To provide an interdisciplinary readership with the necessary toolkit to work with micro- and nanofluidics, this book provides basic theory, fundamentals of microfabrication, advanced fabrication methods, device characterization methods and detailed examples of applications of nanofluidics devices and systems. Case studies describing fabrication of complex micro- and nanoscale systems help the reader gain a practical understanding of developing and fabricating such systems. The resulting work covers the fundamentals, processes and applied challenges of functional engineered nanofluidic systems for a variety of different applications, including discussions of lab-on-chip, bio-related applications and emerging technologies for energy and environmental engineering.

Key Features

  • The fundamentals of micro- and nanofluidic systems and micro- and nanofabrication techniques provide readers from a variety of academic backgrounds with the understanding required to develop new systems and applications.
  • Case studies introduce and illustrate state-of-the-art applications across areas, including lab-on-chip, energy and bio-based applications.
  • Prakash and Yeom provide readers with an essential toolkit to take micro- and nanofluidic applications out of the research lab and into commercial and laboratory applications.


Professionals, commercial R&D, graduate students and academic researchers involved in the research and development of micro- and nano-fluidics.

Table of Contents


About the Authors


Nomenclature List


Common Abbreviations

Chapter 1. Introduction

1.1 Length scales

1.2 Scope and layout of the book

1.3 Future outlook


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Chapter 2. Fundamentals for Microscale and Nanoscale Flows

2.1 Introduction

2.2 Definition of a fluid

2.3 Pressure-driven flows

2.4 Low Reynolds number flows

2.5 Electrokinetic phenomena

2.6 The electric double layer

2.7 Debye length

2.8 Electrokinetic phenomena: revisited

2.9 Coupling species transport and fluid mechanics

2.10 Numerical simulations and advanced modeling methods


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Chapter 3. Interfaces in Microfluidic and Nanofluidic Systems

3.1 Introduction

3.2 Introduction to surfaces

3.3 Surface charge

3.4 Surface energy

3.5 Thermodynamics of surfaces

3.6 Surface characterization methods with relevance to microfluidics and nanofluidics

3.7 Surface tension-driven flows

3.8 Device interfaces


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Chapter 4. Advanced Fabrication Methods and Techniques

4.1 Introduction to micro- and nanofabrication

4.2 Advanced patterning techniques

4.3 Materials in micro- and nanofluidics

4.4 Fabrication case study


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Chapter 5. Lab-on-a-Chip and Fluid Manipulation Applications

5.1 Introduction

5.2 Fluid manipulation

5.3 Microvalves and nanovalves

5.4 Micropumps and nanopumps

5.5 On-chip separations and combinations

5.6 Transport and analysis systems for DNA

5.7 Biosensors

5.8 Nanomedicine and nanobiotechnology

5.9 Instrumentation and platforms at the microscale and nanoscale


No. of pages:
© 2014
William Andrew
eBook ISBN:
Print ISBN:
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About the authors

Shaurya Prakash

Affiliations and Expertise

Assistant Professor, Mechanical & Aerospace Engineering, Ohio State University

Junghoon Yeom

Affiliations and Expertise

NRC Research Associate, Naval Research Laboratory, Washington D.C.