Neuroscience Perspectives provides multidisciplinary reviews of topics in one of the most divers and rapidly advancing fields in the life sciences. Whether you are a new recruit to neuroscience, or an established expert, look to this series for 'one-stop' sources of the historical, physiological, pharmacological, biochemical, molecular biological, and therapeutic aspects of chosen research areas.


Ideal for research-level neuroscientists, pharmacologists, and neurologists from post-graduate to senior scientists in academia and industry. There is also potential for special sales to pharmaceutical companies.

Table of Contents

Oxidant Stress: J.M.C. Gutteridge and B. Halliwell, Oxidative Stress, Brain Iron, and Neurodegeneration: Basic Principles. P. Jenner and C.W. Olanow, Pathological Evidence for Oxidative Stress in Parkinson's Disease and Related Degenerative Disorders. K. Kieburtz and I. Shoulson, Treatment of Parkinson's Disease with Deprenyl (Selegiline) and Other Mondamine Oxidase Inhibitors. C.W. Olanow and M.B.H. Youdim, Iron and Nuerodegeneration: Prospects for Neuroprotection. R.A. Floyd and J.M. Carney, Nitrone Radical traps (NRTs) Protect in Experimental Neurodegenerative Diseases. M. Flint Beal, Therapeutic Effects of NOS Inhibition in Neuronal Injury. Mitochodrial Toxicity: A.H.V Schapira, Mitochondrial Dysfunction in Neurodegeneration: Prospects for Neuroprotection. Excitatory Neurotoxicity: J.G. Greene and J.T. Greenamyre, Bioenergetics and Exitotoxicity: The Weak Excitotoxic Hypothesis. Calcium Exitatory Toxicity: P. Nicotera and S. Orrenius, Calcium Ions in Necrotic and Apoptotic Cell Death. Trophic Factors: C.A. Altar, S.J. Wiegand, R.M. Lindsay, and J.M. Cedarbaum, Neurotrophic Factors: Towards a Restorative Therapy of Parkinson's Disease. Immune Mechanisms: S.H. Appel, R.G. Smith, and W.D. Le, Immuno-Mediated Cell Death and Neuroprotection in Neurodegenerative Diseases. Apoptosis: W.G. Tatton, M.Y.H. Ju, J. Wadia, and N.A. Tatton, Reduction of Neuronal Apoptosis by Small Molecules: Promise for New Approaches to Neurological Therapy. Subject Index.


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© 1996
Academic Press
eBook ISBN:
Print ISBN:
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About the series-volume-editors

C. Olanow

Affiliations and Expertise

Mount Sinai Medical Center, New York, U.S.A.

Peter Jenner

Affiliations and Expertise

King's College, London, U.K. Head of Pharmacology and Therapeutics Division

Moussa Youdim

Affiliations and Expertise

Technion-Israel Institute of Technology, Haifa, Israel


@qu:"...contain[s] some well written chapters which are not only informative, up to date but also thought stimulating and will be a regular source of reference for anyone owning this book." @source:--FREE RADICAL RESEARCH