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Molecular Players in IPSC Technology - 1st Edition - ISBN: 9780323900591

Molecular Players in IPSC Technology

1st Edition

Editor: Alexander Birbrair
Paperback ISBN: 9780323900591
Imprint: Academic Press
Published Date: 19th August 2021
Page Count: 300
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Table of Contents

  1. H1foo in iPSCs
    Keiichi Fukuda, MD, PhD, Professor, Department of Regenerative Medicine and Advanced Cardiac Therapeutics, Keio University, Tokyo, Japan
    2. Nanog in iPSCs
    Alejandra Guberman, PhD, Independent Researcher, IQUIBICEN, Buenos Aires, Argentina
    3. ERK1/2 signaling in iPSCs
    Ye Lei, PhD, Associate Researcher, Mount Sinai Health System, Elmhurst, NY, USA
    4. SOCS3/JAK2/STAT3 pathway in iPSCs
    Xinxia Wang, PhD, Associate Professor, College of Animal Sciences, Zhejiang University, Hangzhou, China
    5. KLFs and iPSCs
    Vincent Yang, MD, PhD, Chair of the Department of Medicine, Professor of Medicine, Physiology and Biophysics, Stony Brook University, Stony Brook, NY, USA
    6. The Role of Cell Cycle Regulation on Reprogramming efficiency
    Irina Neganova, PhD, Senior Research Associate, Newcastle University, Newcastle upon Tyne, Northumberland, United Kingdom
    7. Ion Channels in hiPSC-Derived Cardiomyocytes
    Jonathan Cordeiro, PhD, Research Scientist, Masonic Medical Research Institute, Utica, NY, USA
    8. Exosomal microRNAs in iPSCs
    Yan Li, PhD, Associate Professor, Chemical & Biomedical Engineering, FAMU-FSU College of Engineering, Tallahassee, FL, USA
    9. Notch signaling in iPSCs
    Thanaphum Osathanon, PhD, Research Assistant, Research Department, Faculty of Dentistry, Chulalongkorn University, Chulalongkorn, Thailand
    10. Cardiac lineage commitment of iPSCs (and signaling pathways)
    Hee Cheol Cho, PhD, Associate Professor, Departments of Biomedical Engineering and Pediatrics at Emory and Georgia Tech, Atlanta, GA, USA
    11. Induced pluripotency and intrinsic reprogramming factors adults stem cells versus somatic cells
    Sudhir Shenoy, PhD, Associate Professor, Yenepoya Research Center, Karnataka, India
    12. Ca2+ signaling in iPSCs
    Martin Morad, PhD, Professor of Cell Biology & Anatomy, School of Medicine, University of South Carolina, Columbia, SC, USA
    13. Molecular Strategies for Stablizing hiPSCs
    Evan Y. Snyder, MD, PhD, Professor, Human Genetics Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA
    14. Generation of iPSCs with Substitutes for Yamanaka's Four Transcription Factors
    Xiong Xiao, PhD, Researcher, Southwest University, Chongqing, China


Molecular Players in IPSC Technology, Volume Twelve, the latest release in the Advances in Stem Cell Biology series, is a timely and expansive collection of comprehensive information and new discoveries in the field. The book addresses the molecular players underlying iPSC formation, maintenance, expansion and differentiation. This volume covers H1foo, Nanog, ERK1/2 signaling, hiPSC-derived cardiomyocytes, exosomal microRNAs, notch signaling, and much more. The volume is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation, and is contributed by world-renowned authors in the field.

The discovery of induced pluripotent stem cells has revolutionized biomedical research, hence the timeliness of this comprehensive volume.

Key Features

  • Provides an overview of the fast-moving field of stem cell biology and function, regenerative medicine and therapeutics
  • Covers the molecular players underlying iPSC formation, maintenance, expansion and differentiation
  • Contributed by world-renowned experts in the field


Researchers and scientists in stem cell therapy, cell biology, regenerative medicine, and organ transplantation. Graduate and undergraduate students in the above fields


No. of pages:
© Academic Press 2021
19th August 2021
Academic Press
Paperback ISBN:

Ratings and Reviews

About the Editor

Alexander Birbrair

Dr. Alexander Birbrair received his bachelor’s biomedical degree from Santa Cruz State University in Brazil. He completed his PhD in Neuroscience, in the field of stem cell biology, at the Wake Forest School of Medicine under the mentorship of Osvaldo Delbono. Then, he joined as a postdoc in stem cell biology at Paul Frenette’s laboratory at Albert Einstein School of Medicine in New York. In 2016, he was appointed faculty at Federal University of Minas Gerais in Brazil, where he started his own lab. His laboratory is interested in understanding how the cellular components of different tissues function and control disease progression. His group explores the roles of specific cell populations in the tissue microenvironment by using state-of-the-art techniques. His research is funded by the Serrapilheira Institute, CNPq, CAPES, and FAPEMIG. In 2018, Alexander was elected affiliate member of the Brazilian Academy of Sciences (ABC), and, in 2019, he was elected member of the Global Young Academy (GYA). He is the Founding Editor and Editor-in-Chief of Current Tissue Microenvironment Reports, and Associate Editor of Molecular Biotechnology. Alexander also serves in the editorial board of several other international journals: Stem Cell Reviews and Reports, Stem Cell Research, Stem Cells and Development, and Histology and Histopathology.

Affiliations and Expertise

Department of Pathology, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil Department of Radiology, Columbia University Medical Center, Medical Center, USA