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New Frontiers and Applications of Synthetic Biology presents a collection of chapters from eminent synthetic biologists across the globe who have established experience and expertise working with synthetic biology. This book offers several important areas of synthetic biology which allow us to read and understand easily. It covers the introduction of synthetic biology and design of promoter, new DNA synthesis and sequencing technology, genome assembly, minimal cells, small synthetic RNA, directed evolution, protein engineering, computational tools, de novo synthesis, phage engineering, a sensor for microorganisms, next-generation diagnostic tools, CRISPR-Cas systems, and more.
This book is a good source for not only researchers in designing synthetic biology, but also for researchers, students, synthetic biologists, metabolic engineers, genome engineers, clinicians, industrialists, stakeholders and policymakers interested in harnessing the potential of synthetic biology in many areas.
- Offers basic understanding and knowledge in several aspects of synthetic biology
- Covers state-of-the-art tools and technologies of synthetic biology, including promoter design, DNA synthesis, DNA sequencing, genome design, directed evolution, protein engineering, computational tools, phage design, CRISPR-Cas systems, and more
- Discusses the applications of synthetic biology for smart drugs, vaccines, therapeutics, drug discovery, self-assembled materials, cell free systems, microfluidics, and more
Synthetic biology researchers, students, industrialists, policymakers and stakeholders
1. An introduction and development of synthetic biology
2. Design and characterization of synthetic promoter
3. A novel DNA synthesis technology
4. Advances in DNA sequencing technology
5. Recent development in genome design and assembly tools
6. Design, building and challenges in synthetic genomics
7. Synthetic minimal cells and its applications
8. Small RNA-based systems for sensing and therapeutic applications
9. Advances in directed evolution for synthetic biology applications
10. Protein engineering as a synthetic biology tool
11. Computational tools for design of synthetic circuits
12. Artificial intelligence and machine learning in synthetic biology – added chapter based on reviewer feedback
13. De novo design and synthesis of biomolecules
14. A retro-biosynthetic approach for production of molecules
15. Engineering of phage for controlling of multidrug resistance bacteria
16. Synthetic systems for detecting of microorganisms
17. Synthetic systems for detection and targeting human diseases
18. Development of next generation diagnostic tools using synthetic biology
19. Advances and application of CRISPS-Cas systems
20. Synthetic biology for smart vaccines designing and delivery
21. Drug discovery and development using synthetic biology
22. Synthetic biology for nanotechnology and drug delivery
23. Design of self-assembled soft living materials using synthetic biology
24. Synthetic gene circuits for decision-making features
25. Advances in cell free synthetic biology
26. Xeno nucleic acids (XNA) based synthetic biology – added chapter based on reviewer feedback
27. Advances and development of microfluidics in synthetic biology
- No. of pages:
- © Academic Press 2022
- 1st January 2022
- Academic Press
- Paperback ISBN:
Dr. Vijai Singh is an Associate Professor and Dean (Research & Innovation) School of Science at Indrashil University, Rajpur, Mehsana, Gujarat, India. He was an Assistant Professor in the Department of Biological Sciences and Biotechnology at Institute of Advanced Research, Gandhinagar, India and also an Assistant Professor in the Department of Biotechnology at the Invertis University, Bareilly, India. Prior to that, he was a Postdoctoral Fellow in the Synthetic Biology Group at the Institute of Systems and Synthetic Biology, Paris, France and School of Energy & Chemical Engineering at the Ulsan National Institute of Science and Technology, Ulsan, South Korea. He received his Ph.D. in Biotechnology (2009) from the National Bureau of Fish Genetic Resources, Uttar Pradesh Technical University, Lucknow, India. During his PhD, he has cloned, expressed and characterized hemolysin from Aeromonas hydrophila in Escherichia coli. He has extensive experience in Synthetic Biology including MAGE, small regulatory RNAs, pathway designing, CRISPR-Cas systems, and microfluidics. His research interests are focused on building novel biosynthetic pathways for production of medically and industrially important biomolecules. Additionally, his laboratory is working on CRISPR-Cas9 tools for genome editing. He has more than 9 years of research and teaching experience in synthetic biology, metabolic engineering, microbiology, and industrial microbiology. He has published 76 articles, 40 chapters, 10 books and 2 patents. He serves as an associate editor, editorial board member and reviewer of a number of peer-reviewed journals. He is also a member of the Board of Study and Academic Council of Indrashil University and is the Member Secretary of Institutional Biosafety Committee (IBSC) in the same University.
Department of Biosciences, School of Science, Indrashil University, Rajpur, Mehsana, Gujarat, India
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