COVID-19 Update: We are currently shipping orders daily. However, due to transit disruptions in some geographies, deliveries may be delayed. To provide all customers with timely access to content, we are offering 50% off Science and Technology Print & eBook bundle options. Terms & conditions.
Naturally Occurring Bioactive Compounds - 1st Edition - ISBN: 9780444522412, 9780080464923

Naturally Occurring Bioactive Compounds, Volume 3

1st Edition

Series Volume Editors: Mahendra Rai Maria Carpinella
Hardcover ISBN: 9780444522412
eBook ISBN: 9780080464923
Imprint: Elsevier Science
Published Date: 25th September 2006
Page Count: 514
Sales tax will be calculated at check-out Price includes VAT/GST
Price includes VAT/GST

Institutional Subscription

Secure Checkout

Personal information is secured with SSL technology.

Free Shipping

Free global shipping
No minimum order.

Table of Contents

Preface to the Series


Chapter 1 Natural compounds as antioxidant and molting inhibitors can play a role as a model for search of new botanical pesticides


Insecticidal or IGR (insect growth regulator) activity

Experimental part


Concluding remarks

Future perspectives

Chapter 2 Pesticides based on plant essential oils: from traditional practice to commercialization


Sources and chemistry of essential oils

Biological activity

Commercial products and uses

Conclusion and future prospects

Chapter 3 Natural substrates and inhibitors of multidrug resistant pumps (MDRs) redefine the plant antimicrobials


The quest for natural substrates – rationale

MDR inhibitors – proof of principle

MDR mutants and inhibitors valuable tools for natural drug discovery

A new series of promising plant antimicrobials

Natural MDR inhibitors from plants – an increasing body of evidence, 5′ methoxyhydnocarpin and synergy in Berberis plants

Inhibitors against MFS MDRs

Inhibitors against ABC transporters

Conclusions and future perspectives

Chapter 4 New concept to search for alternate insect control agents from plants




Chapter 5 Role of Melia azedarach L. (Meliaceae) for the control of insects and acari: present status and future prospects



Laboratory assays

Conclusion and future prospects

Chapter 6 Bioactivity of fabaceous plants against food-borne and plant pathogens: potentials and limitations


Antimicrobial activities of some important fabaceous plants

Antimicrobials for management of phytopathogens

Future directions and conclusions

Chapter 7 Screening of plants against fungi affecting crops and stored foods


Fungi as contaminants of crops and foods

History of the use of antifungal compounds

Interaction of plant products with fungi

Plant synthesis of light-activated compounds

Factors affecting plant synthesis of bioactive compounds



Plant analysis

Cell culture analysis

Isolated compounds

Assay procedure

Results and discussion

Plant extracts

Cell cultures


Isolated compounds

Conclusions and future perspectives

Chapter 8 Opportunities and potentials of botanical extracts and products for management of insect pests in cruciferous vegetables


Azadirachtin and related products from Azadirachta indica A. Juss

Spiro enol ether analogues and extracts from Chrysanthemum coronarium L.

Extracts from Daphne tangutica Maxim.

Rotenoids and extracts from Derris spp.

Rotenoids and extracts from Tephrosia vogelii (Hook f.)

Toosendanin and extracts from Melia azedarach and M. toosendan

Parthenin, argentatins, and extracts from Parthenium spp.

Rhodojaponin and extracts from Rhododendron molle G. Don

Alkaloids and extracts from Sophora alopecuroids L.

Extracts from Stellera chamaejasme L.

Extracts from Strophanthus divaricatus (Lour.) Hooker & Arnnott

Extracts from Tripterygium wilfordii Hook. F. and T. hypoglaucum (level) Hutch.

Extracts from Xanthium sibiricum Patrin ex Widder


Final remark: the pros and cons of botanical insecticides

Chapter 9 The potential for using neem (Azadirachta indica A. Juss) extracts for pine weevil management in temperate forestry


UK forestry

The pine weevil Hylobius abietis – life cycle and pest status

Pine weevil pest management techniques – insecticides

The potential of neem extracts for pest management

Neem extracts, pine weevil management and forestry

Laboratory experiments with neem-based extracts

Field experiments with neem-based extracts

Future perspectives and conclusions

Chapter 10 Plant allelochemicals in thrips control strategies


The role of plant allelochemicals in host selection of Thysanoptera

Perception of plant allelochemicals

Methods for testing the biological activity of plant allelochemicals on thrips

Search for phytochemicals attractive to thrips

Strategies for use of attractants in thrips control

Search for repellent plant volatiles

Feeding and oviposition deterrents

Strategies for use of repellents and deterrents in thrips control

Concentration of allelochemicals

Acute and chronic toxicity of plant allelochemicals to thrips

Conclusions and future prospects

Chapter 11 Importance of plant secondary metabolites for protection against insects and microbial infections


Function of secondary metabolites

Modes of action

The dilemma of crop plants

Biorational control of herbivores and microbial infections

Conclusions and future perspectives

Chapter 12 Naturally occurring house dust mites control agents: development and commercialization


Human health importance of house dust mites

House dust mite habitat

Market of house dust mite control agents

Acaricidal activity of plant-derived materials

Poisoning symptoms and mode of action of plant-derived materials

Plant-based mite repellents

Plant-based denaturing agents of dust mite allergens

Commercialization of botanical mite control agents

Future perspectives


Chapter 13 The search for plant-derived compounds with antifeedant activity


Classes of compounds with antifeedant activity

Diversity of angiosperms with antifeedant activity (Figure 1)


Chapter 14 An overview of the antimicrobial properties of Mexican medicinal plants


Larrea tridentata (Gobernadora)


L. (Epazote)

Tagetes erecta (Cempasúchitl)

(Chechén negro)

Agave lechuguilla Torrey (lechuguilla)

spp. (Chile)

Lophophora williamsii (Lem.) Coult. (Peyote)

Yucca spp. (Palma del desierto)



Bursera simaruba (Almácigo blanco)

Chapter 15 Promissory botanical repellents/deterrents for managing two key tropical insect pests, the whitefly Bemisia tabaci and the mahogany shootborer Hypsipyla grandella


Tropical biodiversity as a source of bioactive substances against insects

Insecticides or repellents/deterrents?

The target pests: why these ones?

Methodological approaches


Concluding remarks

Chapter 16 Naturally occurring anti-insect proteins: current status and future aspects


Thiol methyltransferases



Ribosome inactivating proteins




α-Amylase inhibitors

Protease inhibitors

Glycoprotein toxin of Bacillus thuringiensis

Peptide toxins from venom of the Chinese bird spider Selenocosmia huwena Wang (also known as Ornithoctonus huwena Wang) (Theraphosidae)

Insect-sensitive scorpion toxins

Conclusion and future perspectives

Chapter 17 Antifungal natural products: assays and applications


Fungicides in agriculture

Antifungal molecules in biotic interactions

Assay procedures



Subject Index


This timely book provides an overview of natural products/botanicals used for the management of insect-pest and diseases. It will help readers to update and widen their knowledge about natural products and their bio-activities against plant pathogens. The volume explores activity, chemistry, toxicity and geographic distribution of plants. Discussions concerning the methodology used for the detection of active principles, their mode of action and commercial prospects are of utmost importance and worthy of note.

Key Features

  • Focuses on recent achievements in natural bio-actives
  • Global coverage of natural products / plants
  • Targets the most important issues of natural botanicals/ biocides
  • Includes innovative ideas with lucid explanations
  • Contains specialized chapters, such as, natural control of multi-drug resistant organisms, anti-salmonella agents, natural house-dust-mite control agents, and naturally occurring anti-insect proteins, etc.
  • Covers research on bioactives: From Lab to Field and Field to Market
  • Includes eco-friendly and economically viable herbal technology


Phytochemists; Combinatorial Chemists; Pharmacologists; Scientists engaged in Drug discovery and development; Industrial research groups developing drugs from plants; Departments of pharmaceutics; Institutes for Drug Research; Pharmaceutical companies; Manufacturers of herbal and ayurvedic medicines and cosmetic products Manufacturers of natural products


No. of pages:
© Elsevier Science 2006
25th September 2006
Elsevier Science
Hardcover ISBN:
eBook ISBN:

Ratings and Reviews

About the Series Volume Editors

Mahendra Rai

Mahendra Rai

Dr Mahendra Rai is Professor and Head of the Department of Biotechnology at Amravati University in Maharashtra, India. He has approximately three decades of teaching and research experience. The main focus of his research is plant and nano-based bioactives against human pathogenic microbes.

Affiliations and Expertise

Professor, Department of Biotechnology, Amravati University, Amravati, Maharashtra, India Head, Department of Biotechnology, Amravati University, Amravati, Maharashtra, India

Maria Carpinella

Affiliations and Expertise

Fine Chemicals and Natural Products Laboratory, School of Chemistry, Catholic University of Cordob, Argentina