Nanobiomaterials in Medical Imaging - 1st Edition - ISBN: 9780323417365, 9780323417389

Nanobiomaterials in Medical Imaging

1st Edition

Applications of Nanobiomaterials

Editors: Alexandru Grumezescu
eBook ISBN: 9780323417389
Hardcover ISBN: 9780323417365
Imprint: William Andrew
Published Date: 27th April 2016
Page Count: 518
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Description

Nanobiomaterials in Medical Imaging presents the latest developments in medical exploratory approaches using nanotechnology. Leading researchers from around the world discuss recent progress and state-of-the-art techniques.

The book covers synthesis and surface modification of multimodal imaging agents, popular examples of nanoparticles and their applications in different imaging techniques, and combinatorial therapy for the development of multifunctional nanocarriers. The advantages and potential of current techniques are also considered.

This book will be of interest to postdoctoral researchers, professors and students engaged in the fields of materials science, biotechnology and applied chemistry. It will also be highly valuable to those working in industry, including pharmaceutics and biotechnology companies, medical researchers, biomedical engineers and advanced clinicians.

Key Features

  • A valuable resource for researchers, practitioners and students working in biomedical, biotechnological and engineering fields
  • A detailed guide to recent scientific progress, along with the latest application methods
  • Presents innovative opportunities and ideas for developing or improving technologies in nanomedicine and medical imaging

Readership

Academic: Materials science, biotechnology and applied chemistry professors, PhD, MsC, postdocs, upper level undergraduate students. Industry: Pharmaceutics and biotechnology companies, medical researchers, biomedical engineers, advanced clinicians

Table of Contents

  • List of contributors
  • Preface of the series
  • Preface
    • About the Series (Volumes I–XI)
    • About Volume VIII
  • Chapter 1. Specifically targeted imaging using functionalized nanoparticles
    • Abstract
    • 1.1 Introduction
    • 1.2 Functionalized Quantum Dots for Imaging
    • 1.3 Functionalized Iron Oxide Nanoparticles for Imaging
    • 1.4 Functionalized Silver Nanoparticles for Imaging
    • 1.5 Conclusions
    • References
  • Chapter 2. Photon and electron interactions with gold nanoparticles: A Monte Carlo study on gold nanoparticle-enhanced radiotherapy
    • Abstract
    • 2.1 Introduction
    • 2.2 Gold Nanoparticle-Enhanced Radiotherapy
    • 2.3 Monte Carlo Simulation
    • 2.4 Photon and Electron Interactions
    • 2.5 Conclusions
    • Acknowledgments
    • References
  • Chapter 3. Quantum dots: Dynamic tools in cancer nanomedicine
    • Abstract
    • 3.1 Introduction
    • 3.2 Characteristic Features of Quantum Dots
    • 3.3 Composition of Quantum Dots
    • 3.4 Architecture of Multifunctional Quantum Dots
    • 3.5 Synthesis and Functionalization of QDs
    • 3.6 Quantum Dots in Cancer Therapy
    • 3.7 Quantum-Dot-Based Photodynamic Therapy (PDT)
    • 3.8 Toxicity Concerns
    • 3.9 Future Prospects
    • 3.10 Conclusions
    • References
  • Chapter 4. Basics to different imaging techniques, different nanobiomaterials for image enhancement
    • Abstract
    • 4.1 Introduction
    • 4.2 Basics of Different Imaging Techniques
    • 4.3 Imaging Agents
    • 4.4 Different Nanobiomaterials for Image Enhancement
    • 4.5 Miscellaneous
    • 4.6 Conclusions and Outlook
    • References
  • Chapter 5. Design of plasmonic probes through bioconjugation and their applications in biomedicine: From cellular imaging to cancer therapy
    • Abstract
    • 5.1 Introduction
    • 5.2 Optical Properties of Metal Nanoparticles
    • 5.3 Synthesis and Functionalization of Plasmonic Nanoparticles
    • 5.4 Applications in Biomedicine
    • 5.5 Conclusions
    • Acknowledgments
    • References
  • Chapter 6. Multifunctional nanocarriers for codelivery of nucleic acids and chemotherapeutics to cancer cells
    • Abstract
    • 6.1 Introduction
    • 6.2 Design of Multifunctional Delivery Systems for Drug–Gene Coadministration
    • 6.3 Multifunctional Nanomaterials for Codelivery of Drug–Nucleic Acid Combinations
    • 6.4 Conclusions and Future Perspectives
    • References
  • Chapter 7. Targeting and imaging of cancer cells using nanomaterials
    • Abstract
    • 7.1 Introduction
    • 7.2 Quantum Dots
    • 7.3 Dendrimers
    • 7.4 Magnetic Nanoparticles (MNPs)
    • 7.5 Colloidal Gold Nanoparticles
    • 7.6 Carbon-Based Nanomaterials
    • 7.7 Liposomal Nanocarriers
    • 7.8 Conclusions and Future Directions
    • References
  • Chapter 8. Multimodal inorganic nanoparticles for biomedical applications
    • Abstract
    • 8.1 Introduction
    • 8.2 Types of Multimodal Inorganic Nanoparticles
    • 8.3 Toxicological Considerations and Surface Modification of Multimodal Inorganic Nanoparticles
    • 8.4 Biomedical Applications of Multimodal Inorganic Nanoparticles
    • 8.5 Summary and Future Outlook
    • Acknowledgments
    • References
  • Chapter 9. Iron oxide nanomaterials for functional imaging
    • Abstract
    • 9.1 Introduction
    • 9.2 Iron Oxide Nanoparticles as Contrast Agents in Noninvasive Imaging Diagnosis
    • 9.3 Functionalized Iron Oxide Nanoparticles for Imaging Diagnosis
    • 9.4 Conclusions
    • References
  • Chapter 10. Nanobiomaterials involved in medical imaging technologies
    • Abstract
    • 10.1 Introduction
    • 10.2 Medical Imaging Technology
    • 10.3 Nanobiomaterials in Medical Imaging
    • 10.4 Conclusions
    • References
  • Chapter 11. Applications of carbon dots in biosensing and cellular imaging
    • Abstract
    • 11.1 Introduction
    • 11.2 CDs as Fluorescent Probes for Sensing of Biomolecules
    • 11.3 CDs as Fluorescent Probes for Imaging of Biomolecules and Cells
    • 11.4 Conclusions and Perspectives
    • References
  • Chapter 12. Inorganic nanobiomaterials for medical imaging
    • Abstract
    • 12.1 Introduction
    • 12.2 Solid Silica Nanoparticles (SNPs)
    • 12.3 Gold Nanoparticles (AuNPs)
    • 12.4 Iron Oxide Nanoparticles
    • 12.5 Quantum Dots (QDs)
    • 12.6 Conclusions
    • References
  • Chapter 13. Nanobiomaterials in X-ray luminescence computed tomography (XLCT) imaging
    • Abstract
    • 13.1 Introduction
    • 13.2 XLCT Imaging System
    • 13.3 XLCT Reconstruction Methods
    • 13.4 Future Directions in XLCT
    • 13.5 Conclusions
    • Acknowledgments
    • References
  • Chapter 14. Multifunctional carbon nanotubes in cancer therapy and imaging
    • Abstract
    • 14.1 Introduction
    • 14.2 Carbon Nanotubes
    • 14.3 Transcellular Trafficking Mechanism of f-CNTs
    • 14.4 CNTs in Cancer Therapy
    • 14.5 CNTs in Imaging
    • 14.6 Conclusions
    • Acknowledgments
    • References
  • Chapter 15. Functionalized carbon nanotubes and their promising applications in therapeutics and diagnostics
    • Abstract
    • 15.1 Introduction
    • 15.2 Origin and Historical Perspective of CNT
    • 15.3 Classification of CNTs
    • 15.4 Methods for Preparation of CNTs
    • 15.5 Functionalization of CNTs
    • 15.6 Characterization of CNTs
    • 15.7 Cellular Trafficking of CNTs
    • 15.8 Applications of CNTs
    • 15.9 Role of CNTs in Diagnostics
    • 15.10 Toxicity Consideration of CNTs
    • 15.11 Biodistribution of CNTs
    • 15.12 Regulatory Considerations
    • 15.13 Conclusions
    • References
  • Index

