Muscle Biopsy: A Practical Approach

4th Edition

Expert Consult; Online and Print


  • Victor Dubowitz
  • Caroline Sewry
  • Anders Oldfors
    • Print ISBN 9780702043406
    • Electronic ISBN

    Key Features

    • Bridge the gap between clinical syndromes/disorders and their underlying pathologies with the guidance of muscle disease expert, Dr. Victor Dubowitz, who skillfully guides you through the complexities of pathologic diagnoses and their implications for clinical treatment.
    • Understand and apply expert techniques for obtaining a muscle biopsy, and familiarize yourself with the histochemical, histological, electron microscopical, and molecular appearance of normal muscle and the pathology of individual muscle disease.
    • Read the entire contents and download all of the images online at Expert Consult.

    Table of Contents

    Section 1 The Biopsy: Normal and Diseased Muscle

    1. The procedure of muscle biopsy

    2. Histological and histochemical stains and reactions

    3. Normal muscle

    4. Definition of pathological changes seen in muscle biopsies

    5. Ultrastructural changes in diseased muscle

    6. Immunohistochemistry

    7. How to read a biopsy

    Section 2 Pathological Muscle: Individual Diseases

    8. Classification of neuromuscular disorders

    9. Neurogenic disorders

    10. Muscular dystrophies and allied disorders I: Duchenne and Becker muscular dystrophy

    11. Muscular dystrophies and allied disorders II: limb-girdle muscular dystrophies

    12. Muscular dystrophies and allied disorders III: congenital muscular dystrophies

    13. Muscular dystrophies and allied disorders IV: Emeryƒ{Driefuss muscular dystrophies and Bethlem myopathy

    14. Muscular dystrophies and allied disorders V: facioscapulohumeral dystrophy, myotonic dystrophy, oculopharyngeal muscular dystrophy

    15. Congenital myopathies

    16. Myofibrillar myopathies

    17. Metabolic myopathies I: glycogenoses

    18. Metabolic myopathies II: lipid related disorders and mitochondrial myopathies

    19. Endocrine disorders

    20. Ion channel disorders

    21. Myasthenic syndromes

    22. Inflammatory myopathies

    23. Toxic and drug-induced myopathies
    Russell Lane, Charing Cross Hospital

    Appendix 1. Glossary of commonly used terms




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    © 2013
    Saunders Ltd.
    Print ISBN:
    Electronic ISBN: