With screening and selection of biocatalysts being undervalued in Europe in comparison with USA and especially Japan, the working parties "Applied Biocatalysis" and "Microbial Physiology" of the European Federation of Biotechnology decided to organise an international symposium entitled "New Frontiers in Screening for Microbial Biocatalysts".

Novel screening techniques, microbial biodiversity, microbial physiology and molecular genetics were discussed to give better insights into possibilities and limitations of obtaining biocatalysts from nature.

These proceedings provide a comprehensive overview of the present state-of-the-art in the field of biocatalysts screening.


For scientists working within the field of biocatalysts screening.

Table of Contents

Preface. Acknowledgments. Oral Presentations. General introduction to biocatalysis and screening (K. Kieslich). Screening of novel enzymes for the production of useful compounds (H. Yamada). A Japanese screening approach: selection of an opine dehydrogenase and alkaline D-peptidase (Y. Asano). Screening and expression cloning of fungal enzyme genes of industrial relevance (H. Dalbøge). The enormous diversity and biotechnological potential of naturally occurring bacteria (E. Stackebrandt). Automated techniques in screening for microorganisms with biocatalytic properties (O. Favre-Bulle et al.). Fluorescence screening for lipolytic enzymes (A. Hermetter et al.). DRASTIC (diffuse reflectance absorbance spectoscopy taking in chemometrics). A novel, rapid, hyperspectral, FT-IR-based approach to screening for biocatalytic activity and metabolite overproduction (D.B. Kell et al.). Filtration and separation materials for analytical purposes (R.G. Hood). Time resolved fluorescence based assays in screening for biocatalytic activities (S. Webb). Screening for inhibitors of human brain myo-inositol monophosphatase (A.J. Ganzhorn et al.). Miniaturization of radioisotopic, luminescent and fluorescent assays to 384-well microplates (A.J. Kolb). Screening of bacteria at high temperatures to select nucleoside antibiotics producers (T. Utagawa). Posters. Passive and active screening of D-hydantoinase-producing microorganisms (A. Morin, D. Leblanc). High level production of 3-cyano-6-hydroxypyridine from 3-cyanopyridine by Comamonas testosteroni MCI2848 (M. Ueda et al.). Investigation of the &bgr;-glucosidases potentialities of yeast strains and application to bound aromatic terpenols liberation (Y. Gueguen et al.). Selection and study of a Candida molischiana mutant derepressed for &bgr;-glucosidase production: application to flavor development of wines and fruit juices (


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© 1998
Elsevier Science
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