Nitric Oxide, Part F

Nitric Oxide, Part F

1st Edition - April 25, 2008
This is the Latest Edition
  • Editors: Enrique Cadenas, Lester Packer
  • eBook ISBN: 9780080877617
  • Hardcover ISBN: 9780123739674

Purchase options

Purchase options
DRM-free (PDF)
Available
Sales tax will be calculated at check-out

Institutional Subscription

Free Global Shipping
No minimum order

Description

The discovery that nitrogen monoxide or nitric oxide (NO)is a biologically produced free radical has revolutionized our thinking about physiological and pathological processes. This discovery has ignited enormous interest in the scientific community. When generated at low levels, NO is a signaling molecule, but at high concentration, NO is a cytotoxic molecule. The physiological and pathological processes of NO production and metabolism and its targets, currently areas of intensive research, have important pharmacologic implications for health and disease.

Readership

Biochemists, molecular biologists, physiologists, pharmacologists, cell biologists, biomedical researchers, and neuroscientists.

Product details

  • No. of pages: 512
  • Language: English
  • Copyright: © Academic Press 2008
  • Published: April 25, 2008
  • Imprint: Academic Press
  • eBook ISBN: 9780080877617
  • Hardcover ISBN: 9780123739674
  • About the Serial Volume Editors

    Enrique Cadenas

    Affiliations and Expertise

    University of Southern California, Los Angeles, USA

    Lester Packer

    Lester Packer
    Lester Packer received a PhD in Microbiology and Biochemistry in 1956 from Yale University. In 1961, he joined the University of California at Berkeley serving as Professor of Cell and Molecular Biology until 2000, and then was appointed Adjunct Professor, Pharmacology and Pharmaceutical Sciences, School of Pharmacy at the University of Southern California.

    Dr Packer received numerous distinctions including three honorary doctoral degrees, several distinguished Professor appointments. He was awarded Chevalier de l’Ordre National du Merite (Knight of the French National Order of Merit) and later promoted to the rank of Officier. He served as President of the Society for Free Radical Research International (SFRRI), founder and Honorary President of the Oxygen Club of California.

    He has edited numerous books and published research; some of the most cited articles have become classics in the field of free radical biology:

    Dr Packer is a member of many professional societies and editorial boards. His research elucidated - the Antioxidant Network concept. Exogenous lipoic acid was discovered to be one of the most potent natural antioxidants and placed as the ultimate reductant or in the pecking order of the “Antioxidant Network” regenerating vitamins C and E and stimulating glutathione synthesis, thereby improving the overall cellular antioxidant defense. The Antioxidant Network is a concept addressing the cell’s redox status. He established a world-wide network of research programs by supporting and co-organizing conferences on free radical research and redox biology in Asia, Europe, and America.

    Affiliations and Expertise

    Department of Molecular Pharmacology and Toxicology, School of Pharmaceutical Sciences, University of Southern California, USA