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Nanoparticle therapeutics: Production Technologies, Types of Nanoparticles, and Regulatory Aspects employs unique principles for applications in cell-based therapeutics, diagnostics and mechanistics for the study of organ physiology, disease etiology and drug screening of advanced nanoparticles and nanomaterials. The book focuses on the extrapolation of bioengineering tools in the domain of nanotechnology and nanoparticles therapeutics, fabrication, characterization and drug delivery aspects. It acquaints scientists and researchers on the experiential and experimental aspects of nanoparticles and nanotechnology to equip their rational application in various fields, especially in differential diagnoses and in the treatment of diverse diseased states.
This complete resource provides a holistic understanding of the principle behind formation, characterization, applications, regulations and toxicity of nanoparticles employing myriad principles of nanotechnology. Investigators, pharmaceutical researchers, and advanced students working on technology advancement in the areas of designing targeted therapies, nanoscale imaging systems and diagnostic modalities in human diseases where nanoparticles can be used as a critical tool for technology advancement in drug delivery systems will find this book useful.
- Brings together the novel applications of nanotechnology in biological fields
- Explores perspectives on technologies through highly organized tables, illustrative figures and flow charts
- Addresses key multidisciplinary challenges faced by nanotechnologists to foster collaboration among biologists, chemists, physicists, engineers and clinicians
Industrial, doctoral, post-doctoral and early career researchers working in the field of nanoparticles. Investigators, pharmaceutical researchers, innovators, and scientists working on technology advancement in the areas of designing targeted therapies, nanoscale imaging systems and diagnostic modalities in human diseases where nanoparticles can be used as a critical tool for technology advancement in drug delivery systems
Part 1: Synthesis and characterization of NP for drug delivery
1. Nanoparticles: Recent state-of-art and prospective challenges
2. Fabrication, process technologies and challenges in development of nanoparticles
3. In vitro and physicochemical characterization of nanoparticles
4. Surface-engineering of nanoparticles for imparting multifunctionality
5. Biofate and cellular interactions of nanoparticles
6. Pharmacokinetics and in vivo evaluation of nanoparticles
Part 2: Application of Nanoparticles in Drug Delivery
7. Biodegradable polymeric nanoparticles for sustained drug delivery
8. Lipidic nanoparticles with improved biopharmaceutical attributes
9. Protein-based nanoparticles for drug delivery
10. Gold and silver nanoparticles for drug delivery
11. Mesoporous silica and silicates nanoparticles for drug delivery
12. Targeted nanosuspensions for improved therapeutics
13. SPIONS as therapeutic and diagnostic agents
14. Bio-inspired nanoparticles/exosomes vesicles as drug delivery vehicles
Part 3: Environmental and Regulatory Aspects
14. Regulatory pathways and federal perspectives on nanoparticles
15. Environmental hazards associated with nanoparticles
16. Biological toxicity of nanoparticles
- No. of pages:
- © Academic Press 2021
- 1st March 2021
- Academic Press
- Paperback ISBN:
Dr. Prashant Kesharwani is Assistant Professor, Department of Pharmaceutics, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, India. He is a recipient of several internationally acclaimed awards viz “Ramanujan Fellowship, DST, India-2017”, “Excellence Research Award-2014”, “Young Innovator Award (Gold medal)-2012”, “International Travel Award/Grant from DST (New Delhi), and INSA (CCSTDS, Chennai)-2012”. He has received ICMR Senior Research Fellowship (in PhD) and AICTE Junior Research Fellowship (in M. Pharm.). After his doctorate, he worked as postdoctoral fellows in the Wayne State University, Detroit (Michigan, USA). Dr. Kesharwani subsequently joined the School of Pharmacy, International Medical University (Malaysia) as lecturer in Pharmaceutical Technology. Subsequently he joined Central Drug Research Institute (CDRI), Lucknow as Ramanujan Fellow. Dr. Kesharwani is a co-author on more than 120 publications in high impact factor international journals and multiple international books.
Assistant Professor, Department of Pharmaceutics, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, India
Prof Kamalinder K Singh is Professor of Pharmaceutical technology and drug delivery within the School of Pharmacy and Biomedical Sciences at University of Central Lancashire (UCLan). She obtained M.Pharm (Pharmaceutics) from Panjab University and Ph.D from SNDT Women’s University. She joined as faculty member at SNDT Women’s University before joining her current Position at UCLan. Presently she leads the Nanomedicine and Innovative technologies research group at UCLan within the faculty of Clinical and biomedical Sciences. Prof Singh serves on International Steering Committee for “Handbook of Pharmaceutical Excipients”, joint publication by AAPS, Pharmaceutical Press, and Royal Pharmaceutical Society, Great Britain. She has contributed 5 monographs 5th edition, 10 monographs 6th edition, 15 monographs 7th edition and 15 monographs 8th edition (2017). She has co-edited two books, authored 8 book chapters and has more than 75 peer reviewed research publications.
Professor of Pharmaceutical Technology and Drug Delivery, School of Pharmacy and Biomedical Sciences, Faculty of Clinical and Biomedical Sciences
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