Details

No. of pages:
518
Language:
English
Copyright:
© William Andrew 2016
Published:
Imprint:
William Andrew
eBook ISBN:
9780323417389
Hardcover ISBN:
9780323417365

About the Editor

Alexandru Grumezescu

Alexandru Grumezescu

Dr. Alexandru Mihai Grumezescu is Assistant Professor at the Department of Science and Engineering of Oxide Materials and Nanomaterials, in the Faculty of Applied Chemistry and Materials Science, with a second affiliation to the Faculty of Medical Engineering, at the Politehnica University of Bucharest in Romania. He is an experienced and oft-published researcher and editor in the field of nano and biostructures, and he is the Editor-in-Chief of three journals: Biointerface Research in Applied Chemistry, Letters and Applied NanoBioScience, Biomaterials and Tissue Engineering Bulletin, and Journal of Food Bioengineering and Nanoprocessing. He also serves as editor or guest editor for several notable journals. Dr. Grumezescu has published 150 peer-reviewed papers, 20 book chapters, 8 co-authored books and 21 edited books. He has developed two new research directions related to bio-applications of metal oxide nanoparticles: (i) functional metal oxide nanostructures to improve the delivery of antimicrobials in active form with a high efficiency against Gram-positive and Gram-negative bacteria; and (ii) smart metal oxide nanostructures, functionalized with different fatty acids, essential oils or in combination with organic polymers, to inhibit bacterial colonization of different medical or industrial surfaces. Dr Alexandru Mihai Grumezescu is also Assistant Professor at the Department of Science and Engineering of Oxide Materials and Nanomaterials, in the Faculty of Applied Chemistry and Materials Science at the Politehnica University of Bucharest in Romania. He is an experienced and oft-published researcher and editor in the field of nano- and biostructures, and he is the Editor-in-Chief of four journals: Biointerface Research in Applied Chemistry, Letters and Applied NanoBioScience, Biomaterials and Tissue Engineering Bulletin, and Journal of Food Bioengineering and Nanoprocessing. He also serves as editor or guest editor for several notable journals. Dr Grumezescu has published 160 peer-reviewed papers, 20 book chapters, 9 coauthored books, and 21 edited books. Other details are available at http://grumezescu.com/.

Affiliations and Expertise

Assistant Professor, Department of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Applied Chemistry and Materials Science and Faculty of Medical Engineering, Politehnica University of Bucharest, Romania