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Nanoparticle Therapeutics - 1st Edition - ISBN: 9780128207574

Nanoparticle Therapeutics

1st Edition

Production Technologies, Types of Nanoparticles, and Regulatory Aspects

Editors: Prashant Kesharwani Kamalinder Singh
Paperback ISBN: 9780128207574
Imprint: Academic Press
Published Date: 12th November 2021
Page Count: 672
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Nanoparticle therapeutics: Production Technologies, Types of Nanoparticles, and Regulatory Aspects employs unique principles for applications in cell-based therapeutics, diagnostics and mechanistics for the study of organ physiology, disease etiology and drug screening of advanced nanoparticles and nanomaterials. The book focuses on the extrapolation of bioengineering tools in the domain of nanotechnology and nanoparticles therapeutics, fabrication, characterization and drug delivery aspects. It acquaints scientists and researchers on the experiential and experimental aspects of nanoparticles and nanotechnology to equip their rational application in various fields, especially in differential diagnoses and in the treatment of diverse diseased states.

This complete resource provides a holistic understanding of the principle behind formation, characterization, applications, regulations and toxicity of nanoparticles employing myriad principles of nanotechnology. Investigators, pharmaceutical researchers, and advanced students working on technology advancement in the areas of designing targeted therapies, nanoscale imaging systems and diagnostic modalities in human diseases where nanoparticles can be used as a critical tool for technology advancement in drug delivery systems will find this book useful.

Key Features

  • Brings together the novel applications of nanotechnology in biological fields
  • Explores perspectives on technologies through highly organized tables, illustrative figures and flow charts
  • Addresses key multidisciplinary challenges faced by nanotechnologists to foster collaboration among biologists, chemists, physicists, engineers and clinicians


Industrial, doctoral, post-doctoral and early career researchers working in the field of nanoparticles. Investigators, pharmaceutical researchers, innovators, and scientists working on technology advancement in the areas of designing targeted therapies, nanoscale imaging systems and diagnostic modalities in human diseases where nanoparticles can be used as a critical tool for technology advancement in drug delivery systems

Table of Contents

Part 1: Synthesis and characterization of NP for drug delivery
1. Nanoparticles: Recent state-of-art and prospective challenges
2. Fabrication, process technologies and challenges in development of nanoparticles
3. In vitro and physicochemical characterization of nanoparticles
4. Surface-engineering of nanoparticles for imparting multifunctionality
5. Biofate and cellular interactions of nanoparticles
6. Pharmacokinetics and in vivo evaluation of nanoparticles

Part 2: Application of Nanoparticles in Drug Delivery
7. Biodegradable polymeric nanoparticles for sustained drug delivery
8. Lipidic nanoparticles with improved biopharmaceutical attributes
9. Protein-based nanoparticles for drug delivery
10. Gold and silver nanoparticles for drug delivery
11. Mesoporous silica and silicates nanoparticles for drug delivery
12. Targeted nanosuspensions for improved therapeutics
13. SPIONS as therapeutic and diagnostic agents
14. Bio-inspired nanoparticles/exosomes vesicles as drug delivery vehicles

Part 3: Environmental and Regulatory Aspects
14. Regulatory pathways and federal perspectives on nanoparticles
15. Environmental hazards associated with nanoparticles
16. Biological toxicity of nanoparticles


No. of pages:
© Academic Press 2021
12th November 2021
Academic Press
Paperback ISBN:

About the Editors

Prashant Kesharwani

Dr. Prashant Kesharwani is Assistant Professor of Pharmaceutics at the School of Pharmaceutical Education and Research, Jamia Hamdard University, New Delhi, India. He has published more than 150 articles in well reputed international journals and edited 10 international books. Dr. Kesharwani has received several awards, including the ‘Ramanujan Fellowship, DST, India-2017’, ‘Excellence Research Award 2014’, ‘Young Innovator Award (Gold medal) 2012’, ‘International Travel Award/Grant from DST (New Delhi) and INSA (CCSTDS, Chennai) 2012’, as well as receiving an ICMR Senior Research Fellowship (PhD) and AICTE Junior Research Fellowship (M. Pharm.). He has presented invited talks and presentations at prestigious conferences, supervised students/junior researchers, and actively participated in outreach and scientific dissemination for the service of the wider community. Dr. Kesharwani’s current research is focused on the development of nano-engineered drug delivery systems for various diseases.

Affiliations and Expertise

Assistant Professor, Department of Pharmaceutics, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, India

Kamalinder Singh

Prof Kamalinder K Singh is Professor of Pharmaceutical Technology & Drug Delivery and Research Lead at the School of Pharmacy and Biomedical Sciences, University of Central Lancashire, Preston, United Kingdom and heads the Nanomedicine and Innovative technologies research group within the Faculty of Clinical and Biomedical Sciences and is Healthcare Lead for UCLan Centre of Smarts Materials. With more than 35 years’ experience in academia, Prof Singh has contributed significantly to the field of pharmaceutical technology, drug delivery and nanomedicine through authorship of over 80 research articles, 18 patents, 12 book chapters and 60 monographs. Her pioneering research has led to development of many biocompatible nanoparticle-based platform technologies exploiting to deliver drugs across various biological barriers with application to human health and diseases. Prof Singh serves on International Steering Committee for ‘Handbook of Pharmaceutical Excipients’, joint publication by AAPS, Pharmaceutical Press, and Royal Pharmaceutical Society, Great Britain. She has provided leadership to 35 major funded research projects and is currently managing several research projects funded by National Institute of Health, Academy of Medical Sciences, British Council and UK Foreign Commonwealth and Development Office. She has supervised 30 ECRs and delivered more than 70 keynotes and invited talks at prestigious forums around the globe.

Affiliations and Expertise

Professor of Pharmaceutical Technology and Drug Delivery, School of Pharmacy and Biomedical Sciences, Faculty of Clinical and Biomedical Sciences, University of Central Lancashire, Preston, UK

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