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New Functional Biomaterials for Medicine and Healthcare - 1st Edition - ISBN: 9781782422655, 9781782422662

New Functional Biomaterials for Medicine and Healthcare

1st Edition

Authors: Elena P. Ivanova Kateryna Bazaka Russell J. Crawford
Hardcover ISBN: 9781782422655
eBook ISBN: 9781782422662
Imprint: Woodhead Publishing
Published Date: 10th December 2013
Page Count: 244
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Table of Contents

  • Author contact details
  • Woodhead Publishing Series in Biomaterials
  • Preface
  • Chapter 1: Introduction to biomaterials and implantable device design
    • Abstract:
    • 1.1 Introduction
    • 1.2 Biomaterials and their applications
    • 1.3 Biomaterial development and realisation
    • 1.4 Implantable systems design
    • 1.5 Device-associated infections
    • 1.6 Current trends in biomaterials design and fabrication
  • Chapter 2: Natural polymer biomaterials: advanced applications
    • Abstract:
    • 2.1 Introduction
    • 2.2 Chitin and chitosan
    • 2.3 Alginate
    • 2.4 Collagen
    • 2.5 Gelatin
    • 2.6 Hyaluronic acid
    • 2.7 Fibrinogen
    • 2.8 Silk fibroin
    • 2.9 Viral particles and bacteriophage capsids for drug delivery
    • 2.10 Immunocytes as ‘Trojan horses’ for molecule delivery
    • 2.11 Future trends
  • Chapter 3: Advanced synthetic polymer biomaterials derived from organic sources
    • Abstract:
    • 3.1 Introduction
    • 3.2 Poly(ester)s and poly(ester) block copolymers
    • 3.3 Poly(2-oxazoline)s
    • 3.4 Poly(alkyl carbonate)s
    • 3.5 Poly(ether)s
    • 3.6 Polypeptides
    • 3.7 Poly(anhydride)s
    • 3.8 Poly(urethane)s
    • 3.9 Conclusion
  • Chapter 4: Advanced synthetic and hybrid polymer biomaterials derived from inorganic and mixed organic–inorganic sources
    • Abstract:
    • 4.1 Introduction
    • 4.2 Synthetic inorganic polymers
    • 4.3 Silicon-based inorganic polymers
    • 4.4 Poly(phosphazene)s
    • 4.5 Organic–inorganic hybrid polymers
    • 4.6 Geopolymers
    • 4.7 Conclusion
  • Chapter 5: Metallic biomaterials: types and advanced applications
    • Abstract:
    • 5.1 Introduction
    • 5.2 Stainless steel
    • 5.3 Co-Cr alloys
    • 5.4 Ti and Ti-based alloys
    • 5.5 Noble metal alloys
    • 5.6 Shape memory alloys
    • 5.7 Biodegradable metals
    • 5.8 Conclusion
  • Chapter 6: Cytotoxicity and biocompatibility of metallic biomaterials
    • Abstract:
    • 6.1 Introduction
    • 6.2 Cytotoxicity and biocompatibility of metals and alloys
    • 6.3 Effect of load and wear on implant degradation
    • 6.4 Macrophage-mediated inflammatory events
    • 6.5 Role of bacterial endotoxins in triggering a particle-induced inflammatory response
    • 6.6 Osteoclast-mediated bone resorption
    • 6.7 Osteolysis as a function of implant-associated mechano-transduction
    • 6.8 Surface modification as a means of enhancing biocompatibility and corrosion resistance
    • 6.9 Conclusion
  • Chapter 7: Bioinert ceramic biomaterials: advanced applications
    • Abstract:
    • 7.1 Introduction
    • 7.2 Hardness, high compressive strength and wear resistance of bioinert refractory polycrystalline compounds
    • 7.3 Techniques for the fabrication of bioinert ceramic implants
    • 7.4 Conclusion
  • Chapter 8: Advanced bioactive and biodegradable ceramic biomaterials
    • Abstract:
    • 8.1 Introduction
    • 8.2 The development of bioactive ceramics for tissue engineering
    • 8.3 Calcium phosphates
    • 8.4 Bioactive glasses
    • 8.5 Conclusion
  • Index


New Functional Biomaterials for Medicine and Healthcare provides a concise summary of the latest developments in key types of biomaterials.

The book begins with an overview of the use of biomaterials in contemporary healthcare and the process of developing novel biomaterials; the key issues and challenges associated with the design of complex implantable systems are also highlighted. The book then reviews the main materials used in functional biomaterials, particularly their properties and applications. Individual chapters focus on both natural and synthetic polymers, metallic biomaterials, and bio-inert and bioactive ceramics.

Advances in processing technologies and our understanding of materials and their properties have made it possible for scientists and engineers to develop more sophisticated biomaterials with more targeted functionality. New Functional Biomaterials for Medicine and Healthcare provides an ideal one-volume summary of this important field that represents essential reading for scientists, engineers, and clinicians, and a useful reference text for undergraduate and postgraduate students.

Key Features

  • Provides a concise summary of the latest developments in key types of biomaterials
  • Highlights key issues and challenges associated with the design of complex implantable systems
  • Chapters focus on both natural and synthetic polymers, metallic biomaterials, and bio-inert and bioactive ceramics


Practicing scientists and engineers interested in biomaterials sciences


No. of pages:
© Woodhead Publishing 2013
10th December 2013
Woodhead Publishing
Hardcover ISBN:
eBook ISBN:


"The main feature of this book is the strong link between the special properties of these functional biomaterials and their application potential as medical devices. This makes the book interesting for readers coming from both research and industry..." --MRS Bulletin, Sep 2014

Ratings and Reviews

About the Authors

Elena P. Ivanova

Elena P. Ivanova is a Professor at the Swinburne University of Technology, Melbourne, Australia.

Affiliations and Expertise

Swinburne University of Technology

Kateryna Bazaka

Kateryna Bazaka is a Postdoctoral Research Fellow at the School of Engineering and Physical Sciences, James Cook University, Australia.

Affiliations and Expertise

James Cook University

Russell J. Crawford

Roy J. Crawford was Vice Chancellor of the University of Waikato, New Zealand. Prior to this he was Pro Vice-Chancellor for Research at Queen’s University Belfast in Northern Ireland, United Kingdom. At Queen’s University, Professor. Crawford was responsible for establishing the Polymer Processing Research Centre which included the Research Group on rotational moulding of plastics, which he also founded. In 1998, he was elected as a Fellow of the Royal Academy of Engineering, and in 2005 was elected as a Fellow of the Society of Plastics Engineers. In the 2015 Queen's Birthday Honours, Prof. Crawford was appointed a Companion of the New Zealand Order of Merit, for services to tertiary education. Prof. Crawford sadly passed away in 2016.

Affiliations and Expertise

Fomer Vice Chancellor, University of Waikato, Hamilton, Waikato, New Zealand