical procedures and have a great bleeding risk. Clotting and platelet defects considerably restrict the possible analgesic and anesthetic options in patients with Noonan syndrome. This is a must have reference for pediatric endocrinologists and practicing physicians.

• Accessible, up-to-date overview of the characteristics, state-of-the-art diagnostic procedures, and management of Noonan syndrome
• Offers an important resource for those physicians who are used to seeing and treating individual symptoms, rather than a disease complex, covering the important characteristics in the presence of heart anomalies and the peri-operative considerations
• Reviews multidisciplinary management as well as post-treatment management of the disease

Fellows, residents, and practitioners in endocrinology, internal medicine, primary care; biomedical researchers of endocrine disease and rare genetic diseases across biomedical disciplines, along with educated patients and parents

1. Growth Failure and Experience with Growth Hormone therapy in Noonan Syndrome
2. Cardiac Manifestations in Noonan Syndrome; Effects of Growth hormone therapy
3. Noonan Syndrome: Phenotypic Variations and Molecular Genetics
4. Urological Conditions and Treatment in Noonan Syndrome
5. Noonan Syndrome: Gastroenterology System Challenges
6. Developmental and Neurological features of Noonan Syndrome
7. Hemostatic and Coagulation Factor deficiency in Noonan Syndrome
8. Peri-Operative Considerations in Noonan Syndrome