MRI Atlas of Human White Matter presents an atlas to the human brain on the basis of T 1-weighted imaging and diffusion tensor imaging. A general background on magnetic resonance imaging is provided, as well as the basics of diffusion tensor imaging. An overview of the principles and limitations in using this methodology in fiber tracking is included. This book describes the core white-matter structures, as well as the superficial white matter, the deep gray matter, and the cortex. It also presents a three-dimensional reconstruction and atlas of the brain white-matter tracts. The Montreal Neurological Institute coordinates, which are the most widely used, are adopted in this book as the primary coordinate system. The Talairach coordinate system is used as the secondary coordinate system. Based on magnetic resonance imaging and diffusion tensor imaging, the book offers a full segmentation of 220 white-matter and gray-matter structures with boundaries.

Key Features

  • Visualization of brain white matter anatomy via 3D diffusion tensor imaging (DTI) contrasts and enhances relationship of anatomy to function
  • Full segmentation of 170+ brain regions more clearly defines structure boundaries than previous point-and-annotate anatomical labeling, and connectivity is mapped in a way not provided by traditional atlases
  • Electronic files with viewing software can be made available via CD and/or BrainNavigator, allowing readers access to raw image files


Clinicians, researchers and graduate students in neuroscience, neurology, neurosurgery and radiology

Table of Contents

Preface Chapter 1. Introduction     1. Magnetic resonance imaging (MRI)     2. Diffusion tensor imaging (DTI)          2.1. The diffusion tensor and the diffusion ellipsoid          2.2. Two-dimensional visualization of DTI results          2.3. Three-dimensional reconstruction of white matter tracts Chapter 2. Three-Dimensional Reconstruction of White Matter Tracts     1. Data acquisition     2. Data processing     3. Reconstruction of tracts          3.1. Algorithm          3.2. Editing of reconstruction results using multiple ROIs          3.3. ROI drawing strategy          3.4. Limitations of DTI-based reconstruction     4. 3D visualization     5. Nomenclature and annotation     References Chapter 3. Three-Dimensional Atlas of Brain White Matter Tracts     1. Tracts in the brainstem     2. Projection fibers     3. Association fibers     4. Commissural fibers     5. Overall view of reconstructed fibers     References Chapter 4. MRI/DTI Atlas of the Human Brain in the ICBM-152 Space     1. Reference systems          1.1. The Talairach system and cytoarchitectonic map          1.2. MNI coordinates     2. Creation of the atlas          2.1. MRI acquisition          2.2. Data processing          2.3. Normalization          2.4. Parcellation of the gray and white matter          2.5. Probabilistic tractography (population averaged white matter tracts)          2.6. Brodmann ’ s map assignment          2.7. Electronic versions of the atlas and software packages for image analyses     3. Nomenclature     References Subject Index A companion website to support this book can be found at:


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© 2011
Academic Press
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About the authors

Kenichi Oishi

Affiliations and Expertise

Department of Radiology Johns Hopkins University of Medicine Baltimore, MD USA

Andreia V. Faria

Affiliations and Expertise

Department of Radiology Johns Hopkins University School of Medicine Baltimore, MD USA

Peter C M van Zijl

Affiliations and Expertise

Department of Radiology Johns Hopkins University of Medicine Baltimore, MD USA Johns Hopkins University School of Medicine, Baltimore, Maryland, USA

Susumu Mori

Affiliations and Expertise

Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD, USA


"Overall, NeuroApps: MRI Atlas of Human White Matter will be of great interest to anyone in need of an introduction to human white matter anatomy and particularly valuable to those using diffusion tensor imaging…The conversion to an iPad app has been well implemented and makes the atlas all the more accessible and attractive."--American Medical Association, JAMA, December 5, 2012, Vol 308, No 21, page 2280